Clinical trials: Experimental, completed
Stress, Stress Disorders
Manage Your Workingnegative Thoughts Through Hypnosis
Medical doctor generally are exposed to several risks and pressures, it is not a case that several meta-analyses have shown high stress and anxiety level in these workers. Stress management represents a very important topic.
- Trial name
- Hypnosis (NCT06778109)
- Testing
- Experimental: Hypnosis and negative memory
- Where
- 2 sites in Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Padova
Education
Video-supported Training in Line With the Health Belief Model
Summary The only treatment method for those with incurable, irreversible, progressive, acute or chronic liver disease is liver transplantation.
- Trial name
- NCT06138379
- Testing
- Experimental: 1st Experimental Group, Experimental: 2nd Experimental Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain and Anxiety
The Effect of Virtual Reality on Pain and Anxiety During Colposcopic Biopsy: A Randomized Controlled Trial
The study was planned as a prospective, two-arm (1:1) randomized controlled experimental study to determine the effect of virtual reality applied during colposcopic biopsy on pain and anxiety.
- Trial name
- NCT06811259
- Testing
- Virtual reality (in experimental group), Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mersin University
Fibromyalgia Syndrome
Effect of Soundscapes on Emotional Distress in Fibromyalgia: a 4×4 Crossover Trial
This study tests whether different types of sounds can help reduce emotional distress in people with fibromyalgia. Fibromyalgia is a condition that causes widespread muscle and joint pain and makes people extra sensitive to…
- Trial name
- FMSounDistress (NCT07231289)
- Testing
- Natural soundscape exposure, Urban soundscape exposure, Broadband sound active control
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Universidad de Granada
Postoperative Pain Score
Single Port Insufflation RCT
The goal of this clinical trial is to learn if decreasing insufflation pressure during minimally invasive single port robotic sacrocolpopexy improved postoperative pain without impacting surgeon intraoperative visualization.
- Trial name
- NCT06990750
- Testing
- 15 mmHg, 12 mmHg
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Chicago
Priapism, Reperfusion Injury
Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats
The condition known in medical terminology as 'Priapism' refers to the state of erection in the male sexual organ persisting partially or completely for more than 4 hours without sexual stimulation or orgasm.
- Trial name
- NCT07391709
- Testing
- Ischemic priapism + reperfusion, Ischemic priapism + reperfusion + ALA
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Panic Disorder
Self-Guided CBT Mobile App for Treatment-Resistant Panic Disorder (CBT) Cognitive Behavioral Therapy
Treatment-resistant panic disorder (TRPD) is characterized by persistent panic symptoms despite adequate pharmacological and/or psychotherapeutic treatment.
- Trial name
- (CBT) (NCT07391943)
- Testing
- Experimental - Self-Guided CBT Mobile App
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Birth
The Effect of Creating a Birth Story in the Labor Room on Fear of Childbirth
The aim of this study is to reduce the fears of women who will give birth and increase their comfort. In the literature review conducted for this purpose, no study has yet been found that examines the effect of creating a birth…
- Trial name
- NCT07382609
- Testing
- BIRTH STORY EXPERIMENTAL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Inonu University
Breast Cancer
Preoperative Localization of Infraclinical Breast Tumors: Isotopic Localization by iodine125 Seed Versus Standard Localization Using a Metal Wire
This is a monocentric, non-inferiority, randomized cohort study with an open 1:1 ratio comparing the impact of iodine seed tumor localization (arm B) vs.
- Trial name
- IodineBreast (NCT02759133)
- Testing
- Metal wire, Radioactive Iodine Seed
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Antoine Lacassagne
Chronic Rhinosinusitis With Nasal Polyps
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis
- Trial name
- WAYPOINT (NCT04851964)
- Testing
- Experimental: Tezepelumab, Mometasone furoate or equivalent intranasal corticosteroid
- Where
- 112 sites in United States, Canada and 8 more
- Volunteers
- 416 people
- Sponsor
- AstraZeneca
Colonic Polyp
Endoscopic Submucosal Dissection (ESD) Versus Endoscopic Mucosal Resection (EMR) for Large Non Pedunculated Colonic Adenomas: a Randomized Comparative Trial
Initially developed in Japan for the treatment of endemic superficial gastric cancers, endoscopic submucosal dissection (ESD) allows resection of pre-neoplastic and neoplastic lesions of the digestive tract into a single…
- Trial name
- RESECT COLON (NCT03962868)
- Testing
- Experimental procedure : ESD, Comparison procedure: WF-piece meal EMR
- Where
- 6 sites in France
- Volunteers
- 360 people
- Sponsor
- University Hospital, Limoges
Liver Transplant
Targeting Trimethylamine N-Oxide for Cardiovascular Health In Liver Transplant Recipients
Despite medical and surgical advances, long-term survival in liver transplant (LT) recipients is compromised by an increased risk of cardiovascular disease (CVD) after transplant, the mechanisms of which are still not fully…
- Trial name
- NCT06043531
- Testing
- Experimental: EVOO
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Virginia Commonwealth University
Neck Pain, Chronic Pain
Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Chronic Neck Pain
The aim of this study is to compare the effects of applying percutaneous neuromodulation with performing only therapeutic exercise in patients with non-specific chronic neck pain.
- Trial name
- NCT06695949
- Testing
- Percutaneous neuromodulation., Therapeutic Exercise.
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Almeria
Hypopituitarism, Central Diabetes Insipidus
Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Hypopituitarism, Central Diabetes Insipidus, Panhypopituitarism, Psychological Disorder
- Trial name
- NCT04897802
- Testing
- Experimental: GLP1-RA (exenatide) administration
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Overweight and Obesity, Healthy
the Safety, Tolerability and Pharmacokinetics of Mulberry Twig Alkaloids in Human
This trial is conducted in China. The aim of the trial is to investigate safety, tolerability, and pharmacokinetics of the Mulberry Twig Alkaloids tablets (WH006) in healthy ，overweight and obesity subjects.
- Trial name
- NCT06490263
- Testing
- Experimental: Mulberry Twig Alkaloids Tablets 126 mg single dose in healthy subjects, Mulberry Twig Alkaloids Tablets with single dose in healthy subjects, Mulberry Twig Alkaloids Tablets with multiple dose in healthy subjects
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Beijing Wehand-Bio Pharmaceutical Co., Ltd
COVID-19 Pneumonia
Phase I Clinical Trial of GEN2-Recombinant COVID-19 Vaccine (CHO Cells) in Healthy People Aged 18 and Above
phase I study will evaluate the safety and tolerability of GEN2-Recombinant COVID-19 Vaccine (CHO cells) in healthy people aged 18 years and older.
- Trial name
- NCT05408312
- Testing
- Experimental Vaccine 1, Experimental Vaccine 2, Experimental Vaccine 3
- Where
- China
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Overweight, Metabolic Syndrome
Clinical Trials of VitalPLANT and Helichrysum Infusions in Adults ( VitalPlant_SMILJ )
The study evaluates the effects of VitalPLANT and Helichrysum italicum on different components of the metabolic syndrome. The components of metabolic syndrome will be measured at baseline and one week after daily consumption of…
- Trial name
- NCT06866314
- Testing
- Tea infusion VitalPLANT - Active comparator, Tea infusion VitalPLANT + Helichrysum Italicum - Experimental product
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Balance, Kinesiophobia
The Effect of Hemsball in the Older People
This study aimed to determine the effect of hemsball activity on balance, kinesiophobic attitudes, and frailty levels in older male individuals.
- Conditions
- Balance, Kinesiophobia, Frailty, Older People
- Trial name
- NCT07344662
- Testing
- Experimental: Hemsball
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Physical Activity
Neighborhood Park Youth Sports Program Fee Waiver and Intensive Family Outreach
To evaluate a park-level intervention to increase child moderate/vigorous physical activity (MVPA), and decrease sedentary time among low-income racially/ethnically diverse children ages 6-12 yrs.
- Trial name
- PARKS (NCT05231837)
- Testing
- Experimental: Fee Waiver, Fee Waiver Plus Intensive Outreach
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Budesonide, Olfaction Disorders
Trial Evaluating the Efficacy of Local Budesonide Therapy in the Management of Hyposmia in COVID-19 Patients Without Signs of Severity
The initial symptoms described in the first cases of COVID-19 were mainly fever and respiratory signs. Recently, there has been an increase in cases of hyposmia without associated nasal obstruction or rhinorrhea.
- Conditions
- Budesonide, Olfaction Disorders, SARS-CoV-2, Anosmia
- Trial name
- COVIDORL (NCT04361474)
- Testing
- Budesonide Nasal, Physiological serum
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild