Clinical trials: Hydrocortisone
Borderline Personality Disorder
Role Of Sensitivity to neuroEndocrine Systems in Social Decisions
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- ROSES (NCT06018727)
- Testing
- Hydrocortisone, Yohimbine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prostate Cancer
[18F] Fluorocholine FCH Positron Emission Tomography (PET)/Computed Tomography (CT) for Detection of Prostate Cancer Lymph Nodes Metastases
The objective of this trial is to assess the value of 18F-choline PET/CT for the detection of regional lymph node metastases from prostate cancer.
- Trial name
- PROPET (NCT00670527)
- Testing
- [18F] Fluorocholine PET/CT
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Odense University Hospital
Hypercortisolism, Type 2 Diabetes (T2DM)
Salivary Cortisol and Hypercortisolism in Type 2 Diabetes
The goal of this observational study is to explore the prevalence of hypercortisolism in a population with difficult to control type 2 diabetes despite receiving standard-of-care therapies.
- Trial name
- NCT07156370
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai 6th People's Hospital
Breastfeeding
Effect of Early Skin to Skin Contact on Breast Feeding Behaviour in Term Newborns: A Randomized Controlled Trial
Aims and Objectives Aim To determine the effect of delivery room Skin To Skin contact on breast feeding behavior of term neonates born by normal vaginal delivery at 36-48 hours.
- Trial name
- NCT00776789
- Testing
- skin to skin contact, Control group
- Where
- India
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Severe Viral Pneumonia(Not Include COVID-19)
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Uterine Blood Mesenchymal Stem Cells Injection for the Treatment of Severe Pneumonia Caused by Viruses
This study is a multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of Menstrual blood-derived Mesenchymal Stem Cells (SC01009) injection for the treatment of severe…
- Trial name
- NCT06693362
- Testing
- Drug therapy, Standard Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Cushing's Syndrome
A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia
This is an observational study to confirm the presence of recurrent or persistent endogenous Cushing's syndrome in patients who have had primary surgical and/or radiation therapy for Cushing's disease and continue to manifest…
- Trial name
- NCT00796783
- Testing
- Cushing's syndrome confirmation
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Corcept Therapeutics
21-hydroxylase Deficiency
Examining Genetic Differences Among People With 21-Hydroxylase Deficiency
Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the amount of steroids that the body forms. The most common form of CAH is 21-hydroxylase deficiency (21OHD), which leads to cortisol deficiency.
- Trial name
- NCT00542841
- Testing
- Hydrocortisone withdrawal
- Where
- 3 sites in United States, Brazil
- Volunteers
- 99 people
- Sponsor
- Maria I. New
Sepsis, Septic Shock
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
A great interest exists regarding substances with an immunomodulatory effect for sepsis patients. Recent data have shown that intravenous vitamin C, together with corticosteroids and thiamine, could prevent progressive organ…
- Trial name
- NCT05192213
- Testing
- Vitamin C
- Where
- 12 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Hospital Sirio-Libanes
Stress, Cortisol; Hypersecretion
Effect of Maternal Cortisol Levels on Fetal Heart Rate Patterns
Objective: This study was designed to determine whether maternal cortisol levels affect fetal heart rate (FHR) patterns at third trimester. Design: Cross-sectional descriptive study.
- Conditions
- Stress, Cortisol; Hypersecretion, Fetal Heart Rate Disorder
- Trial name
- NCT05503433
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Halic University
Diabetes Mellitus Type 2
Comparison of Progressive Muscle Relaxation and Stretching Exercises in Diabetic Population
The goal of this clinical trial is to compare the effects of Progressive muscle relaxation and stretching exercises mediated by stress on heart rate variability, cortisol level, galvanic skin response and perceived stress scale.
- Trial name
- NCT06780878
- Testing
- Progressive muscle relaxation technique, Stretching exercises, Control Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
- Trial name
- NCT06275490
- Testing
- Partially Demineralized Dentin Block, L-PRF block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Critical Illness
Cortisol Levels as a Measure of Accumulated Physiological Stress in ICU Patients Undergoing Mechanical Ventilation
Critical illness is a situation of severe and prolonged stress for patients with mechanical ventilation (MV). Between 40-80% of these patients present the Post-ICU syndrome, a set of physical, cognitive, psychological alterations…
- Trial name
- Corti-COG (NCT03736135)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Corporacion Parc Tauli
Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood
Feasibility and Acceptability of Remote Saliva Collection
The purpose of this study is to evaluate the practicality and acceptability of collecting biological samples and health information from childhood survivors of acute lymphoblastic leukemia (ALL) and their siblings.
- Trial name
- NCT07884474
- Testing
- Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Autonomic Disturbances in Parkinson's Disease
Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson's Disease -Treatment
Disabling symptoms of blood pressure dysregulation, impaired swallowing and digestion are common amongst Parkinson's patients. So far the exact pathophysiology for this is not fully understood.
- Trial name
- NCT01993680
- Testing
- Pyridostigmine bromide, fludrocortisone
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Christian Baumann
Stress, Pituitary-Adrenal System
Modulating Stress-Reactivity by Real-Time Multimodal Functional Neuroimaging Based Neurofeedback
The overall goal of the outlined study is to establish a Real-Time (RT) functional Magnetic Resonance Imaging (fMRI) Neurofeedback (NF) (RT-fMRI-NF) protocol aiming at modulating neural, endocrine, and subjective reactivity to…
- Trial name
- NCT02560233
- Testing
- Contingent RT-fMRI-NF
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Papilla Reconstruction
Modified Pedicle Subepithelial Connective Tissue Graft for Interdental Papillary Reconstruction Around Delayed Implants in the Esthetic Zone: A Case Series Trail
This case series trial aims to evaluate the effect of a modified pedicle subepithelial connective tissue graft in creating anatomical papilla around one-stage delayed implant in the esthetic zone to establish better esthetics.
- Trial name
- delay implant (NCT04843826)
- Testing
- papilla reconstruction
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ahmed Sadek Mohamed
Hypoactive Sexual Desire Disorder (HSDD)
Stress Hormones, Mood and Women's Sexual Desire (MODEST)
Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA).
- Trial name
- MODEST (NCT01702818)
- Where
- Canada
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Addison Disease
Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure
The conventional glucocorticoid replacement therapy in primary adrenal insufficiency- Addison's disease,renders the cortisol levels unphysiological, which may cause symptoms and long-term complications.
- Trial name
- NCT01847690
- Testing
- Hydrocortisone
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Primary Aldosteronism Due to Aldosterone Producing Adenoma
Rapid Cortisol Assay in Adrenal Vein Sampling
Background: Adrenal vein sampling (AVS) is the gold standard test for the subtyping of primary aldosteronism (PA). This procedure is hampered by unsuccessful bilateral cannulation of adrenal veins, which can occur in up to two…
- Trial name
- I-PADUA (NCT03449797)
- Testing
- AVS performed with no intraprocedural rapid cortisol assay, AVS performed plus intraprocedural rapid cortisol assay
- Volunteers
- 200 people
- Sponsor
- University Hospital Padova
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