Clinical trials: Hydrocortisone, completed
Dental Anxiety
Anxiety Levels of Patients Subjected to Endodontic and Restorative Treatment
This study aimed to compare the stress levels induced in patients at the beginning and at the end of endodontic and restorative treatments and access relationship between dental anxiety levels and cortisol levels.
- Trial name
- NCT06764758
- Testing
- Endodontic treatment, Restorative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Baskent University
Healthy Young Adults
Physiological and Psychological Effects
Stress-related mental health problems such as depression, anxiety, and stress are common among young adults and are often linked to both psychological and physiological changes in the body.
- Trial name
- DASS21-CORT (NCT07398729)
- Testing
- Calisthenic exercise and Motivational factors, Motivational factors
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Bingol University
Pregnancy Loss, Anxiety
EFT and Music on Psychological Development, Well-Being Status and Cortisol Level in Pregnant Women
Emotional freedom technique and music were applied to pregnant women who experienced prenatal loss. Emotional freedom technique group, music group and control groups each consisted of 53 pregnant women.
- Trial name
- EFT (NCT05344144)
- Testing
- Emotional Freedom Technique, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Congenital Adrenal Hyperplasia, Hyperplasia
Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia
This is an open-label, non-randomized, single arm proof-of concept feasibility trial comparing standard oral hydrocortisone (HC) treatment with a six-week intervention of interval bolus delivery (pulsatile) of subcutaneous (SQ)…
- Conditions
- Congenital Adrenal Hyperplasia, Hyperplasia, Adrenal Hyperplasia, Congenital Disorders
- Trial name
- NCT03718234
- Testing
- Subcutaneous hydrocortisone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Healthy
The Effect of Relaxation Response Training on Declarative Memory and Salivary Cortisol in Older Adults
To evaluate whether a 5-week relaxation response intervention influences the learning, memory or attention of healthy older adults.
- Trial name
- NCT00179530
- Testing
- Relaxation Response
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Insomnia
Eszopiclone Treatment & Cortisol Responsivity
This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia.
- Trial name
- NCT00889200
- Testing
- eszopiclone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Butler Hospital
Leukemia
Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
Phase II trial to study the effectiveness of radiation therapy following chemotherapy in treating children with CNS relapse from acute lymphoblastic leukemia.
- Trial name
- NCT00002704
- Testing
- filgrastim, asparaginase, cyclophosphamide
- Where
- 70 sites in United States, Canada and 2 more
- Volunteers
- 156 people
- Sponsor
- National Cancer Institute (NCI)
L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia
Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic Leukemia
Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Imatinib mesylate may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.
- Conditions
- L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, Non-T, Non-B Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia
- Trial name
- NCT00049569
- Testing
- cytarabine, methotrexate, vincristine sulfate
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute (NCI)
Schizophrenia, Schizo-Affective Disorder
Correlation Between Clinical Deterioration in Schizophrenic Patients and Hair Cortisol Levels
The importance of stress as a possible deteriorating factor for schizophrenic patients is well documented. However, this notion is based on subjective experience and retrospective psychological analysis.
- Trial name
- NCT01754532
- Testing
- Hair Sample
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Shalvata Mental Health Center
Cushing's Syndrome
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Patients will receive Corlux (mifepristone) daily for up to 24 weeks. Assessments of the signs and symptoms of Cushing's syndrome will be obtained.
- Trial name
- SEISMIC (NCT00569582)
- Testing
- mifepristone
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- Corcept Therapeutics
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Stress, Anxiety
Canine Assisted Therapy to Reduce Emergency Care Provider Stress
The main study hypothesis is that emergency healthcare workers on shift who interact for 5 min with a therapy dog and handler will have lower perceived and manifested stress response compared with use of a time out that includes…
- Trial name
- CANINE II (NCT03628820)
- Testing
- Dog Therapy, Coloring
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Indiana University
Addison Syndrome
Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure
Effects of adrenal steroids is generelly drawn from studies of hypercortisolism. The effects of physiological cortisol substitution and withdrawal is studied and related to the clinical syndrome of adrenal insufficiency.
- Trial name
- NCT00442390
- Testing
- hydrocortisone substitution therapy versus withdrawal
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Depressive Disorder, Major
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response?
The primary purpose of this study is to examine whether IV hydrocortisone can speed up the time required for Venlafaxine XR to work.
- Trial name
- NCT00186264
- Testing
- venlafaxine XR, hydrocortisone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stanford University
Acute Myeloid Leukemia
Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
The purpose of this study is to test the safety and determine the best dose of venetoclax and cytarabine when given with or without idarubicin in treating pediatric patients with acute myeloid leukemia (AML) that did not respond…
- Trial name
- NCT03194932
- Testing
- Venetoclax, Cytarabine, Idarubicin
- Where
- 3 sites in United States
- Volunteers
- 62 people
- Sponsor
- St. Jude Children's Research Hospital
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement
Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCT
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment
- Trial name
- JUMP-ESTHETIC (NCT07700706)
- Testing
- No Grafting, Silicate-Added β-TCP Putty, Extended Sticky Bone
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Healthy
Standardized 1µg Adrenocorticotropic Hormone Stimulation Test, and Salivary Cortisol Concentration During the Test
Study objectives: First, to determine whether intravenous injection of 1 mcg adrenocorticotropic hormone (ACTH) through short cannula, in healthy participants, provides reliable results of cortisol response, and whether this…
- Trial name
- NCT02413944
- Testing
- ACTH stimulation test
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Burnout Syndrome, Nurse's Role
The Effects of "Three Good Things" Positive Psychotherapy on Nurses' Burnout
A randomized, controlled trial was conducted for 73 Chineses nurses from The Second Xiangya Hospitcal of Central South University (33 in the experimental group, 40 in the control group).
- Trial name
- NCT03645798
- Testing
- "Three good things" therapy, Normal psychological instruction
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Central South University
Hypopituitarism
Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients
In growth hormone deficient patients: Determination of endogenous circulating ghrelin levels, ghrelin effects on insulin sensitivity, appetite, energy metabolism, and signal transduction in fat and muscle.
- Trial name
- NCT00139945
- Testing
- Human acylated ghrelin
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Gastrointestinal Diseases
The Effect of Dream Doctors in Children Undergoing Digestive Endoscopic Procedures
Background: Performance of endoscopy in children requires more patience, experience, and expertise than in adults. The anxiety of the children is related to parent's separation, loss of self-control, unknown surroundings and…
- Trial name
- NCT02668679
- Testing
- Sedation of children during gastroscopy with and without the presence of dream doctor, evaluation of stress with PPI and GSR, blood specimens for stress hormones
- Where
- Israel
- Volunteers
- 99 people
- Sponsor
- HaEmek Medical Center, Israel