Clinical trials: Hydrocortisone, completed
Stress, Psychological, Burnout, Professional
Online Mindfulness Program for Stress Management
This is a prospective parallel non-blinded randomized study with two arms, an intervention group and an active control group. Sixty healthy, but stressed nurses will be randomly assigned to either participate in a 6-week…
- Trial name
- IGEM (NCT03753360)
- Testing
- Internet-Based Mindfulness Program - Stress Free Now for Healers, Active Control Group - Relaxing Music
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The Cleveland Clinic
Diabetes Mellitus, Type I Diabetes
The Effect of Mindfulness Based Stress Reduction in Patients With Painful Diabetic Peripheral Neuropathy
By 2020, it is estimated that 3.7 million Canadians will have diabetes mellitus, with type 2 diabetes (T2DM) accounting for more than 90% of cases.
- Conditions
- Diabetes Mellitus, Type I Diabetes, Type II Diabetes, Diabetic Peripheral Neuropathy
- Trial name
- AWARE (NCT02127762)
- Testing
- Mindfulness Based Stress Reduction
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Sepsis, Alcoholism
Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis
Patients with alcohol use disorders are often cared for in the intensive care unit (ICU). We estimate that close to half of the patients we care for in our ICU have alcohol use disorders.
- Trial name
- NCT00615862
- Testing
- Observational study; no interventions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Polytraumatism
Treatment of Polytraumatisms With Corticoids
Interest of treatment of polytraumatisms with corticoids (hydrocortisone) for patient with relative adrenocortical insufficiency on frequency of nosocomial infection, and hemodynamic complications and organs injuries.
- Trial name
- Hypolyte (NCT00563303)
- Testing
- hydrocortisone, NaCl
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Hemorrhoids, Pregnancy
The Safety of Proctofoam-HC in the Third Trimester of Pregnancy
The purpose of this study is to evaluate the fetal safety of topical application of Proctofoam-HC®, an antihemorrhoidal, in the third trimester of pregnancy.
- Trial name
- NCT00405288
- Testing
- Proctofoam-HC®
- Where
- 2 sites in Canada
- Volunteers
- 408 people
- Sponsor
- The Hospital for Sick Children
Primary Aldosteronism, Primary Aldosteronism Due to Aldosterone Producing Adenoma
A Novel and Efficient Biochemical Screening Strategy for Glucocorticoid-Remediable Aldosteronism: Combined 1-mg Overnight Dexamethasone Suppression Test and Steroid Profile
This prospective observational study evaluates a simplified biochemical screening strategy to differentiate Glucocorticoid-Remediable Aldosteronism (GRA) from Aldosterone-Producing Adenoma (APA).
- Trial name
- NCT07700888
- Testing
- 1 mg overnight dexamethasone inhibition test
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Cytochrome P450 Oxidoreductase Deficiency, Hypertension
Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency
This study investigates the etiology of hypertension and endothelial damage in patients with Cytochrome P450 Oxidoreductase (POR) deficiency.
- Conditions
- Cytochrome P450 Oxidoreductase Deficiency, Hypertension, Endothelial Dysfunction, Congenital Adrenal Hyperplasia
- Trial name
- PORENDO (NCT06756620)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ozge Bayrak Demirel
Healthy Adult Participants, Acute Stress Reaction
Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test
This study investigates whether the psychophysiological benefits of breathing exercises are driven by a specific physiological rhythm (6 breaths per minute) or by the general psychological experience of performing a structured…
- Conditions
- Healthy Adult Participants, Acute Stress Reaction, Stress Biomarkers, Healthy
- Trial name
- NCT07529379
- Testing
- Coherent Breathing (6 bpm)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Cushing's Disease
Cushing's Disease Complications
This study aims at investigating the complications of Cushing's disease in "de novo" patients. A series of investigations will assay before treatment and every year thereafter during a 3 years follow-up period the various…
- Trial name
- COMPLICUSHING (NCT02568982)
- Testing
- Exams and questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sepsis
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
In this study , we suggest that the use of combination of Hydrocortisone, Ascorbic Acid, and Thiamine in patient with sepsis may decrease mortality rate and improve the outcome.
- Trial name
- NCT04160676
- Testing
- Hydrocortisone, Ascorbic acid, Thiamine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Anxiety
The Effect of Aromatherapy Applied to the Patients in the Urodynamic Procedure
This randomized controlled study is planned to determine the effect of aromatherapy applied to patients in the urodynamic procedure on patients' anxiety and serum cortisol levels.
- Trial name
- NCT05255874
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mersin University
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
- Trial name
- NCT06275490
- Testing
- Partially Demineralized Dentin Block, L-PRF block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alcohol Drinking, Drinking Behavior
Neuroimaging Mechanisms by Which Memory and Glucocorticoids Promote Risky Drinking
The purpose of this study is to determine whether hydrocortisone biases formation of alcohol-related memories to potentiate drinking.
- Conditions
- Alcohol Drinking, Drinking Behavior, Episodic Memory, Long-term Memory
- Trial name
- NCT04896489
- Testing
- Hydrocortisone 20 MG
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yale University
Addison Syndrome
Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure
Effects of adrenal steroids is generelly drawn from studies of hypercortisolism. The effects of physiological cortisol substitution and withdrawal is studied and related to the clinical syndrome of adrenal insufficiency.
- Trial name
- NCT00442390
- Testing
- hydrocortisone substitution therapy versus withdrawal
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Other Preterm Infants
Use of Topical Lidocaine to Reduce Pain in Preterm Infants Receiving Nasal CPAP Continuous Positive Airway Pressure
The main purpose of this study is to evaluate the relative efficacy of topical lidocaine on reducing pain associated with the application of nasal CPAP in preterm infants
- Trial name
- NCT02268968
- Testing
- Lidocaine 2% Gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Internal Hemorrhoids
Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids
The primary objective of this study is to determine the safety and efficacy of G\&W Laboratories' Anucort HC TM (Hydrocortisone Acetate) 25mg Rectal Suppositories in subjects with internal hemorrhoidal symptoms.
- Trial name
- NCT01913158
- Testing
- Anucort-HC, 25 Mg Rectal Suppository
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- G & W Laboratories Inc.
Depression
Fludrocortisone and Information Processing in Healthy Volunteers
Stimulating the mineralocorticoid receptor (MR) may restore a disturbed balance as seen in depression. In this double-blind, randomized, placebo-controlled trial the investigators will test the effects of a single dose (500mg)…
- Trial name
- NCT01648998
- Testing
- Fludrocortisone
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Depression Anxiety Disorder, Demography, Family
The Effect of Mindfulness-based Stress Reduction Programme Given to Infertile Women
Purpose of the Study This study aims to determine the effect of mindfulness-based stress reduction program given to infertile women on perceived stress, anxiety, depression and salivary cortisol.
- Conditions
- Depression Anxiety Disorder, Demography, Family, Awakening Early
- Trial name
- NCT06283693
- Testing
- mindfulness-based stress reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Tendinopathy
High Volume Injection or Autologous Conditioned Plasma (ACP) in Chronic Achilles Tendinopathy
The aim of the study is to examine patients with chronic Achilles Tendinopathy (AT) and to compare the effect of high volume injection (HVI) or autologous conditioned plasma (ACP) in combination with eccentric training to placebo…
- Trial name
- NCT02417987
- Testing
- High Volume injection, Autologous conditioned plasma (ACP)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Caregiver, Education
The Psychobiological Effects of Laughter Yoga: An Intervention Study
This study was conducted to determine the effect of Laughter Yoga-Based Mental Health Enhancement Training, applied to mothers of children with special needs, on the burden of care, positive mental health, perceived stress, and…
- Trial name
- NCT07314463
- Testing
- Laughter Yoga-Based Mental Health Strengthening Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University