Clinical trials: Hydrocortisone
Obesity, Addison's Disease
The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation
Replacing glucocorticoid in a dose dependent manner (including doses within the physiological range) to subjects with adrenal insufficiency will increase visceral fat accumulation independently of total fat mass.
- Trial name
- NCT00688987
- Testing
- Hydrocortisone, Isocaloric Diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Prostate Cancer
A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as aminoglutethimide or ketoconazole may stop the adrenal glands from producing hormones.
- Trial name
- NCT00006371
- Testing
- aminoglutethimide, ketoconazole, therapeutic hydrocortisone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Septic Shock, Sepsis
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
The purpose of this study is to find out whether stress doses of hydrocortisone attenuate coagulation dysfunction in patients with septic shock.
- Trial name
- NCT02266589
- Testing
- Hydrocortisone
- Volunteers
- 84 people
- Sponsor
- Nanjing PLA General Hospital
Stress, Cortisol
The Effect of Massage on Stress in Premature Babies
The practices of the neonatal intensive care unit that reduce the stress of premature babies and respond to behavioral cues have a positive effect on the development of newborns.
- Trial name
- NCT05580874
- Testing
- Massage, Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Katip Celebi University
Hiv
Effects of Glucocorticoids on Cognition in HIV-infected Women
Despite treatment with antiretroviral therapy, women living with HIV continue to experience cognitive impairment. Psychological risk factors, including stress, impair cognition more in HIV-infected women than HIV-uninfected…
- Trial name
- MsSCORE (NCT03237689)
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Johns Hopkins University
Pituitary Neoplasms
Effect of Dexmedetomidine on Plasmatic Cortisol Response in Transsphenoidal Surgery
Use of dexmedetomidine in pituitary tumor resection surgery as adjuvant drug and its relation to cortisol levels during postoperative period.
- Trial name
- NCT02549768
- Testing
- Dexmedetomidine, Sodium Chloride 0.9%
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Euglycemia, Hypoglycemia
Intravenous Exenatide (Byetta) During Surgery
The purpose of this project is to study if intravenous Exenatide is effective at maintaining normal blood glucose levels and preventing low blood glucose levels during surgery.
- Conditions
- Euglycemia, Hypoglycemia, Hyperglycemia
- Trial name
- NCT00882050
- Testing
- Exenatide 0.27 ng/kg/min, Exenatide 0.41 ng/kg/min
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Thomas Jefferson University
Dental Anxiety
Exercise Treatment of Dental Anxiety
A single bout of physical activity (treadmill)immediately prior to the dental examination reduces anxiety in patients with dental phobia.
- Trial name
- NCT01933191
- Testing
- Aerobic treadmill exercise
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Stress Reaction, Nurse's Role
Mindfulness Meditation for Nursing Students
Mindfulness meditation was used to reduce stress and its responses such as cortisol and C-reactive protein (CRP) among healthy and ill individuals in various cultures, but their effects have not yet been studied among Jordanian…
- Trial name
- NCT05099224
- Testing
- Mindfulness meditation
- Where
- Jordan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Stress, Mood
Effect of Black Cumin Seed Oil Supplementation on Cortisol, Stress and Mood
The primary objective of this study will be to collect data to support the role of black cumin seed oil, also known as black seed oil (BSO), in moderating the stress response, including objective markers of stress (cortisol/DHEA)…
- Trial name
- NCT06950424
- Testing
- black cumin seed oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shawn Talbott
Arginine Vasopressin Deficiency, Diabetes Insipidus
Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls
This study aims to investigate the potential beneficial effects of intranasal oxytocin compared to placebo on emotion recognition and acute psychosocial stress in patients with arginine vasopressin deficiency compared to matched…
- Trial name
- OxyMOTION (NCT06676774)
- Testing
- Oxytocin nasal spray
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Psychological Distress, Insomnia
Clinical Trial for Acupuncture in Adolescents With Psychological Distress and Insomnia
This is an assessor-blinded, randomized, MAS-controlled trial. A total of 148 adolescents aged 15-22 years experiencing mild to moderate anxiety or depressive symptoms will be recruited.
- Trial name
- NCT06638450
- Testing
- Dense Cranial Electroacupuncture Stimulation plus Body Acupuncture (DCEAS+BA), Minimal Acupuncture Stimulation (MAS)
- Where
- Hong Kong
- Volunteers
- 148 people
- Sponsor
- The University of Hong Kong
Acute Severe Colitis (ASC)
Ulcerative Colitis Endoscopic Index of Severity and Fecal Calprotectin to Predict the Reaction to Corticosteroids of Acute Severe Ulcerative Colitis
For acute severe colitis (ASC) patients, corticosteroids (CS) was recommended as the first-line treatment in the guideline, but patients have a great risk of requiring colectomy or turning to second-line treatment.
- Trial name
- NCT02922374
- Testing
- corticosteroids
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Jinling Hospital, China
Acute Lymphoblastic Leukemia
Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)
The goal of this study is to find a safe dose of sirolimus that can be used with a standard dose of L-asparaginase. To find the safe dose, the investigators will give the first patient a very small dose of sirolimus (smaller than…
- Trial name
- NCT00957320
- Testing
- Sirolimus, PEG-asparaginase
- Where
- United States
- Sponsor
- Emory University
Depression, Anxiety
A Mindfulness-Based Stress Reduction Training Program Model
Mindfulness-based practices are used to regulate mood, alleviate or completely eliminate symptoms that cause stress and depression, and positively influence well-being.
- Conditions
- Depression, Anxiety, Stress, Well-Being, Psychological
- Trial name
- NCT07544355
- Testing
- The mindfulness group-"Mindfulness-Based Stress Reduction Program", The life skills workshop group-"Lifestyle Management and Well-being Workshop"
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Chronic Stress Disorder
Mindfulness, Empathy and Social Integration. Its Relation With Chonic Stress
The objective of this project is to evaluate the effects of promoting the learning of empathy and pro-social behavior in health and interpersonal relationships in middle-aged children It has been shown that pro-social behavior…
- Trial name
- NCT04177017
- Testing
- Mindfulness-based intervention
- Where
- Argentina
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Adrenal Insufficiency
Updated Diagnostic Cortisol Values for Adrenal Insufficiency
The purpose of this study is to determine the cortisol levels that most accurately diagnose a patient with adrenal insufficiency, a condition in which cortisol levels are too low for daily living.
- Trial name
- NCT05149638
- Testing
- Cosyntropin stimulation test
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Internal Hemorrhoids
Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids
The primary objective of this study is to determine the safety and efficacy of G\&W Laboratories' Anucort HC TM (Hydrocortisone Acetate) 25mg Rectal Suppositories in subjects with internal hemorrhoidal symptoms.
- Trial name
- NCT01913158
- Testing
- Anucort-HC, 25 Mg Rectal Suppository
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- G & W Laboratories Inc.
Exercise, Physical Performance
Examination of Certain Blood Parameters Following Performance and Acute Exercise at Specific Times of the Day
This study aims to investigate whether the time of day at which acute exercise is performed influences physical performance and acute hormonal and biochemical responses in healthy young male soccer players.
- Conditions
- Exercise, Physical Performance, Circadian Rhythm
- Trial name
- Acute & Blood (NCT07825740)
- Testing
- Standardized Acute Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Firat University
Stress Psychological, Stress Physiological
Relaxation-Response-based Mental Health Promotion - Open and Calm 2013
The purpose of the study is to investigate health-promoting and stress-reducing psychological, physiological and hormonal effects of a 9-week meditation-based course in personal health and to examine potential baseline factors…
- Conditions
- Stress Psychological, Stress Physiological, Quality of Life
- Trial name
- RR-MHP OC13 (NCT02140307)
- Testing
- Relaxation Response-based Mental Health Promotion (RR-MHP)
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Steen G Hasselbalch
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