Clinical trials: Hydrocortisone, completed
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Hemodynamic Measure, Cognitive Performance in Healthy Volunteers
Assessing the Impact of High Theacrine Doses on Hemodynamic Measures
This project measured physiological and cognitive variables to determine the effectiveness of Theacrine (TCR) as a stimulant at doses greater than those previously tested.
- Trial name
- NCT07376564
- Testing
- Low dose theacrine, Medium dose theacrine, High dose theacrine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Titch Madzima
Cognitive Impairment, Cognitive Decline
Music Therapy for Older Adults With Cognitive Decline Living in Care Homes
This research aims to investigate whether the use of music-improvisation therapy for older adult participants can lead to improvements in cognitive ability levels, especially in attentional functions.
- Trial name
- NCT05856604
- Testing
- Music Therapy, Storytelling
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Middlesex University
Borderline Personality Disorder, Oxytocin
Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder
This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
- Trial name
- OXT-CORT-BPD (NCT05357521)
- Testing
- stress test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Adrenal Insufficiency
An Investigational Study of Hydrocortisone
This study will investigate a new drug called Infacort®; a newly-developed immediate release formulation of a well-established drug called hydrocortisone.
- Trial name
- NCT01960530
- Testing
- Hydrocortisone granules, Hydrocortisone Tablet, i.v. Hydrocortisone Injection
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Neurocrine UK Limited
Acute Lymphoblastic Leukemia (ALL)
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
The purpose of Phase 1b of this study is to: Asses the safety, tolerability and activity of carfilzomib, alone and in combination with induction chemotherapy, in children with relapsed or refractory acute lymphoblastic leukemia…
- Trial name
- NCT02303821
- Testing
- Carfilzomib, Dexamethasone, Mitoxantrone
- Where
- 122 sites in United States, Argentina and 31 more
- Volunteers
- 141 people
- Sponsor
- Amgen
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Postoperative Pain, Caesarean Section
Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section
The purpose of this study is to evaluate the clinical efficacy of intraperitoneal hydrocortisone 100 mg administration in reducing postoperative pain and inflammatory response in patients undergoing elective Caesarean section…
- Conditions
- Postoperative Pain, Caesarean Section, Peritoneal Inflammation
- Trial name
- NCT07892547
- Testing
- hydrocortisone, Nornal Saline
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Raditsya Mada Gautama, MD
Type 2 Diabetes, Hypertension
Pilot Study of Aprepitant Effect on Aldosterone Secretion in Diabetic Patient (Diabetes Mellitus) With Hypertension Associated With Low Renin
Aldosterone regulation is mediated by hormonal control, and nervous control. Autonomic nervous system action could be mediated by neuropeptides in the adrenal gland.
- Trial name
- APHOS-02 (NCT02811055)
- Testing
- Blood sampling, Blood Pressure Measurement, electrocardiogram
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Rouen
Leukemia
High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002865
- Testing
- filgrastim, cyclophosphamide, cytarabine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Infections
The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers
Corticosteroids are substances produced by the adrenal gland to help the body fight against infection or injury. Hydrocortisone is a man-made form of this substance.
- Trial name
- NCT01064986
- Testing
- Endotoxin, Lipopolysaccharide, LPS, Endotoxin, Lipopolysaccharide, LPS /Epinephrine, Hydrocortisone
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Recovery, Strength
The Effects of KSM-66 Ashwagandha Supplementation on Recovery and Muscle Strength in Academy Athletes
This double-blind, randomised, placebo-controlled trial will examine the effects of 42-day root extract ashwagandha (KSM-66) supplementation on recovery and muscle strength in male and female rugby and water polo players.
- Conditions
- Recovery, Strength, Exercise Training
- Trial name
- NCT07041853
- Testing
- KSM-66 Ashwagandha
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus Xenograft
The aim of this study is to clinically and radiographically evaluate the dimensional changes of hard tissue after using Partially Demineralized Dentin Block versus Xenograft in the esthetic zone.
- Trial name
- NCT06429540
- Testing
- Partially Demineralized Dentin Block, Xenograft
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Phobia
Cortisol in the Treatment of Phobias
The aim of this prospective, double-blind, placebo-controlled, randomized study is to investigate if glucocorticoid treatment, in combination with exposure therapy, helps to reduce phobic fear in patients with phobia.
- Trial name
- NCT00451750
- Testing
- Cortisol
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Osteopenia of Prematurity
The Effect of Daily Exercise Program on Bone Mineral Density and Cortisol Level in Preterm Infants
ABSTRACT Objective: This randomized controlled double-blinded experimental study was carried out to determine the effects of daily exercise program on bone mineral density and cortisol level in preterm infants with very low birth…
- Trial name
- NCT03773679
- Testing
- Daily Exercise
- Volunteers
- 24 people
- Sponsor
- TC Erciyes University
Stress, Psychological, Burnout, Professional
Online Mindfulness Program for Stress Management
This is a prospective parallel non-blinded randomized study with two arms, an intervention group and an active control group. Sixty healthy, but stressed nurses will be randomly assigned to either participate in a 6-week…
- Trial name
- IGEM (NCT03753360)
- Testing
- Internet-Based Mindfulness Program - Stress Free Now for Healers, Active Control Group - Relaxing Music
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The Cleveland Clinic
Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
Phase II trial to study the effectiveness of combining rituximab and rasburicase with combination chemotherapy in treating young patients who have newly diagnosed advanced B-cell leukemia or lymphoma.
- Conditions
- Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma
- Trial name
- NCT00057811
- Testing
- doxorubicin hydrochloride, cyclophosphamide, methotrexate
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Children's Oncology Group
Aluminum Phosphide Poisoning
Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases
study of some laboratory and clinical findings which may show the severity of aluminium phosphide toxicity and the need of the cases to be admitted to ICU
- Trial name
- NCT05215444
- Testing
- some prognostic factors
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Adrenocortical Carcinoma
Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)
This study will investigate the safety and efficacy of Relacorilant in combination with Pembrolizumab for Patients with Adrenocortical Carcinoma which Produces Too Much Stress Hormone (Cortisol).
- Trial name
- NCT04373265
- Testing
- Relacorilant, Pembrolizumab
- Where
- 6 sites in United States
- Volunteers
- 15 people
- Sponsor
- Corcept Therapeutics