Clinical trials: Hydrocortisone, completed
Snake Bites
Improving Safety of Antivenom in People Bitten by Snakes
A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, \& hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in…
- Trial name
- NCT00270777
- Testing
- adrenaline, promethazine, hydrocortisone
- Where
- Sri Lanka
- Volunteers
- 1,000 people
- Sponsor
- University of Kelaniya
Healthy
Enhancing Emotional and Motivational Development to Support Well-being and Retention in Diverse University Students
Higher education is crucial for young adults in their intake of knowledge and skills to further their careers and reach their potentials. However, going through college is not necessarily an easy path.
- Trial name
- NCT05294913
- Testing
- Contextualized Wish-Outcome-Obstacle-Plan (WOOP) intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Mindfulness, Dental Implant
The Effect of Mindfulness Meditation During Dental Implant Surgery
The aim of this pioneer study was to evaluate the efficacy (heart rate value, blood pressure, oxygen saturation, cortisol levels, BIS monitoring, patients' anxiety) of Mindfulness Meditation as a sedative technique during dental…
- Trial name
- NCT05748223
- Testing
- Mindfulness Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Adrenal Insufficiency
Mass Spectrometry Based Cutoffs for Cortisol After Stimulation Tests
There are two main stimulation tests used to decide if a patient has cortisol deficiency. It is the "synacthen test", were we stimulate the patient with intramuscular or intravenous synacthen ( ACTH) to see how much cortisol the…
- Trial name
- NCT02818660
- Testing
- Synachten
- Where
- Norway
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Psychotic Disorders
Hormonal and Inflammatory Biomarkers and Response to Cognitive Remediation in Recent-onset Psychosis
This study aims to explore whether hormones or inflammatory markers are associated with cognitive changes following cognitive remediation therapy (CRT) in people with a recent-onset psychotic disorder.
- Trial name
- NCT04418570
- Testing
- cognitive remediation, attendance to an Early Intervention Service for Psychosis
- Volunteers
- 28 people
- Sponsor
- Corporacion Parc Tauli
Aging
Effect of Estrogen & Stress for Postmenopausal Women
The study tests the hypothesis that estradiol administration exacerbates the effects of the stress hormone cortisol on cognition and mood for postmenopausal women.
- Trial name
- NCT00220454
- Testing
- Climara, Hydrocortone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Therapeutic Touch, Cancer
Reiki for Cancer: Pain, Anxiety, and Stress
The goal of this clinical trial is to investigate the effects of Reiki, Sham Reiki, and Progressive Relaxation Exercise on the levels of pain, anxiety, and stress in cancer patients.
- Trial name
- NCT06296680
- Testing
- Reiki, Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ege University
Cannabis Use Disorder
Cannabinoids and Biological Reactivity to Stress
The goal of this study is to test the impact of two drugs that produce temporary stress-like symptoms, both in isolation and together, on cannabis use motivation in individuals with Cannabis Use Disorder.
- Trial name
- COBRAS (NCT06430580)
- Testing
- Hydrocortisone Oral, Yohimbine Hydrochloride
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Florida State University
Hemiarthroplasty, Arthroplasty, Replacement, Hip
Effects of Surgery Start Time on Postoperative Interleukin-6, Interleukin-8, and Cortisol
Cortisol is a hormone that increases after trauma or surgery and has circadian rhythm. It has a form that is increased in the morning and decreased in the evening.
- Trial name
- NCT03076827
- Testing
- Total hip replacement, Hemi-arthroplasty
- Volunteers
- 44 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Healthy Volunteers
Fludrocortisone in Healthy Volunteers (AFLUCO4)
Fludrocortisone, in association with hydrocortisone, has demonstrated an improvement in survival in septic shock patients with relative adrenal insufficiency.
- Trial name
- AFLUCO4 (NCT02140918)
- Testing
- Fludrocortisone 100 μg, Fludrocortisone 200 μg, Fludrocortisone 400 μg
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Coping Skills, Oxytocin
Oxytocin Buffers Stress Response in Individuals With Impaired Coping Abilities
This study investigated, if people with impaired coping abilities benefit from intranasal oxytocin application.
- Conditions
- Coping Skills, Oxytocin, Stress
- Trial name
- NCT01065610
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Osnabrueck
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cushing's Disease
Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease
This is a randomized, double-blind, multicenter, phase III study to evaluate the safety and efficacy of 2 dosing regiments of Pasireotide long acting release (LAR) in patients with Cushing's disease.
- Trial name
- NCT01374906
- Testing
- pasireotide LAR, SOM230 LAR 30 mg, SOM230 LAR 10 mg
- Where
- 82 sites in United States, Argentina and 18 more
- Volunteers
- 150 people
- Sponsor
- Novartis Pharmaceuticals
Immediate Dental Implants
Accuracy of Selective Laser Sinteredcomputer Guided Stents Versus Digital Light Processing Stents
patient with non-restorable tooth in the esthetic zone will be recruited in the study. a traumatic is done and implant will be placed using either digital light processed guides for control group or selective laser sintering…
- Trial name
- RCT (NCT03287934)
- Testing
- selective laser sintered stent, digital light processing(dlp)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Thrombotic Thrombocytopenic Purpura
Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP)
This research involves the use of immune base therapy as an adjunct to plasma exchange, the present standard of care for thrombotic thrombocytopenic purpura (TTP). Funding source -FDA OOPD
- Trial name
- NCT00713193
- Testing
- Cyclosporine, Prednisone
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Ohio State University
Healthy
Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes
The purpose of this research is to determine if patients who receive phenytoin (also commonly known as Dilantin) before taking corticosteroids will show less memory impairment and hypomanic symptoms (feelings of agitation…
- Trial name
- NCT00591006
- Testing
- Phenytoin (brand name Dilantin), Hydrocortisone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Inflammatory Response
Steroids in Bilateral Total Knee Replacement
Inflammation related to cytokine release is known to occur with surgery. The cytokine IL6, a major marker of inflammation is known to increase during total joint replacement surgery.
- Trial name
- NCT01399268
- Testing
- Hydrocortisone, Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Phobia
Cortisol in the Treatment of Phobias
The aim of this prospective, double-blind, placebo-controlled, randomized study is to investigate if glucocorticoid treatment, in combination with exposure therapy, helps to reduce phobic fear in patients with phobia.
- Trial name
- NCT00451750
- Testing
- Cortisol
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Cushing's Syndrome
In Vivo Study of Interactions Between the Endocannabinoid System and the Corticotropic Axis in Man
Working hypothesis: the interactions between the endogenous endocannabinoïds (ECS) - and cortisol, the end product of the Hypothalamo-Pituitary-Adrenal (HPA) axis may play a role in the pathophysiology of Cushing's syndrome.
- Trial name
- VISECA (NCT02889224)
- Testing
- Obese, Hypercortisolism, Hydrocortisone
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Dental Implants
Vestibular Socket Therapy (VST) Versus Partial Extraction Therapy
The current randomized clinical trial aimed to compare the VST versus Partial Extraction Therapy (PET) for immediate implant placement in the esthetic zone in class I fresh extraction sites.
- Trial name
- NCT05112796
- Testing
- Class I extractions sites received immediate implants using the Vestibular Socket Therapy, class I extractions sites received immediate implants using the Partial Extraction Therapy
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman