Clinical trials: Hydrocortisone, completed
Healthy
Enhancing Emotional and Motivational Development to Support Well-being and Retention in Diverse University Students
Higher education is crucial for young adults in their intake of knowledge and skills to further their careers and reach their potentials. However, going through college is not necessarily an easy path.
- Trial name
- NCT05294913
- Testing
- Contextualized Wish-Outcome-Obstacle-Plan (WOOP) intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Adrenal Insufficiency
Mass Spectrometry Based Cutoffs for Cortisol After Stimulation Tests
There are two main stimulation tests used to decide if a patient has cortisol deficiency. It is the "synacthen test", were we stimulate the patient with intramuscular or intravenous synacthen ( ACTH) to see how much cortisol the…
- Trial name
- NCT02818660
- Testing
- Synachten
- Where
- Norway
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Autism Spectrum Disorder
Effects of Mounted vs Unmounted Human-Equine Interaction on Autistic Youth
The goal of this clinical trial is to learn how interacting with horses affects autistic children and youth. The main questions it aims to answer are: How does interacting with horses affect cortisol, heart-rate variability, and…
- Trial name
- NCT07897123
- Testing
- Mounted Human-equine Interaction, Unmounted Human-equine Interaction, No-Horse Control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Colorado State University
Obesity
Clinical and Metabolic, Immunological and Microbiological Characteristics of Obese Patients
The purpose of the study: To develop a differentiated management strategy for obese children based on the analysis of the relationship between their clinical, metabolic, immunological and microbiological status Research…
- Trial name
- NCT05920785
- Testing
- Determination of the level of interleukins in the blood, stool analysis for the intestinal microbiome, general clinical tests, glucose tolerance test, hormonal profile
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samara State Medical University
Stress, Psychological
Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision
A prospective observational study was conducted to analyze the correlation between systolic blood pressure, diastolic blood pressure, mean arterial pressure，heart rate and plasma corticotropin, cortisol during surgical skin…
- Trial name
- NCT03892538
- Where
- China
- Volunteers
- 134 people
- Sponsor
- JingCang
Atopic Dermatitis
A Study of Lebrikizumab in Participants With Persistent Moderate to Severe Atopic Dermatitis
This randomized, double-blind, placebo-controlled study will evaluate the safety and efficacy of lebrikizumab administered subcutaneously (SC) in adult participants with persistent moderate to severe atopic dermatitis (AD) who…
- Trial name
- NCT02340234
- Testing
- Lebrikizumab, TCS Cream
- Where
- 74 sites in United States, Australia and 12 more
- Volunteers
- 212 people
- Sponsor
- Hoffmann-La Roche
Sleep Disturbance, Mood Disturbance
Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
This study aims to investigate the effect of a 4-week dietary intervention of 300mg encapsulated aqueous lemon balm extract on measures of sleep quality, mood and well-being, alongside relevant biomarkers of circadian rhythms in…
- Trial name
- NCT05422599
- Testing
- Lemon balm
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Reading
Acute Myocarditis
The Role of Levosimendan as Inotropic Agent in Acute Aluminum Phosphide-induced Cardiotoxicity
To evaluate the potential role of levosimendan as an inotropic agent in aluminum phosphide-induced cardiotoxicity
- Trial name
- NCT06478667
- Testing
- levosemindan
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Leukemia, Lymphoma
Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more tumor cells.
- Trial name
- NCT00002700
- Testing
- asparaginase, cyclophosphamide, cytarabine
- Where
- 44 sites in Belgium, Croatia and 8 more
- Volunteers
- 392 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pregnancy Loss, Anxiety
EFT and Music on Psychological Development, Well-Being Status and Cortisol Level in Pregnant Women
Emotional freedom technique and music were applied to pregnant women who experienced prenatal loss. Emotional freedom technique group, music group and control groups each consisted of 53 pregnant women.
- Trial name
- EFT (NCT05344144)
- Testing
- Emotional Freedom Technique, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Septic Shock
ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock
The purpose of this study is to find out whether adult patients admitted to the Intensive Care Unit with septic shock who are given hydrocortisone compared to placebo (a dummy solution), will have an improved rate of survival 90…
- Trial name
- ADRENAL (NCT01448109)
- Testing
- Hydrocortisone, Sterile air filled vial
- Where
- 70 sites in Australia, Denmark and 3 more
- Volunteers
- 3,800 people
- Sponsor
- The George Institute
Acute Myocardial Infarction
Hair Cortisol and the Risk of Acute Myocardial Infarction
Aim of the study: To evaluate whether hair cortisol levels are elevated in patients admitted with acute MI compared to controls. Study steps: 1. Introduction of the study to the participants and inform consent signing 2.
- Trial name
- NCT00682487
- Testing
- Hair sampling for cortisol
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Meir Medical Center
Bronchopulmonary Dysplasia
Outcome of Extremely Preterm Infants Who Received Systemic Postnatal Corticosteroid for Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia is a complication of prematurity. Postnatal corticosteroid is used to treat the inflammatory part of this pathology, in particular to wean premature infants from the ventilator at the end of the first…
- Trial name
- DEPRECOD (NCT05055193)
- Testing
- Evaluation at 24 months corrected age: respiratory outcome, Neurodevelopmental outcome, Growth outcome
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Hospices Civils de Lyon
Neonatal Abstinence Syndrome, Aromatherapy
The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels
Determine the effectiveness of lavender and chamomile aromatherapy of mitigation of symptoms of Neonatal Abstinence Syndrome
- Trial name
- NCT03097484
- Testing
- lavender and chamomile essential oils
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- John M. Daniel
Molar Incisor Hypomineralization
Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) is a developmental condition that affects the enamel of permanent molars and incisors in children and may cause tooth sensitivity, discomfort, and difficulties during dental treatment.
- Trial name
- NCT07389148
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Prader-Willi Syndrome
Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls
The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.
- Trial name
- NCT00932932
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Glioblastoma (GBM)
Effect of stRess and exeRcize on the Outcome After Chemo-Radiation
Glioblastoma (GBM) is a highly malignant, incurable primary brain tumor. Due to the nature of this disease and the extent of the treatment (surgery followed by chemoradiation according to the Stupp trial) patients undergo…
- Trial name
- ERROR (NCT05431348)
- Testing
- Smartwatch, Serum Cortisol, Questionnaires
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Maastricht Radiation Oncology
Pharmacodynamics, Healthy Subjects
A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects
This is a Phase I, Randomized, Single-Blind, Crossover Study to Assess the Pharmacodynamics of AZD9977 following Single-Dose administration to healthy male subjects
- Trial name
- NCT02532998
- Testing
- AZD9977 oral suspension, Fludrocortisone, tablets, Eplerenone, tablets
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Endometrial Thickness, Pregnancy Rate
the Effect of Clomiphene Citrate Plus Estradiol Valerate Versus Letrozole on Endometrial Thickness and Pregnancy Rate in Infertile Women
The present randomized double blind study has been carried out in Gynecology and Obstetrics Department, Faculty of Medicine, Zagazig university on 70 women were previously received clomiphene citrate alone as management of…
- Trial name
- NCT04619914
- Testing
- Clomid; Aventis pharma S.AE, Global Napi pharmaceuticals, Cairo, Egypt, letrozole (Femara; Novartis pharma AG, Basle, Switzerland)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Laylay Mohammed Khalleefah Alhibshi
Systemic Inflammatory Response Syndrome, Hyperglycemia
The Importance of Adrenomedullin (AM) on ACTH-Cortisol-Glucose Axis
Hyperglycemia is frequent manifestations of the human metabolic response to systemic inflammatory response syndrome (SIRS),sepsis and septic shock, and are implicated in the clinical outcome.
- Trial name
- AM (NCT00459511)
- Testing
- Blood AM, IL-6, ACTH, Cortisol, Glucose and Insulin
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo