Clinical trials: Hydrocortisone, completed
Ulcerative Colitis
A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis
PHASE : IV TYPE OF STUDY : With direct benefit. DESCRIPTIVE : Multicentre, randomized, open label study. INCLUSION CRITERIA : Acute severe ulcerative colitis.
- Trial name
- ACTIVE (NCT02425852)
- Testing
- Azathioprine, Infliximab, Prednisolone
- Where
- 16 sites in France
- Volunteers
- 65 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Granuloma, Tracheostomy
Treatment of Tracheostomy Granulomas
This study plans to learn more about the different ways used to treat tracheostomy granulomas. Investigators want to see which standard of care method (steroid application, silver nitrate, or betadine) is more successful in…
- Trial name
- NCT02116608
- Testing
- Betadine, Silver Nitrate, Hydrocortisone Butyrate Cream, 1.0%
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Stress, Psychological
Effect of Low Doses of Vitamin C on Salivary Cortisol , Heart Rate , Blood Pressure During Group Presentation
Vitamin C (ascorbic acid) is a well-known antioxidant that is involved in anxiety, stress, depression, fatigue and mood state in humans .
- Trial name
- NCT04135378
- Testing
- ascorbic acid
- Where
- Iraq
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kufa University
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Acute Myeloid Leukemia
Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies
PRIMARY OBJECTIVE: This is a pilot study to characterize the toxicity profile, to determine the maximum tolerated dose of the combination of crenolanib and sorafenib, and to determine the feasibility of administering these drugs…
- Trial name
- NCT02270788
- Testing
- Crenolanib, Sorafenib, methotrexate, hydrocortisone and cytarabine with leucovorin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Depressive Disorder
The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
The aim of the present study is to compare the antidepressant effect of electroconvulsive therapy ( ECT) with that of low frequency repetitive transcranial magnetic stimulation of the right prefrontal cortex.
- Trial name
- NCT00299403
- Testing
- Right prefrontal lowfrequency ( 1 hz) rTMS., Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Orthostatic Hypotension, Hemodynamic Instability
Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery
The purpose of this study is to evaluate the effect of low dose versus high dose steroids vital signs of patients currently on steroids or recently treated with steroids undergoing major colorectal surgery.
- Conditions
- Orthostatic Hypotension, Hemodynamic Instability, Fever, Hypothermia
- Trial name
- NCT01559675
- Testing
- Hydrocortisone High Dose, Hydrocortisone Low Dose
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Cedars-Sinai Medical Center
Molar Incisor Hypomineralization
Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) is a developmental condition that affects the enamel of permanent molars and incisors in children and may cause tooth sensitivity, discomfort, and difficulties during dental treatment.
- Trial name
- NCT07389148
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Systolic Heart Failure
Hair Cortisol and Testosterone in Heart Failure
The purpose of this study is to determine whether hair cortisol and testosterone levels correlate with heart failure status in patient with chronic congestive heart failure.
- Trial name
- NCT01139697
- Testing
- Hair sampling
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Meir Medical Center
Adrenocortical Carcinoma
The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma
This work will evaluate the effects of mitotane treatment on serum protein concentrations in patients treated for ACC with mitotane therapy and compare them to patients with an adrenal neoplasm and pregnant cohort.
- Trial name
- MitoS-FP (NCT05344027)
- Testing
- Mitotane
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Shock
Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study
Approximately 20,000 children per year in North America present to the hospital with severe shock. Children who develop this condition have very low blood pressures and as a result may suffer damage to their internal organs and…
- Trial name
- STRIPES (NCT02044159)
- Testing
- Hydrocortisone
- Where
- 7 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Children's Hospital of Eastern Ontario
Covid-19
COVID-19 Tests: Nasopharyngeal Swab vs Saliva Collected With Salivette® Cortisol for Viral RNA Sampling for RT-qPCR
The main objective of the tests is to establish saliva collection with Salivette® Cortisol.
- Trial name
- NCT04599959
- Testing
- Sampling of SARS-CoV-2 RNA from nasopharyngeal swab specimen or saliva collected via Salivette Cortisol
- Where
- Mexico
- Volunteers
- 151 people
- Sponsor
- Boehringer Ingelheim
Adrenal Insufficiency
A Study of Chronocort® Versus Cortef ® in Healthy Adult Male Subjects
This was a single centre, open label, randomised, two period, crossover study to evaluate the bioavailability of Chronocort® versus Cortef® immediate release hydrocortisone tablets in dexamethasone-suppressed healthy adult male…
- Trial name
- NCT03343327
- Testing
- Chronocort®, Cortef®
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Neurocrine UK Limited
Herpes Labialis
Study of ME-609 and Acyclovir for Treatment of Herpes Simplex Labialis in Immunocompromised Patients
The purpose of this study is to evaluate the episode duration of a herpes labialis recurrence in immunocompromised patients treated with ME-609 or Acyclovir.
- Trial name
- NCT00735761
- Testing
- ME-609, Acyclovir in ME-609 vehicle (5% acyclovir)
- Volunteers
- 201 people
- Sponsor
- Medivir
Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL)
Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome
The purpose of this study is to test the safety of selinexor (KPT-330) and to find the highest dose of selinexor (KPT-330) that can be given safely when it is combined with two chemotherapy drugs (fludarabine and cytarabine).
- Conditions
- Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Myelodysplastic Syndrome (MDS), Mixed Phenotype Acute Leukemia (MPAL)
- Trial name
- NCT02212561
- Testing
- Selinexor, Fludarabine, Cytarabine
- Where
- 6 sites in United States
- Volunteers
- 19 people
- Sponsor
- St. Jude Children's Research Hospital
Posttraumatic Stress Disorder
Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder
To test overall efficacy of hydrocortisone on reexperience of traumatic memories (intrusions) and overall symptomatology in patients meeting criteria of complex chronic PTSD.
- Trial name
- NCT01108146
- Testing
- Arm 1 Hydrocortisone 10 mg, Arm 2 Hydrocortisone 30 mg
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Skin-to-skin Contact
Investigation of the Effects of Early Skin-to-Skin Contact on Mother and Baby in Cesarean Births
The rate of cesarean birth continues to increase in the world and in our country. As with all surgeries, the risks of cesarean birth include the possibility of bleeding and infection, prolonged recovery time after birth, delays…
- Trial name
- NCT07111949
- Testing
- SSC Group 1 (Operation room), SSC Group 2 (Post-operation room)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Musculoskeletal Pain
Pain Catastrophizing as a Cause for Systemic Inflammation
Research shows that the immune system is involved in chronic pain. The immune system is involved in the process of inflammation.
- Trial name
- NCT00823147
- Testing
- Pain Catastrophizing Induction
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Beth Darnall, PhD
Stress, Eating Behavior
Stress Reactivity Study in Adolescents
The goal of this study was to examine the glucocorticoid and behavioral responses to a psychological stressor in obese African-American and non-Latino white adolescents.
- Trial name
- SRAS (NCT03997149)
- Testing
- Acute Laboratory Stressor, Low affect video
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Posttraumatic Stress Disorder
The Role of Exercise in the Treatment of PTSD Symptoms
This is an 8-week experimental, repeated-measures clinical trial randomizing 120 Service Members with symptoms of PTSD into one of four groups: 1) imaginal exercises of exposure therapy only, 2) aerobic exercise only, 3) imaginal…
- Trial name
- NCT02649127
- Testing
- imaginal therapy, exercise, self-care
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The University of Texas Health Science Center at San Antonio