Clinical trials: Hydrocortisone
Asthma
Study of the Effect of Mometasone Furoate/Formoterol (MF/F), Montelukast and Beclomethasone Dipropionate (BDP) on Plasma Cortisol Levels of Children 5-11 Years Old With Persistent Asthma (P05574)
The purpose of this study is to assess the effect of one of five possible study medications used in the treatment of asthma on blood plasma cortisol levels in children aged 5-11 years with persistent asthma.
- Trial name
- NCT01615874
- Testing
- MF/F Metered Dose Inhaler (MDI) 25/5 mcg, MF/F MDI 50/5 mcg, MF/F MDI 100/5 mcg
- Sponsor
- Organon and Co
Granuloma, Tracheostomy
Treatment of Tracheostomy Granulomas
This study plans to learn more about the different ways used to treat tracheostomy granulomas. Investigators want to see which standard of care method (steroid application, silver nitrate, or betadine) is more successful in…
- Trial name
- NCT02116608
- Testing
- Betadine, Silver Nitrate, Hydrocortisone Butyrate Cream, 1.0%
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Endocrine Disease, Diabetes
Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults
Background: Metabolic syndrome is a name given to a group of factors that tend to occur together. These risk factors include central obesity (extra weight around the middle of the body) and high blood pressure and blood sugar…
- Trial name
- NCT01419535
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cardiac Arrest
Arterial Pressure and Stress-Dose Steroids in Cardiac Arrest.
Early stress-dose steroids are of uncertain efficacy in cardiac arrest. The current authors plan to conduct a pertinent mediation analysis using prospectively collected data from 2 prior randomized clinical trials of in-hospital…
- Trial name
- NCT02785224
- Testing
- Vasopressin Steroids Epinephrine
- Where
- 3 sites in Greece
- Sponsor
- University of Athens
Transsexualism
Observational Study on Metabolism and Psychopathology in Transsexual Patients
Gender identity disorders (also known as transsexualism) is defined as a condition in which a person with apparently normal somatic sexual differentiation is convinced that he or she is actually a member of the other sex.
- Trial name
- NCT02185274
- Where
- 3 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Other Preterm Infants
Use of Topical Lidocaine to Reduce Pain in Preterm Infants Receiving Nasal CPAP Continuous Positive Airway Pressure
The main purpose of this study is to evaluate the relative efficacy of topical lidocaine on reducing pain associated with the application of nasal CPAP in preterm infants
- Trial name
- NCT02268968
- Testing
- Lidocaine 2% Gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Adrenal Insufficiency
Effects of Steroid Replacement Therapy on Metabolic, Cardiovascular and Bone Outcomes in Adrenal Insufficiency
The current study is a randomized, open study aimed to compare the effects of conventional glucocorticoid replacement treatment and dual-release hydrocortisone on anthropometric, metabolic, cardiovascular and bone outcomes in…
- Trial name
- NCT06260462
- Testing
- dual-release hydrocortisone, Conventional glucocortidois
- Volunteers
- 88 people
- Sponsor
- University of Palermo
Adrenal Insufficiency
Prevalence of Adrenal Insufficiency in Kidney Transplanted Patients in Glucocorticoid Treatment
The primary purpose of this study is to determine the prevalence of adrenal insufficiency in a population of patients with kidney transplants receiving low dose prednisone treatment.
- Trial name
- NCT03136562
- Testing
- Synacthen test
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Bronchopulmonary Dysplasia
Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia
OBJECTIVES: I. Estimate the efficacy of cortisol replacement therapy during the first 12 days of life for prevention of bronchopulmonary dysplasia. II.
- Trial name
- NCT00004669
- Testing
- hydrocortisone
- Volunteers
- 40 people
- Sponsor
- National Center for Research Resources (NCRR)
Atrial Fibrillation New Onset
Combined Use of Dexmedetomidine and Hydrocortisone to Prevent New Onset AF After CABG Surgery
Atrial fibrillation (AF) occurs in 20% to 40% of patients after Coronary artery bypass grafting (CABG) and is associated with numerous detrimental sequelae.
- Trial name
- NCT05674253
- Testing
- Dexmedetomidine + Hydrocortisone
- Where
- Egypt
- Volunteers
- 248 people
- Sponsor
- Ain Shams University
Reward Value Level
Stress and Anxiety Effects on Valuation
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes.
- Trial name
- NCT07252947
- Testing
- Socially Evaluated Cold Pressor Task (SECPT), Non-Stressful Control Task
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Septic Shock, Acute Adrenal Insufficiency
Adrenal Insufficiency in Septic Shock
Randomized controlled trial evaluating the duration of steroid replacement therapy in patients with adrenal insufficiency and septic shock.
- Trial name
- NCT00842933
- Testing
- Corticosteroid
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Methodist Hospital Research Institute
Resilience, Burnout
Effects of a Connection-Enhancement Program for Newly Employed Generation Z Nurses.
The purpose of this randomized controlled trial is to evaluate the effects of a connection-enhancement program on resilience, perceived stress, burnout, and intention to stay among newly employed Generation Z nurses in a military…
- Conditions
- Resilience, Burnout, Occupational Stress, Newly Employed Nurses
- Trial name
- NCT07832357
- Testing
- Connection-Enhancement Program, Conventional Orientation Education
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Defense Medical University, Taiwan
Adrenal Insufficiency, Congenital Adrenal Hyperplasia
Dynamic Hormone Diagnostics in Endocrine Disease
The study will investigate 27 hour profiles of hormones in the subcutaneous tissue of healthy subjects and patients with Addison's, Congenital Adrenal Hyperplasia, Growth Hormone Deficiency, acromegaly, Cushings and Primary…
- Conditions
- Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Cushing Syndrome, Growth Hormone Deficiency
- Trial name
- ultradian (NCT02934399)
- Testing
- 27 hour subcutaneous fluid sampling
- Where
- 4 sites in Greece, Norway and 2 more
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Burns
Large Burn Outcome Study
To examine long term physical and psychosocial outcomes of pediatric burn survivors. We want to learn about thoughts, feelings, coping style, social support, and overall adjustment following burn injury.
- Trial name
- LBO (NCT00731887)
- Testing
- Blood and urine testing
- Sponsor
- The University of Texas Medical Branch, Galveston
Mild Autonomous Cortisol Excess
An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women
The purpose of this research study is to determine if treatment with Elagolix will improve body weight, waist circumference, muscle strength, cortisol secretion, blood glucose, cholesterol, and bone quality as well as mood and…
- Trial name
- NCT05038878
- Testing
- Elagolix
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Liver Cirrhosis
Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis
The main goal of the study is to investigate the clinical relevance, efficacy and safety of treating hypotensive cirrhotic patients with suspicion of sepsis and on vasopressors with low-dose hydrocortisone in order to reverse…
- Trial name
- SCOTCH; (NCT02602210)
- Testing
- Hydrocortisone, NaCL 0.9%
- Where
- 10 sites in Belgium, Czechia and 5 more
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostate Cancer
Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer
RATIONALE: Antiandrogen withdrawal may be an effective treatment for prostate cancer. PURPOSE: Randomized phase III trial to study the effectiveness of ketoconazole and hydrocortisone for antiandrogen withdrawal in treating men…
- Trial name
- NCT00002760
- Testing
- ketoconazole, therapeutic hydrocortisone, Withdrawal of antiandrogen therapy
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Immediate Dental Implant
Immediate Implants in the Aesthetic Zone
The use of immediate implants in the aesthetic area is a technique widely used in modern implantology. The characteristics of the patient, the implant, and the surgical procedure used may influence the final results.
- Trial name
- NCT04343833
- Testing
- Immediate dental implants
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
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