Clinical trials: Hydrocortisone
Child Development, Child Behavioral Problems
LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT
The LOVING study is a randomized controlled trial designed to determine whether adaptations to an internationally recognized parenting program that enhances sensitive caregiving likewise improves sensitive caregiving in Singapore…
- Conditions
- Child Development, Child Behavioral Problems, Parent Child Relationship
- Trial name
- LOVING (NCT07687524)
- Testing
- VIPP-SD-SingH, "Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component", CARE-SD, "Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline", NeuroEducation for Parents
- Where
- 5 sites in Singapore
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Dry Eye Syndromes
Effect of Ciclosporin Eyedrops on Sjögren Syndrome
Keratoconjunctivitis sicca, also known as dry eye syndrome, is one of the most common ophthalmological diseases and is treated with tear substitutes to moisten the surface of the eye and, in more severe cases of this disease…
- Trial name
- NCT04597762
- Testing
- Cyclosporin, Hydrocortisone
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Hospital Hietzing
Septic Shock
Steroids, Thiamine and Ascorbic Acid in Septic Shock
The objective of this project is to determine if in patients admitted to the hospital with septic shock (population), does treatment with a bundle including hydrocortisone, thiamine, and ascorbic acid improve in-hospital or…
- Trial name
- STASIS (NCT04134403)
- Testing
- STASIS
- Volunteers
- 80 people
- Sponsor
- Baqiyatallah Medical Sciences University
Low Back Pain
Effects of Yoga Versus Passive Modality on Pain, Disability, Salivary Cortisol Concentrations, Brain- Derived Neurotropic Factor, Heart Rate Variability and Immune Functions Among Patients With Chronic Low Back Pain: A Randomized Controlled Trial
This study may clarify a potential promising mechanism and clearest evidence to support the value of yoga as a therapeutic option for reducing chronic low back pain.
- Trial name
- NCT02244645
- Testing
- passive modality, Yoga treatment
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Congenital Adrenal Hyperplasia
COrticosteroid in Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia (CAH) results from a deficiency of a key enzyme in the biosynthesis of cortisol, mainly 21-hydroxylase, resulting in its classic form a neonatal salt loss syndrome and / or a virilization syndrome…
- Trial name
- COCA (NCT02552251)
- Testing
- Hormonal balance measurements, metabolic balance measurements, bone balance measurements
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Infections, Cardiac Arrest
Steroids and Post-resuscitation Infectious (Septic) Complications
Postresuscitation disease is characterized by post-insult systemic inflammation, adrenal insufficiency, and circulatory failure.
- Trial name
- NCT02408939
- Testing
- Stress-dose hydrocortisone
- Where
- 5 sites in France, Greece
- Volunteers
- 191 people
- Sponsor
- University of Athens
Postoperative Pain, Subcostal Transversus Abdominis Plane Block
Effects of Subcostal TAP Block and Local Anesthetic Infiltration After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy surgery is an intra-abdominal surgery that is frequently used in the treatment of gallbladder-related pathologies.
- Conditions
- Postoperative Pain, Subcostal Transversus Abdominis Plane Block, Gall Bladder Disease
- Trial name
- NCT05769881
- Testing
- Ultrasound guided subcostal transversus abdominis plane block, Wound site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Lymphoma, B-cell, Lymphoma, Non-Hodgkin
Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT
The purpose of this study is to determine if double autologous then allogeneic hematopoietic cell transplant may offer an improved treatment option for patients with relapsed diffuse large B-cell lymphoma (DLBCL) who are not…
- Conditions
- Lymphoma, B-cell, Lymphoma, Non-Hodgkin, Diffuse Large B-cell Lymphoma (DLBCL), Malignant Lymphoma, Non-Hodgkin
- Trial name
- NCT00482053
- Testing
- Autologous hematopoietic stem cell transplantation (auto-HSCT), Allogeneic hematopoietic stem cell transplantation (allo-HSCT), Total lymphoid irradiation (TLI)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Cancer, Stress, Psychological
Brief Mindfulness Chatbot Intervention for Cancer Patients
This study tests a new digital tool for hospitalized cancer patients. The tool is a chatbot on LINE, a popular messaging app. The chatbot is called Mindbot. Mindbot leads a 10-minute mindfulness practice each day.
- Trial name
- MINDBOT-CA (NCT07811739)
- Testing
- Mindbot: Brief Mindfulness-Based LINE Chatbot with Virtual Reality
- Volunteers
- 66 people
- Sponsor
- Taipei Medical University
Stress Reaction, Behavior, Social
The Effects of Therapy Dogs on Child Biology and Behavior
The objective of this study is to apply a rigorous experimental design to test whether children's interactions with therapy dogs increase immediate prosocial behavior and reduce immediate biological response to stress.
- Trial name
- NCT03949569
- Testing
- Therapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Leukemia
Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002805
- Testing
- filgrastim, cladribine, cytarabine
- Where
- 38 sites in United States, Australia and 1 more
- Volunteers
- 115 people
- Sponsor
- Children's Oncology Group
Sedentary Behavior, Acute Exercise
Acute Endocrine Responses to Aerobic and Anaerobic Exercise in Sedentary Women: A Comparative Analysis of Thyroid Hormones and Cortisol
This study aims to compare acute thyroid hormone and cortisol responses to aerobic and anaerobic exercise in sedentary women. Thirty sedentary women aged 18-25 years will voluntarily participate in the study.
- Conditions
- Sedentary Behavior, Acute Exercise, Endocrine Response
- Trial name
- AERAE (NCT07823335)
- Testing
- 20-Meter Shuttle Run Test, Wingate Anaerobic Test
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Assoc. Prof. Dr. Özgür EKEN
Osteoarthritis
Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men
This study will examine the effects of morphine on leuteinizing hormone, testosterone, adrenocorticotropic hormone and cortisol in men.
- Trial name
- NCT00088296
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
This phase II trial tests the addition of venetoclax and/or blinatumomab to usual chemotherapy for treating infants with newly diagnosed acute lymphoblastic leukemia (ALL) with a KMT2A gene rearrangement (KMT2A-rearranged [R]) or…
- Trial name
- NCT06317662
- Testing
- Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Blinatumomab
- Where
- 117 sites in United States, Puerto Rico
- Volunteers
- 153 people
- Sponsor
- National Cancer Institute (NCI)
Dementia
Effects of Snoezelen Multisensory Therapy on Older Adults With Dementia
This randomized, controlled, longitudinal clinical trial investigates the effects of Snoezelen Multisensory Therapy (SMT) as an adjunct to standard therapy (ST) in older adults with dementia.
- Trial name
- SMT (NCT07657208)
- Testing
- Snoezelen Multisensory Therapy, Standard Therapy
- Where
- Slovenia
- Volunteers
- 63 people
- Sponsor
- University of Primorska
Stroke, Stroke, Acute
Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke
The primary objective of this study is to determine the efficacy of a single intravenous infusion of unrelated donor umbilical cord blood (UCB) for improving functional outcomes in patients with ischemic stroke.
- Conditions
- Stroke, Stroke, Acute, Brain Injury, Acute
- Trial name
- CoBIS 2 (NCT03004976)
- Testing
- Umbilical Cord Blood
- Where
- 6 sites in United States
- Volunteers
- 79 people
- Sponsor
- Joanne Kurtzberg, MD
Head and Neck Neoplasms
Radiotherapy Related Skin Toxicity: Mepitel® vs. Standard Care in Patients With Locally Advanced Head-and-Neck Cancer
The aim for the present study named RAREST (RAdiotherapy RElated Skin Toxicity) is to compare the new dressing with the standard skin care.
- Trial name
- RAREST-01 (NCT03047174)
- Testing
- Mepitel® Film, Standard Care
- Where
- 2 sites in Germany
- Volunteers
- 57 people
- Sponsor
- University Hospital Schleswig-Holstein
Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
This is a phase I study of temsirolimus (Torisel) combined with dexamethasone, cyclophosphamide and etoposide in patients with relapsed acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL) or peripheral T-cell lymphoma…
- Conditions
- Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma, Peripheral T-cell Lymphoma
- Trial name
- NCT01614197
- Testing
- Temsirolimus, Etoposide, Cyclophosphamide
- Where
- 32 sites in United States, Australia and 1 more
- Volunteers
- 16 people
- Sponsor
- Therapeutic Advances in Childhood Leukemia Consortium
Stress
Physical and Mental Load in the Surgeon Performing Laparoscopic Tasks
The surgeons load during laparoscopic surgery is still unclear. Laparoscopic surgery is more demanding because of the challenge of operating through small scars in the abdominal wall without any tactile feedback depending only on…
- Trial name
- NCT00311285
- Testing
- Electrogram (EMG), heart rate variability (HRV), salivary cortisol, goniometry, inclinometry
- Where
- 2 sites in Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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