Clinical trials: Hydrocortisone, completed
Postoperative Nausea and Vomiting
The Effect of Prophylactic Antiemetic Dexamethasone on Plasma Cortisol Levels
Dexamethasone is a synthetic corticosteroid that has been proven to be effective and relatively safe for the prophylaxis of the postoperative nausea and vomiting (PONV).
- Trial name
- NCT01524731
- Testing
- Saline, Dexamethasone
- Where
- 2 sites in Canada
- Volunteers
- 63 people
- Sponsor
- William Li Pi Shan
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Mucormycosis; Pulmonary (Etiology)
Amphotericin Versus Posaconazole for Pulmonary Mucormycosis
Pulmonary mucormycosis is a serious illness with high morbidity and mortality (approximately 57%). Surgery and antifungal therapy are central in the management of mucormycosis.
- Trial name
- NCT05468372
- Testing
- Posaconazole 600 mg followed by posaconazole 300 mg once daily, Liposomal Amphotericin B
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Postoperative Pain, Subcostal Transversus Abdominis Plane Block
Effects of Subcostal TAP Block and Local Anesthetic Infiltration After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy surgery is an intra-abdominal surgery that is frequently used in the treatment of gallbladder-related pathologies.
- Conditions
- Postoperative Pain, Subcostal Transversus Abdominis Plane Block, Gall Bladder Disease
- Trial name
- NCT05769881
- Testing
- Ultrasound guided subcostal transversus abdominis plane block, Wound site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Atopic Dermatitis
Equivalence of the Response to Vaccination of Tacrolimus Ointment to a Steroid Ointment Regimen in Children With Atopic Dermatitis
Seven-month study in pediatric patients (2-11 years) with moderate to severe AD who were considered to benefit from vaccination to prevent invasive disease caused by Neisseria meningitides serogroup C.
- Trial name
- NCT00801957
- Testing
- tacrolimus ointment 0.03%, hydrocortisone acetate ointment 1%, hydrocortisone butyrate ointment 0.1%
- Where
- 36 sites in Australia, Belgium and 6 more
- Volunteers
- 260 people
- Sponsor
- Astellas Pharma Inc
Patient Admitted in Reanimation
Hydrocortisone Use After Etomidate in Intensive Care
the objective of the study is to assess the value of substitution with 200mg/24h of hydrocortisone for 48 hours for patients in intensive care who have received a single injection of etomidate
- Trial name
- NCT00862381
- Testing
- Hydrocortisone
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Grenoble
Addison Disease
A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT)
DOSCORT is a 2-dose, cross-over study primarily aiming to identify and validate novel biological markers (biomarkers) of glucocorticoid effect in the human body.
- Trial name
- NCT03210545
- Testing
- Betamethasone
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Healthy
Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans
The purpose of this study is to investigate the effect of hydrocortisone on glucose-induced insulin secretion and sensitivity, by means of an intravenous glucose tolerance test with frequent sampling (FSIGT) followed by minimal…
- Trial name
- NCT00709839
- Testing
- Hydrocortisone, Glucose 33%
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Congenital Adrenal Hyperplasia
Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia
This phase III study is an open-label extension study to be conducted at approximately 21 investigational sites across 3 countries.
- Trial name
- NCT05299554
- Testing
- Chronocort
- Where
- 21 sites in United States, France and 1 more
- Volunteers
- 76 people
- Sponsor
- Immedica Pharma AB
Asthma
Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room
To compare the efficacy and safety of inhaled procaterol (Meptin Air) versus inhaled salbutamol as metered dose inhaler (MDI) reliever of acute exacerbation of asthma not in imminent respiratory failure.
- Trial name
- NCT01091337
- Testing
- Procaterol, Salbutamol
- Where
- Philippines
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical, Inc., Philippines
Pregnancy Related, Obesity, Childhood
OBEAT - Beating Obesity
The primary objective of this trial is to study the feasibility of a resilience intervention to reduce stress and thus improve sleep, healthy diet and physical activity in normal weight pregnant women.
- Conditions
- Pregnancy Related, Obesity, Childhood, Stress
- Trial name
- NCT03854331
- Testing
- Resilience program
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Leukemia
Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002805
- Testing
- filgrastim, cladribine, cytarabine
- Where
- 38 sites in United States, Australia and 1 more
- Volunteers
- 115 people
- Sponsor
- Children's Oncology Group
Major Depressive Episode
Stress Systems and Psychotherapy in Depression
Dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis as well as maladaptive activation of the autonomic nervous system (ANS) are discussed as relevant factors in the development of a major depressive episode and as a…
- Trial name
- Bio-COPE (NCT03752853)
- Testing
- internet-based intervention for mild to moderate depression
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Freie Universität Berlin
Psychological Stress, Academic Stress
Stress Reduction Program for Iraqi Medical Students
A 4-week stress reduction program for medical students during exams, measuring effects on stress, heart rate, blood pressure, and stress hormones (ACTH, cortisol, DHEA).
- Trial name
- SRIMS (NCT07451145)
- Testing
- Mindfulness-Based Stress Reduction Program
- Where
- Iraq
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Thi-Qar
Cushing's Syndrome
Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome
The purpose of this prospective, international phase III/IV study is to assess the efficacy and safety of metyrapone in patients with endogenous Cushing's syndrome during up to 36 weeks of treatment.
- Trial name
- PROMPT (NCT02297945)
- Testing
- metyrapone
- Where
- 36 sites in Belgium, Germany and 6 more
- Volunteers
- 50 people
- Sponsor
- HRA Pharma
Dermatologic Disease
A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
One of the most frequent skin conditions is atopic dermatitis (AD), characterized by its pruritic inflammation effect. Where the prevalence of AD increased in the last three decades by two or three folds worldwide, especially in…
- Trial name
- NCT05607901
- Testing
- Tacrolimus ointment, Hydrocortisone 1% cream
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Anxiety, Heart Diseases
Reiki Effects on Heart Rhythm, Biochemistry and Cortisol Findings, and Anxiety
This study aimed to investigate the effects of Reiki, which is a complementary and traditional method, on heart rhythm, biochemistry and cortisol findings, and anxiety in individuals with arrhythmia.
- Trial name
- NCT05483842
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara Medipol University
Sepsis, Septic Shock
Days Alive and Out of Hospital for Patients With Sepsis
We will perform a retrospective cohort study to assess the construct validity and performance of days alive and out of hospital at day 90 (DAOH90) in cohorts of patients with sepsis and septic shock who have been included in…
- Trial name
- NCT04567433
- Testing
- Hydroxyethyl starch, Hydrocortisone, Early Goal Directed Therapy
- Where
- Australia
- Volunteers
- 6,213 people
- Sponsor
- The George Institute for Global Health, Australia
Healthy Young Adults
The Association Between the Stress Hormone Cortisol and Decision-making
The goal of this study is to learn how acute psychosocial stress influences decision-making in healthy young adults. It will also examine whether cortisol reactivity, a biological stress response, changes the influence of…
- Trial name
- NCT07702747
- Testing
- Trier Social Stress Test
- Where
- Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Marie-France Marin
Atopic Dermatitis
Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis
The purpose of this research study is to better understand adherence to Locoid when people use it to treat atopic dermatitis.
- Trial name
- NCT00693693
- Testing
- hydrocortisone 17-butyrate 0.1% Cream preparation, hydrocortisone 17-butyrate 0.1% Ointment preparation, hydrocortisone 17-butyrate 0.1% Lipocream preparation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University