Clinical trials: Hydrocortisone
Acute Asthma
Nebulized Budesonide Combined With Systemic Corticosteroid in Acute Severe Asthma
Our study is a prospective double-blind randomized study performed in the Emergency Department (ED). The objective of our study was to demonstrate the additive effect of high and repeated doses of inhaled budesonide combined with…
- Trial name
- NCT04016220
- Testing
- Budesonide, normal saline
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University of Monastir
Type 1 Diabetes
Risk Factors of Metabolic Control in Children and Adolescents With Type 1 Diabetes
Background: Type 1 diabetes is one of the most common chronic illnesses among children and adolescents. Although, intensive medical care is provided for these patients, some of them have poor metabolic control.
- Trial name
- NCT03642470
- Where
- Switzerland
- Volunteers
- 197 people
- Sponsor
- University Children's Hospital, Zurich
Diabetes Mellitus, Type I Diabetes
The Effect of Mindfulness Based Stress Reduction in Patients With Painful Diabetic Peripheral Neuropathy
By 2020, it is estimated that 3.7 million Canadians will have diabetes mellitus, with type 2 diabetes (T2DM) accounting for more than 90% of cases.
- Conditions
- Diabetes Mellitus, Type I Diabetes, Type II Diabetes, Diabetic Peripheral Neuropathy
- Trial name
- AWARE (NCT02127762)
- Testing
- Mindfulness Based Stress Reduction
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Ulcerative Colitis
A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis
PHASE : IV TYPE OF STUDY : With direct benefit. DESCRIPTIVE : Multicentre, randomized, open label study. INCLUSION CRITERIA : Acute severe ulcerative colitis.
- Trial name
- ACTIVE (NCT02425852)
- Testing
- Azathioprine, Infliximab, Prednisolone
- Where
- 16 sites in France
- Volunteers
- 65 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Newborn; Vitality, Sleep
Effects of Kangaroo Care on Circadian Rhythm, Growth and Physiological Effects
This study was planned to investigate the effect of premature babies receiving regular kangaroo care in the NICU on circadian rhythm, growth and physiological parameters, and breast milk cortisol levels
- Conditions
- Newborn; Vitality, Sleep, Preterm Labor, Care Pattern, Maternal
- Trial name
- NCT06589349
- Testing
- Kangaroo Care
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Sibel Küçükoğlu
Sepsis, Septic Shock
Cortisol Levels and Mortality in Septic Shock ICU Patients
This prospective observational study aims to evaluate the prognostic value of cortisol levels and their dynamic changes in critically ill patients with sepsis and septic shock admitted to the intensive care unit.
- Trial name
- NCT07582926
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Ankara Etlik City Hospital
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
The Impact of Holding on Stress and Bonding in Mother-Infant Pairs During Therapeutic Hypothermia
This research is being done to try to improve the experience of mothers and babies during therapeutic hypothermia. Currently, mothers are not able to hold their baby during hypothermia treatment.
- Trial name
- NCT03837717
- Testing
- Holding, Saliva collection, No Holding
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- MaineHealth
Other Diseases or Conditions
Mother-caregivers of Children With Duchenne Muscular Dystrophy
The incidence of Duchenne Muscular Dystrophy (DMD) is approximately 1 in 3.500 male newborns. During its progression there is loss of mobility, swallowing difficulties and a significant reduction in respiratory capacity.
- Trial name
- DMDK (NCT01921374)
- Testing
- sleep parameters, Hormonal profile, Inflammatory profile
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Levy Andersen
Mental Health Wellness
Recovery Strategies Based on Mindfulness and Physical Exercise on Levels of Stress and Inmunoglobulin A
The present study aims to compare the differential effects of mindfulness meditation (MBI) and physical exercise (PE) on different stress, academic performance and health variables (self-report means and biological measure of IgA…
- Trial name
- ERME-IgA (NCT05771649)
- Testing
- Mindfulness-based intervention, Physical exercise
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Sleep Restriction
Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction and 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with…
- Trial name
- NCT04037605
- Testing
- Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Postoperative Pain, Stress, Psychological
Effect Of Electroacupuncture With Local Anesthesia On Pain And Stress During Impacted Lower Third Molar Surgery
This randomized controlled trial investigates the effect of electroacupuncture as an adjunct to local anesthesia on perioperative pain and stress during ambulatory surgical extraction of impacted lower third molars.
- Conditions
- Postoperative Pain, Stress, Psychological, Impacted Lower Third Molar
- Trial name
- EASE (NCT07509294)
- Testing
- Electroacupuncture
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University of Zagreb
Cytomegalovirus Infection, Renal Transplant Failure
Efficacy and Safety of Induction Strategies Combined With Low Tacrolimus Exposure in Kidney Transplant Recipients Receiving Everolimus or Sodium Mycophenolate
Despite the improvement of efficacy results with current immunosuppressive regimens (about 15% of incidence of acute rejection), the security schemes used do not show the same results.The most worldwide used regime is tacrolimus…
- Conditions
- Cytomegalovirus Infection, Renal Transplant Failure, Transplant; Complication, Rejection
- Trial name
- NCT01354301
- Testing
- Thymoglobulin, Everolimus, Basiliximabe
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Hospital do Rim e Hipertensão
Diabetes Mellitus, Stress
Effect of Breathing and Relaxation Exercises on Serum Cortisol Levels in Type 2 Diabetic Patients
Background: Diabetes is a fast-growing health problem in Egypt with a significant impact on morbidity, mortality, and health care resources.
- Trial name
- NCT05231031
- Testing
- Aerobic exercise, breathing exercise, Relaxation training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Mild Autonomous Cortisol Secretion Adenoma, Non Secreting Adenoma
Ultradian Steroid Rhythms in Adrenal Incidentalomas
Twenty to 40% of adrenal incidentalomas are responsible for MACS (mild autonomous cortisol producing secretion). The biological tools used in current practice to explore MACS do not provide precise information on cortisol…
- Trial name
- CHRONOMACS (NCT07387419)
- Testing
- U-RYTHM system
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Anxiety Disorder, Depression
Minocycline Hydrochloride in Reducing Chemotherapy Induced Depression and Anxiety in Patients With Stage I-III Breast Cancer
This randomized clinical trial studies how well minocycline hydrochloride works in reducing chemotherapy induced depression and anxiety in patients with stage I-III breast cancer.
- Conditions
- Anxiety Disorder, Depression, Recurrent Breast Cancer, Stage IA Breast Cancer
- Trial name
- NCT02203552
- Testing
- minocycline hydrochloride, laboratory biomarker analysis, Questionnaire administration
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Atopic Dermatitis
Efficacy and Steroid Sparing Potential Study of DGLA Cream in Early Childhood Patients With Moderate to Severe Atopic Dermatitis
This study will investigate the steroid sparing potential of DS107E to vehicle in patients with moderate to severe atopic dermatitis.
- Trial name
- NCT03676933
- Testing
- DS107E, Vehicle, Hydrocortisone Butyrate 0.1% Cream
- Where
- Ireland
- Volunteers
- 5 people
- Sponsor
- DS Biopharma
Yohimbine, Hydrocortisone
The Role of Stress Neuromodulators in Decision Making Under Risk and Selective Attention to Threat
Incidental affective states, i.e., affective states can influence decision making and selective attention to threatening information.
- Conditions
- Yohimbine, Hydrocortisone, Yohimbine + Hydrocortisone, Placebo
- Trial name
- SID (NCT04359147)
- Testing
- "Yohimbine", "Hydrocortisone", "Yohimbine + Hydrocortisone"
- Where
- Germany
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Stroke Patients, Stroke
Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke
The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke.
- Conditions
- Stroke Patients, Stroke, Stroke; Sequelae, Young Adults
- Trial name
- NCT07019493
- Testing
- Observational Cohort
- Where
- 2 sites in Australia
- Volunteers
- 100 people
- Sponsor
- The Florey Institute of Neuroscience and Mental Health
Primary Hyperaldosteronism
Intraoperative Analysis of Cortisol During Adrenal Vein Sampling
Aldosterone is a hormone produced in the adrenals that helps regulate the salt balance and blood pressure. Primary hyperaldosteronism is one of the main endocrine causes of secondary hypertension.
- Trial name
- NCT01761344
- Testing
- Intraoperative cortisol measurement.
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- Haukeland University Hospital
Infant, Newborn, Hypotension
Hypotension in Neonates
This observational study collects information on the current incidence and management of hypotension in babies born at term or late preterm that are admitted to Neonatal Intensive Care Units (NICUs) within the Neonatal Research…
- Conditions
- Infant, Newborn, Hypotension, Blood Pressure
- Trial name
- NCT00882284
- Where
- 17 sites in United States
- Volunteers
- 820 people
- Sponsor
- NICHD Neonatal Research Network
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