Clinical trials: Hydrocortisone, completed
Multiple Sclerosis
Physical Therapy and Neuroactive Steroids Therapy Does Not Modulate Serum Level of Neuroactive Steroids
This study describes modulation of neuroproprioceptive facilitation and inhibition physical therapy on serum level of neuroactive steroids in multiple sclerosis.
- Trial name
- NCT04379193
- Testing
- Neuroproprioceptive facilitation and inhibition physical therapy
- Volunteers
- 63 people
- Sponsor
- Charles University, Czech Republic
Neonatal Hypotension
Early Use of Hydrocortisone in Hypotensive Very Low Birth Weight Infants
The purpose of this study is to investigate the early use of hydrocortisone in hypotensive very low birth weight infants. Based on the observations that: hypotension is a common problem in very low birthweight infants and is…
- Trial name
- NCT00358748
- Testing
- Hydrocortisone
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Sepsis, Septic Shock
Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
In this study, we aim to determine whether the combination of Ascorbic Acid (Vitamin C), Thiamine (Vitamin B1), and Corticosteroids improves the trajectory of organ failure and reduces mortality in patients with sepsis and septic…
- Conditions
- Sepsis, Septic Shock, Metabolic Disturbance
- Trial name
- NCT03389555
- Testing
- vitamin C, vitamin B1, hydrocortisone, Normal saline
- Where
- 13 sites in United States
- Volunteers
- 205 people
- Sponsor
- Beth Israel Deaconess Medical Center
Peri-implantitis, Peri-implant Mucositis
Peri-Implant Sulcus Fluid Stress Markers in Health and Disease
This study examines the association between psychosocial stress and peri-implant diseases. Peri-implant diseases are inflammatory conditions affecting the tissues around dental implants and may contribute to implant failure.
- Conditions
- Peri-implantitis, Peri-implant Mucositis, Peri-Implant Health
- Trial name
- NCT07353515
- Testing
- Psychological Assessment, Peri-implant Sulcular Fluid Biomarker Analysis, Peri-implant Clinical Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Inonu University
Atopic, Dermatitis
Tacrolimus Versus Hydrocortisone in Atopic Dermatitis
Atopic dermatitis (AD) is a very common inflammatory, genetic skin disorder that occurs more frequently in children. Its exact etiology is not known but it is characterized by pruritic skin reactions with elevation in the levels…
- Trial name
- NCT05324618
- Testing
- Tacrolimus, Hydrocortisone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Suprascapular Nerve Block, Axillary Nerve Block
The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block
Suprascapular nerve block (SSNB) is most commonly used for relieving postoperative pain of arthroscopic rotator cuff repair and it can be used in combination with axillary nerve block (ANB).
- Conditions
- Suprascapular Nerve Block, Axillary Nerve Block, Dexmedetomidine, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04398589
- Testing
- Dexmedetomidine injection, Saline injection
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Lymphoblastic Lymphoma
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
This is a phase II clinical trial using risk-adapted therapy. The treatment is acute lymphoblastic leukemia (ALL)-based therapy, using multi-agent regimens comprising of induction, consolidation, and continuation (maintenance)…
- Trial name
- NCT01451515
- Testing
- Prednisone, Vincristine, Daunorubicin
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- St. Jude Children's Research Hospital
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteopathic Manipulative Treatment
Osteopathic Sympathetic Harmonization and Depression
Depression appears to be resistant to the available pharmacological treatments. Autonomic responses accompanied by any psychological stress are sympathetic nervous system (SNS) and neuroendocrine responses are formed by…
- Trial name
- NCT04840043
- Testing
- Osteopathic sympathic harmonization
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Cumhuriyet University
Psychological Stress
Moderating Impact of Various Emotion Personality Factors on Salivary Cortisol Response to a TSST
With the aim of evaluating the putative impacts of emotion related personality factors on physical and mental disease and the mechanisms of these impacts, 58 students were submitted to a social stress test (Trier Social Stress…
- Trial name
- cortpersonal (NCT00451126)
- Where
- Belgium
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Depression
The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression
There is good evidence to suggest that the pathological version of sadness that people with Major Depression experience could be caused by the failure of the hormone cortisol to properly inhibit sadness-related brain activity in…
- Trial name
- NCT02837432
- Testing
- Hydrocortisone acetate
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Stanford University
Apparent Mineralocorticoid Excess
An Investigation Into the Effect of Liquorice Ingestion on the Salivary Cortisol to Cortisone Molar Ratio
Aldosterone, the major mineralocorticoid hormone and cortisol, the major glucocorticoid hormone are produced in the adrenal gland.
- Trial name
- NCT02939144
- Testing
- Liquorice
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Dental Implants, Peri-Implant Tissues
CTG vs VCMX for Peri-implant Soft Tissue Thickness
This investigator-initiated randomized controlled clinical trial evaluated changes in peri-implant soft tissue thickness in the aesthetic zone following soft tissue augmentation.
- Conditions
- Dental Implants, Peri-Implant Tissues, Missing Tooth/Teeth
- Trial name
- NCT07324187
- Testing
- Connective Tissue Graft, Volume-Stable Collagen Matrix
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical Innovation Center Wroclaw
B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
This pilot, phase II trial studies the side effects of giving bortezomib together with combination chemotherapy and to see how well it works in treating young patients with relapsed acute lymphoblastic leukemia or lymphoblastic…
- Conditions
- B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma
- Trial name
- NCT00873093
- Testing
- L-asparaginase, doxorubicin hydrochloride, therapeutic hydrocortisone
- Where
- 171 sites in United States, Australia and 2 more
- Volunteers
- 148 people
- Sponsor
- National Cancer Institute (NCI)
Anesthesia, Infertility
Sevoflurane Versus Propofol; Neuro Endocrine Response in Patients of Oociyt Pick up
Patients in the study will be grouped as 1st group Propofol, 2nd Group Sevofluran.Preoperative blood will be taken from the patients and cortisol, acth, glucagon, aldosterone, PGE2, CRH will be studied.
- Conditions
- Anesthesia, Infertility, Pain, Postoperative, Stress, Psychological
- Trial name
- NCT03507621
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Orak
Hypertension
A Study to Evaluate the Effects of LCI699 on Cortisol in Participants With Hypertension
This study determined the maximum dose of LCI6999 with respect to effect on the ACTH-stimulated cortisol response in participants with hypertension.
- Trial name
- NCT00817414
- Testing
- LCI699
- Where
- 11 sites in United States, Iceland
- Volunteers
- 63 people
- Sponsor
- Novartis
Effects of Meditative Movement on Body Composition
The Move Well Study
This study will explore the effects of meditative movement on body composition in a group of 60 midlife women. Women will participate in 30-minute meditative movement (MM) classes for an eight-week period.
- Trial name
- MW (NCT04072133)
- Testing
- Meditative Movement
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Ischemic Stroke, Cortisol; Hypersecretion
Neuroactive Steroids in Acute Ischemic Stroke
Acute ischemic stroke (AIS) represents an economical challenge for health systems all over the globe. Despite increasing knowledge of the pathophysiology of AIS, there is no satisfactory treatment to revert the resulting brain…
- Trial name
- Cortisol (NCT03242304)
- Testing
- Behavioral tests
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Militar Central, Argentina
Oral SubMucous Fibrosis
Evaluation of Efficacy of Aloevera in the Treatment of Oral Submucous Fibrosis- A Clinical Study
Oral submucous fibrosis is a chronic, insidious disease caused by arecanut use and is associated with both significant morbidity (including burning sensation and reduced oral opening) and an increased risk of malignancy.
- Trial name
- NCT02714543
- Testing
- aloevera juice, Hydrocortisone, Hyaluronic Acid
- Volunteers
- 74 people
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India
Anxiety
The Effect of Aromatherapy Applied to the Patients in the Urodynamic Procedure
This randomized controlled study is planned to determine the effect of aromatherapy applied to patients in the urodynamic procedure on patients' anxiety and serum cortisol levels.
- Trial name
- NCT05255874
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mersin University