Clinical trials: Hydrocortisone, completed
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Longitudinal Study of Cortisol and Pulmonary Function
To conduct a longitudinal study of the relationship between the rate of decline of pulmonary function and measurements of cortisol concentration and excretion in a sample of middle-aged and older men and their wives.
- Trial name
- NCT00005370
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Opiate
Effects of Diacetylmorphine (DAM) on Brain Function and Stress Response
The aims of the study are to investigate the effects of diacetylmorphin (heroin) on brain using functional magnetic resonance imaging (fMRI), coupled with measurements of cortisol concentrations and neurophysiological stress…
- Trial name
- NCT01174927
- Testing
- diacetylmorphine (DAM)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoporosis, Bullous Pemphigoid
Influence of Dermocorticoids on Bone Mineral Density in Patients With Bullous Pemphigoid
Bullous pemphigoid is the most common type of bullous skin disease and is clinically characterized by clear-tense bullae, which result in post-bullous cutaneous erosions, altering the skin barrier.
- Trial name
- DERMOS (NCT03926377)
- Testing
- bone densitometry, blood test, radiographs of the thoracic and lumbar spine
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Premature Baby 33 to 36 Weeks, Mother-Infant Interaction
A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact (PRCTS2S)
Late preterm infants are at risk of experiencing inadequate glycogen stores with immature glucose metabolism and increased adenosine triphosphate (ATP) degradation, which indicates cellular increased and stress.
- Conditions
- Premature Baby 33 to 36 Weeks, Mother-Infant Interaction, Oxidative Stress
- Trial name
- PRCTS2S (NCT04368767)
- Testing
- Skin-to-skin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Adult Male Volunteers
Evaluation of Systemic Bioavailability and Effects on 24-Hour Plasma Cortisol Profile of 6 mg Delivered Once Daily Versus 3 mg Delivered Twice Daily in Healthy Adult Male Volunteers
Single-centre, randomized, double-blind, two-period, two-sequence, cross-over 7-day study. This study is the first safety/tolerability evaluation of a product -suppository formulation containing 6 mg BDP (once daily dosing), a…
- Trial name
- NCT04873063
- Testing
- Beclomethasone dipropionate
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- SOFAR S.p.A.
Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
This phase III trial studies combination chemotherapy with or without lestaurtinib with to see how well they work in treating younger patients with newly diagnosed acute lymphoblastic leukemia.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia, Childhood T Acute Lymphoblastic Leukemia
- Trial name
- NCT00557193
- Testing
- Asparaginase, Biospecimen Collection, Bone Marrow Biopsy
- Where
- 170 sites in United States, Australia and 2 more
- Volunteers
- 218 people
- Sponsor
- Children's Oncology Group
Insulin Resistance
Hormonal Mechanisms of Sleep Restriction
The purpose of this study is to study the effects of sleep restriction on the production of two hormones, cortisol and testosterone.
- Trial name
- NCT02256865
- Testing
- Ketoconazole, Hydrocortisone, Testosterone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Substance Abuse Disorders
Study of Smoking Abstinence
Background: Relapse following cigarette abstinence remains a common problem for smokers who are attempting to quit. Most research has focused on the acute withdrawal phase that occurs within the first 48 hours to 1 week after…
- Trial name
- NCT01035632
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Premature Birth of Newborn
Neuroendocrine Mechanisms of Developmental Massage Therapy (DMT) in Preterm Infants: Clinical Study
The purpose of this study is to see if daily massage therapy will help premature infants respond to stress better, as well as improve their growth and neurobehavioral development.
- Trial name
- DMT (NCT00722943)
- Testing
- Developmental Massage Therapy, no intervention
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of Utah
Psychological Distress
The Psychological Effect of the Covid-19 Pandemic
At the end of 2019, the novel coronavirus disease (Covid-19), which emerged in China, has become a public health emergency of international concern.
- Trial name
- NCT05503589
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Child Behavior Problem
Hair Cortisol and Symptoms in Children With Psychopathology During CBT
This study aims to examine the relationship between hair cortisol concentration and behavior and sleep disturbance symptoms in children with psychiatric disorders.
- Trial name
- NCT06274424
- Testing
- The Friends Program
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Adrenal Insufficiency
Effects of Steroid Replacement Therapy on Metabolic, Cardiovascular and Bone Outcomes in Adrenal Insufficiency
The current study is a randomized, open study aimed to compare the effects of conventional glucocorticoid replacement treatment and dual-release hydrocortisone on anthropometric, metabolic, cardiovascular and bone outcomes in…
- Trial name
- NCT06260462
- Testing
- dual-release hydrocortisone, Conventional glucocortidois
- Volunteers
- 88 people
- Sponsor
- University of Palermo
Prostate Cancer, Prostate Adenocarcinoma
Trilostane for Androgen-Independent Prostate Cancer
The main purpose of this study is to test the safety of trilostane by looking at what effects, good and bad, it has on patients with androgen-independent prostate cancer.
- Trial name
- NCT00181597
- Testing
- Trilostane, Hydrocortisone
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Genzyme, a Sanofi Company
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Cannabis Use Disorder
Cannabinoids and Biological Reactivity to Stress
The goal of this study is to test the impact of two drugs that produce temporary stress-like symptoms, both in isolation and together, on cannabis use motivation in individuals with Cannabis Use Disorder.
- Trial name
- COBRAS (NCT06430580)
- Testing
- Hydrocortisone Oral, Yohimbine Hydrochloride
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Florida State University
Depression
Depression, Adversity, and Stress Hormones (DASH) Study
The stress-related hormone cortisol has been studied in depression for decades. However, relatively little is known about the role of cortisol in psychological features of depression.
- Trial name
- DASH (NCT03195933)
- Testing
- Cortisol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Frail Elderly Persons
SUPPORT FOR FRAIL ELDERLY PERSONS - From Prevention to Palliation
The present study "Elderly person in the risk zone" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www.
- Trial name
- NCT00877058
- Testing
- preventive home visit, senior meetings
- Where
- Sweden
- Volunteers
- 459 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Community Acquired Pneumonia
Corticosteroids in Community Acquired Pneumonea
Low dose hydrocortisone IV in patients with CAP fastens recovery of pneumonia and prevents the development of sepsis related complications with a significant reduction in duration of mechanical ventilation
- Trial name
- NCT01228110
- Testing
- Hydrocortison, Saline Solution
- Volunteers
- 80 people
- Sponsor
- Cairo University
Mental Health Wellness 1
Onnit Labs New Mood Supplementation in Healthy College Students
The primary purpose of this study is to assess the effectiveness of ONNIT Lab's New Mood™ dietary supplement in supporting optimal mood balance and reducing daily stress among collegiate-aged men and women.
- Trial name
- NCT05109923
- Testing
- Multi-Ingredient Herbal Supplement
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Skin to Skin Contact, Newborn; Vitality
The Effect of Paternal Skin-to-Skin Contact on Neonatal Parameters
This study was planned to examine the effect of skin-to-skin contact between the babies of mothers who gave birth by cesarean section and their fathers on the physiological parameters and comfort of the newborn.
- Trial name
- NCT06956859
- Testing
- Paternal Skin to skin applicated to newborns
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi