Clinical trials: Hydrocortisone
Pregnancy, Stress
Effects of Stress on Glucose Tolerance During Pregnancy
The objective of the study is to investigate the effect of stress on glucose tolerance during pregnancy. The main objectives of the study are to investigate if various measures of stress (stressful life events, the perceived…
- Conditions
- Pregnancy, Stress, Gestational Diabetes
- Trial name
- NCT01707784
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Coronary Artery Disease, Valvular Heart Disease
The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
During induction for cardiac surgery, patient hemodynamic stability is achieved by using anesthetic drugs which least affects hemodynamics such as benzodiazepines, etomidate.
- Trial name
- NCT01495949
- Testing
- etomidate, thiopentone
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University
Adrenocortical Carcinoma
S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery
RATIONALE: Some tumors need growth factors produced by the body to keep growing. Suramin may interfere with the growth factor and stop the tumor from growing.
- Trial name
- NCT00002921
- Testing
- suramin, therapeutic hydrocortisone
- Where
- 65 sites in United States
- Volunteers
- 13 people
- Sponsor
- SWOG Cancer Research Network
Cushings Syndrome
Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature.
- Trial name
- NCT02646553
- Testing
- Children refered to the obesity clinic
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Mild Autonomous Cortisol Secretion (MACS)
Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)
This study will compare the efficacy and safety of the two 11β-hydroxylase inhibitors-metyrapone and osilodrostat-in patients with MACS.
- Trial name
- MOMACS (NCT07268222)
- Testing
- Metyrapone 250 mg Oral Tablets, Osilodrostat 1 MG, adrenalectomy
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Laikο General Hospital, Athens
Sports Physical Therapy
Comparative Effects of Tai Chi vs Full Body Vibrator Among Athletic Players
The aim of this study is to find out the Comparative effects of Tai chi and dynamic stretching exercises in reducing stress and insomnia among ameature athletics player's.
- Trial name
- NCT06696937
- Testing
- Tai chi, full body vibrator
- Where
- 2 sites in Pakistan
- Volunteers
- 43 people
- Sponsor
- Riphah International University
Stress, Signs and Symptoms, Digestive
The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
This study investigated the acute effect of the consumption of four different kinds of coffee (hot and cold instant coffee, cold espresso and hot filter coffee) with the same caffeine content on salivary gastrin, cortisol and…
- Conditions
- Stress, Signs and Symptoms, Digestive, Blood Pressure, Increased Secretion of Gastrin
- Trial name
- NCT02253628
- Testing
- Cold espresso, Hot instant coffee, Cold instant coffee
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Sleep, Morning Alertness
Investigating the Effects of Dairy Phospholipids on Sleep and Daytime Function in Healthy Adults.
The aim of the study is to investigate the effects of 6- and 12- week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on sleep and daytime function parameters in healthy adults.
- Conditions
- Sleep, Morning Alertness, Evening Alertness, Diurnal Cortisol
- Trial name
- NCT06663865
- Testing
- Active
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northumbria University
School Readiness, Developmental Delays
Early Intervention Foster Care: A Prevention Trial
The Early Intervention Foster Care [EIFC] project is an efficacy trial of the Oregon Social Learning Center Multidimensional Treatment Foster Care Program, a preventive intervention that targets 3 commonly co-occurring variables…
- Trial name
- EIFC (NCT00701194)
- Testing
- Early Intervention Foster Care (EIFC)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Oregon Social Learning Center
Cocaine Use Disorder
Impact of Cocaine Use and Withdrawal on Sleep
This study investigates how cocaine use and withdrawal affect sleep and circadian rhythms in individuals undergoing inpatient detoxification.
- Trial name
- CokeSo (NCT07119567)
- Testing
- Multimodal Sleep and Biomarker Assessment
- Where
- 3 sites in France
- Volunteers
- 32 people
- Sponsor
- Hôpital le Vinatier
Lymphoma, Non-Hodgkin
Autologous Followed by Non-myeloablative Allogeneic Transplantation for Non-Hodgkin's Lymphoma
The purpose of this trial is to develop an alternative treatment for patients with poor risk non-Hodgkin's lymphoma. This trial uses a combination of high dose chemotherapy with stem cell transplant using the patient's own cells.
- Trial name
- NCT00481832
- Testing
- Cyclophosphamide, BCNU, Etoposide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Critical Illness, Corona Virus Infection
Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19
The cytokine storms mediated by over production of proinflammatory cytokines have been observed in a large population of critically ill patients infected with COVID-19.
- Conditions
- Critical Illness, Corona Virus Infection, Cytokine Release Syndrome
- Trial name
- NCT04486521
- Testing
- Interleukin 6 (IL6) Antagonist, Interleukin 6 (IL6) Antagonist and corticosteroids, corticosteroid alone
- Where
- Saudi Arabia
- Volunteers
- 860 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Anorexia Nervosa, Hypothalamic Amenorrhea
Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea
The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.
- Conditions
- Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
- Trial name
- NCT00556036
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Motivation
Motivational Interviewing Inadequate Milk and Cortisol
Motivational interviewing is a technique used in many fields. No study has been found in national and international databases investigating the effect of motivational interviewing on the perception of insufficient milk…
- Trial name
- NCT06344663
- Testing
- motivational interview
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cystitis, Interstitial
DMSO Efficacy in IC/PBS Patients During and After Treatment
The purpose of this study is to examine the efficacy of dimethylsulphoxide (DMSO) cocktail in patients with interstitial cystitis during the treatment period (12 weeks) and after it (at 6 weeks, 3, 6 and 12 month).
- Trial name
- NCT01074567
- Testing
- DMSO cocktail
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Sepsis, Myopathy Critical Illness
Characterization and Longitudinal Monitoring of Muscular Phenotype in Patients Admitted to Intensive Care for Sepsis
Approximately 40% of patients develop muscle dysfunction during their stay in intensive care, particularly in the context of sepsis.
- Trial name
- REAMUS (NCT07074028)
- Testing
- Medical Research Council sum score (MRC-SS) test, Handgrip test combined with surface electromyography (sEMG), Electrical activity during maximal voluntary contraction of the rectus femoris
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier de Saint-Brieuc
Major Depression
Mineralocorticoid Receptor in the Treatment of Severe Depression
The proposed research aims to compare the onset of action and the efficacy of fludrocortisone, a mineralocorticoid receptor agonist vs. spironolactone, a mineralocorticoid antagonist, vs.
- Trial name
- NCT00295347
- Testing
- Spironolactone, fludrocortisone, escitalopram
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Mixed Lineage Acute Leukemia, Acute Myeloid Leukemia
Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies
This study will test the safety and effectiveness of adding bortezomib and vorinostat to other chemotherapy drugs commonly used to treat relapsed or refractory leukemia.
- Conditions
- Mixed Lineage Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoid Leukemia
- Trial name
- NCT02419755
- Testing
- Bortezomib, Vorinostat, Mitoxantrone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- St. Jude Children's Research Hospital
Hemophagocytic Lymphohistiocytosis
Hybrid Immunotherapy for Hemophagocytic LymphoHistiocytosis
Despite good progress during the last decade, hemophagocytic lymphohistiocytosis (HLH) remains difficult to treat. Two different treatment regimens have been used successfully.
- Trial name
- NCT01104025
- Testing
- ATG, rabbit, Etoposide, Methotrexate
- Where
- 15 sites in United States, Canada
- Volunteers
- 31 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Community-acquired Pneumonia, Influenza, COVID-19
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients…
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
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