Clinical trials: Hydrocortisone, completed
Congenital Adrenal Hyperplasia
A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH
Subjects completing study DIUR-005 and those who have already completed study DIUR-003 will be offered the opportunity either to continue Chronocort® therapy or to switch from their current glucocorticoid therapy to Chronocort®…
- Trial name
- NCT03062280
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Neurocrine UK Limited
Implant Therapy
Assessment of Deproteinized Bovine Bone for Immediate Implants Placement in Maxillary Esthetic Zone.
: Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Trial name
- Mohamed sedky (NCT07569146)
- Testing
- Immediate dental implants with bone graft augmentation (deproteinized bovine bone), Immediate dental implants without bone augmentation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Systemic Lupus Erythematosis
Circulating MicroRNAs in Understanding Pathogenesis of Systemic Lupus Erythematosis
This study aims to identify the expression signature of miR-181a, miR-196a and miR-21 in plasma of SLE patients and difference in their expression among groups with different systemic lupus erythematosis disease activity index…
- Trial name
- NCT02756546
- Testing
- Cyclophosphamide, Hydroxychloroquine, Hydrocortisone
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patient Admitted in Reanimation
Hydrocortisone Use After Etomidate in Intensive Care
the objective of the study is to assess the value of substitution with 200mg/24h of hydrocortisone for 48 hours for patients in intensive care who have received a single injection of etomidate
- Trial name
- NCT00862381
- Testing
- Hydrocortisone
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Grenoble
Nursing Caries, Newborn Illness
The Effect of Swaddling Method on Stress Level in Newborns Administration to Nasal CPAP
Transient tachypnea of newborn (TTN) causes 42.5%-60% of non-infectious respiratory distress cases in newborns, it is seen in only 1% of all newborns.
- Conditions
- Nursing Caries, Newborn Illness, Nurse's Role
- Trial name
- NCT05657977
- Testing
- nonpharmacologic intervention (swaddling)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Type 1 Diabetes, Stress
The Influence of Psychobiological Adversity to Children and Adolescents With Type 1 Diabetes
The aims of this study are two fold: To show whether there is an increased environmental or genetic susceptibility to stress in patients with T1D and whether it influences diabetes management.
- Trial name
- NCT02575001
- Testing
- Psychological background determinations, Genetic susceptibility determination, Cortisol release test
- Where
- Slovenia
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Case Selection and Treatment Protocol for Immediate Dental Implants in the Esthetic Zone
In this study a tooth that needs to be extracted will be replaced by an implant (artificial root) placed at the same appointment as the extraction.
- Trial name
- NCT02154581
- Testing
- SLActive implant
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Atopic Dermatitis, Psoriasis
Clinical, Psychological and Genetic Characteristics in Dermatological Patients
Atopic dermatitis (AD) and psoriasis (PS) are chronic, relapsing dermatological disorders with a high rate of psychiatric co-morbid pathology represented with depression.
- Trial name
- NCT03831646
- Where
- Kazakhstan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
Stress, Job, Student Burnout
Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students
The goal of this clinical trial is to evaluate stress biomarkers, subjective stress levels, and cognitive function in medical students.
- Conditions
- Stress, Job, Student Burnout, Stress, Physiological, Stress, Psychological
- Trial name
- NCT06125574
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Stress, Physiological, Stress, Psychological
Wise Interventions and Responses to Stress
This study compares the effects of two wise interventions (implicit theory of personality intervention and implicit theory of personality intervention plus self-affirmation) with a control condition in the stress responses of…
- Conditions
- Stress, Physiological, Stress, Psychological, Social Stress, Depression
- Trial name
- ITP-RSA (NCT04786496)
- Testing
- ITP+SA Wise intervention, ITP Wise intervention, Control condition
- Where
- Spain
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Traumatic Brain Injury, Trauma
Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Traumatic brained injured (TBI) patients frequently suffered from glucocorticoid insufficiency that is associated with a raise in the rate of pneumonia.
- Conditions
- Traumatic Brain Injury, Trauma, Adrenal Insufficiency, Pneumonia
- Trial name
- Corti-TC (NCT01093261)
- Testing
- Hydrocortisone Fludrocortisone
- Where
- 18 sites in France
- Volunteers
- 336 people
- Sponsor
- Nantes University Hospital
Covid-19, Hypoxia
Hydrocortisone for COVID-19 and Severe Hypoxia
We aim to assess the benefits and harms of low-dose hydrocortisone in patients with COVID-19 and severe hypoxia.
- Trial name
- COVID STEROID (NCT04348305)
- Testing
- Hydrocortisone, Sodium Chloride 9mg/mL
- Where
- 14 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Scandinavian Critical Care Trials Group
Physiological Stress, Psychological Stress
Descriptive Study of Biological Stress and Perceived Stress at the Center 15
The purpose of this study is to describe biological stress (cortisolemia) and perceived stress in Emergency Call Center Operators and Doctors while processing a center 15 call.
- Trial name
- RegulStress (NCT02075424)
- Testing
- salivary sampling by a biomnis swab
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Alcohol Use Disorder
Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation
This study proposes to examine both the peripheral and central nervous system responses when light social drinkers and binge/heavy social drinkers are exposed to visual ethanol cues, followed by oral ethanol.
- Trial name
- NCT04412824
- Testing
- Intravenous blood draw
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Auburn University
Type 1 Diabetes
Glucose Variability in Type 1 Diabetes and Its Effect on Factors That Influence New Vessel Formation
The aim of the study is to see how glycaemic control and glycaemic variability affect levels of HIF, VEGF, erythropoietin and cortisol in Paediatric Type 1 diabetics on insulin pump therapy.
- Trial name
- INDIGO 2 (NCT01429467)
- Testing
- Continuous Glucose Monitor (CGM) and Telemedicine (Enlite Guardian real-time system Medtronic®)
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Dundee
Atopic Dermatitis
A Study of Lebrikizumab in Participants With Persistent Moderate to Severe Atopic Dermatitis
This randomized, double-blind, placebo-controlled study will evaluate the safety and efficacy of lebrikizumab administered subcutaneously (SC) in adult participants with persistent moderate to severe atopic dermatitis (AD) who…
- Trial name
- NCT02340234
- Testing
- Lebrikizumab, TCS Cream
- Where
- 74 sites in United States, Australia and 12 more
- Volunteers
- 212 people
- Sponsor
- Hoffmann-La Roche
Cushing's Disease
Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease
This is a randomized, double-blind, multicenter, phase III study to evaluate the safety and efficacy of 2 dosing regiments of Pasireotide long acting release (LAR) in patients with Cushing's disease.
- Trial name
- NCT01374906
- Testing
- pasireotide LAR, SOM230 LAR 30 mg, SOM230 LAR 10 mg
- Where
- 82 sites in United States, Argentina and 18 more
- Volunteers
- 150 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer, Painful Neuropathy
The Effect of an Inter-Disciplinary Program, Including MBSR, in Breast Cancer Survivors With Chronic Neuropathic Pain
Chronic neuropathic pain is a common problem for breast cancer survivors. Even with the best medical treatment, some survivors continue to experience disabling pain.
- Conditions
- Breast Cancer, Painful Neuropathy, Chronic Pain, Worries; Pain or Disability
- Trial name
- InDepth (NCT02125006)
- Testing
- Mindfulness-Based Stress Reduction
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- Ottawa Hospital Research Institute
Cannabis Use Disorder
Cannabinoids and Biological Reactivity to Stress
The goal of this study is to test the impact of two drugs that produce temporary stress-like symptoms, both in isolation and together, on cannabis use motivation in individuals with Cannabis Use Disorder.
- Trial name
- COBRAS (NCT06430580)
- Testing
- Hydrocortisone Oral, Yohimbine Hydrochloride
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Florida State University
Early Interventions, Preterm Infants
Effects of Early Behavioral and Transaction Interventions on Preterm Infants' and Parents' Biopsychosocial Well-being
This randomized controlled trial will use a longitudinal repeated-measures design to examine the effects of two interventions, behavioral support interventions and a parent-infant transactional program, on parents' stress, PPD…
- Conditions
- Early Interventions, Preterm Infants, Parent-Child Relations
- Trial name
- NCT03013023
- Testing
- BS, Routine care, PITP
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan