Clinical trials: Hydrocortisone, completed
Pregnancy, Gestational Diabetes Mellitus
Predictability of Gestational Diabetes Mellitus in First and Second Trimester
The objective of the study is, if an early oral glucose tolerance test combined with maternal history, condition and multiple biomarker analysis can be used to detect gestational diabetes mellitus in the first trimester (12-14…
- Trial name
- GDMPredict (NCT02035059)
- Where
- Switzerland
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tympanic Membrane Perforation
Fibrin Monomer Compared With Hemostatic Sponge in the Integrity of the Graft During Tympanoplasty
The diagnosis of tympanic perforation reaches a high number of records in otorhinolaryngology services worldwide. Most of the tympanoplasties are performed in patients whose cause of perforation and hearing loss was chronic…
- Trial name
- TISSUCOL (NCT02120651)
- Testing
- Fibrin monomer, Hemostatic sponge
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CLOTILDE FUENTES OROZCO
Mucormycosis; Pulmonary (Etiology)
Amphotericin Versus Posaconazole for Pulmonary Mucormycosis
Pulmonary mucormycosis is a serious illness with high morbidity and mortality (approximately 57%). Surgery and antifungal therapy are central in the management of mucormycosis.
- Trial name
- NCT05468372
- Testing
- Posaconazole 600 mg followed by posaconazole 300 mg once daily, Liposomal Amphotericin B
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Stress, Anhedonia
Brain Mechanisms of Emotion and Motivation: A Mind-Body Study
The purpose of this research study is to investigate how the brain processes emotions, and the way these processes affect behavior.
- Conditions
- Stress, Anhedonia, Healthy
- Trial name
- MIDAS (NCT01850472)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder
Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder
Approximately, post-traumatic stress disorder (PTSD) occurs in 8% of the adult population over time. Exposure to traumatic events increases the risk of poor physical health and often leads to disability.
- Trial name
- NCT00815204
- Testing
- MRI of the pituitary, DEX/CRH test
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Hypercortisolism
A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas
This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal adenoma or hyperplasia associated with…
- Trial name
- GRADIENT (NCT04308590)
- Testing
- Relacorilant
- Where
- 45 sites in United States, Austria and 7 more
- Volunteers
- 137 people
- Sponsor
- Corcept Therapeutics
Hospitalized Child
Effect of Augmented Reality Books on Cortisol Levels in Hospitalized Pediatric Patients
Hospitalization is a stressful event that might impact in a patient's recovery. Children are more susceptible to suffer acute stress as a result of a hospital stay.
- Trial name
- NCT03537859
- Testing
- Augmented Reality, Non Augmented Reality
- Where
- Peru
- Volunteers
- 29 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Opiate
Effects of Diacetylmorphine (DAM) on Brain Function and Stress Response
The aims of the study are to investigate the effects of diacetylmorphin (heroin) on brain using functional magnetic resonance imaging (fMRI), coupled with measurements of cortisol concentrations and neurophysiological stress…
- Trial name
- NCT01174927
- Testing
- diacetylmorphine (DAM)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Stress Oxidative
Effect of Baseline Cortisol Level on Lipid Peroxidation Products in Young Female Swimmers
Research group: twenty-four and homogeneous female swimmers, who train swimming intensively and attend the Sports Championship School Complex.
- Trial name
- NCT06895616
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Poznan University of Physical Education
Genital Neoplasms, Female, Insomnia
Cognitive Behavioral Effects on Sleep, Pain, and Cytokines in Gynecologic Cancer
Gynecologic cancers cause substantial morbidity and mortality among women. Developing, implementing, and disseminating interventions that reduce morbidity and mortality secondary to gynecologic cancers are a public health…
- Conditions
- Genital Neoplasms, Female, Insomnia, Pain, Adaptation, Psychological
- Trial name
- NCT02609880
- Testing
- Cognitive Behavioral Therapy, Psychoeducation
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Florida
Asthma
A Phase I Study in Asthma Patients Evaluating the Effect of Doses of FlutiForm™ on the Amount, if Any, of Cortisol Produced by the Adrenal Glands
The medications being used in this study are individually approved by the Food and Drug Administration (FDA). The medication under investigation is a combination of the two medications in one inhaler.
- Trial name
- NCT00657774
- Testing
- FlutiForm 250/10 ug, FlutiForm 100/10 ug, Oral Prednisone 10mg
- Where
- 19 sites in United States
- Volunteers
- 160 people
- Sponsor
- SkyePharma AG
Polycystic Ovary Syndrome
Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome
Hypothesis The overall hypothesis is that non-obese (BMI <30) women with PCOS have high luteinising hormone (LH) and cortisol pulse frequency and amplitude and that repeated low-frequency EA restore these alterations and induce…
- Trial name
- PCOSLFEA (NCT00921492)
- Testing
- Low-frequency electro-acupuncture (EA), Meeting a therapist - attention control
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Göteborg University
Heroin Dependence, Learning and Memory
Effect of Stress on Heroin-Related Memory Retrieval
The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.
- Trial name
- NCT00759005
- Testing
- propranolol and cortisol
- Where
- China
- Sponsor
- National Institute on Drug Dependence, China
Breastfeeding
Effect of Early Skin to Skin Contact on Breast Feeding Behaviour in Term Newborns: A Randomized Controlled Trial
Aims and Objectives Aim To determine the effect of delivery room Skin To Skin contact on breast feeding behavior of term neonates born by normal vaginal delivery at 36-48 hours.
- Trial name
- NCT00776789
- Testing
- skin to skin contact, Control group
- Where
- India
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
21-hydroxylase Deficiency
Examining Genetic Differences Among People With 21-Hydroxylase Deficiency
Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the amount of steroids that the body forms. The most common form of CAH is 21-hydroxylase deficiency (21OHD), which leads to cortisol deficiency.
- Trial name
- NCT00542841
- Testing
- Hydrocortisone withdrawal
- Where
- 3 sites in United States, Brazil
- Volunteers
- 99 people
- Sponsor
- Maria I. New
Diabetes Mellitus Type 2
Comparison of Progressive Muscle Relaxation and Stretching Exercises in Diabetic Population
The goal of this clinical trial is to compare the effects of Progressive muscle relaxation and stretching exercises mediated by stress on heart rate variability, cortisol level, galvanic skin response and perceived stress scale.
- Trial name
- NCT06780878
- Testing
- Progressive muscle relaxation technique, Stretching exercises, Control Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
- Trial name
- NCT06275490
- Testing
- Partially Demineralized Dentin Block, L-PRF block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Critical Illness
Cortisol Levels as a Measure of Accumulated Physiological Stress in ICU Patients Undergoing Mechanical Ventilation
Critical illness is a situation of severe and prolonged stress for patients with mechanical ventilation (MV). Between 40-80% of these patients present the Post-ICU syndrome, a set of physical, cognitive, psychological alterations…
- Trial name
- Corti-COG (NCT03736135)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Corporacion Parc Tauli
Autonomic Disturbances in Parkinson's Disease
Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson's Disease -Treatment
Disabling symptoms of blood pressure dysregulation, impaired swallowing and digestion are common amongst Parkinson's patients. So far the exact pathophysiology for this is not fully understood.
- Trial name
- NCT01993680
- Testing
- Pyridostigmine bromide, fludrocortisone
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Christian Baumann