Clinical trials: Hydrocortisone, completed
Phobia
Cortisol in the Treatment of Phobias
The aim of this prospective, double-blind, placebo-controlled, randomized study is to investigate if glucocorticoid treatment, in combination with exposure therapy, helps to reduce phobic fear in patients with phobia.
- Trial name
- NCT00451750
- Testing
- Cortisol
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Acute Hepatitis
ADRENAL FUNCTION IN PATIENTS WITH ACUTE HEPATITIS
A high frequency of adrenal dysfunction (AD) has been reported in severe acute hepatitis (SAH) using the dosage of serum total cortisol (STC).
- Trial name
- CORT-HEPAT (NCT02859584)
- Testing
- Measure OF SERUM TOTAL CORTISOL, SERUM FREE AND SALIVARY CORTISOL
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Immediate Dental Implants
Accuracy of Selective Laser Sinteredcomputer Guided Stents Versus Digital Light Processing Stents
patient with non-restorable tooth in the esthetic zone will be recruited in the study. a traumatic is done and implant will be placed using either digital light processed guides for control group or selective laser sintering…
- Trial name
- RCT (NCT03287934)
- Testing
- selective laser sintered stent, digital light processing(dlp)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Immunologic Response to Negative Cognition in Persons With Chronic Pain
Principal Investigator/Program Director (Last, First, Middle): Darnall, Beth APS Future Leaders in Pain Small Research Grants Application Page 5 Continuation Format Page Summary: Chronic pain is stressful, both physically and…
- Trial name
- NCT00677911
- Testing
- In-vivo pain catastrophizing induction
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Oregon Health and Science University
Septic Shock
Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
The purpose of this study is to determine whether the combination therapy (vitamin C,thiamine and hydrocortisone) is effective in the treatment of septic shock.
- Trial name
- NCT03872011
- Testing
- Vitamin C,thiamine,hydrocortisone
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Northern Jiangsu People's Hospital
Hyperglycemia
Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock
The purpose of this study is to compare hyperglycemia and other effects, include 28-day mortality and time to reversal of shock between 100 milligrams and 200 milligrams of hydrocortisone as initial dosage in patients with septic…
- Trial name
- NCT02266264
- Testing
- Hydrocortisone
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Srinakharinwirot University
Acute Respiratory Distress Syndrome (ARDS), Multiple Organ Failure
Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) in combination with multi-organ dysfunction syndrome (MODS) is a life-threatening condition, particularly when treatment modalities such as extracorporeal membrane oxygenation (ECMO) and…
- Trial name
- IP steroid (NCT01423864)
- Testing
- conventional ECMO with intravenous steroid, solumedrol
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- National Taiwan University Hospital
Leukemia, Lymphocytic, Lymphoblastic Lymphoma
Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)
AINV18P1 is a Phase 1 study where palbociclib will be administrated in combination with a standard re-induction platform in pediatric relapsed Acute Lymphoblastic Leukemia (ALL) and lymphoblastic lymphoma (LL).
- Conditions
- Leukemia, Lymphocytic, Lymphoblastic Lymphoma, T-cell Lymphoma, T-cell Leukemia
- Trial name
- NCT03792256
- Testing
- Palbociclib, Cytarabine, Methotrexate
- Where
- 19 sites in United States
- Volunteers
- 12 people
- Sponsor
- Children's Oncology Group
Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma
Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer
This randomized phase I/II trial studies gemcitabine hydrochloride and vismodegib to see how well they work compared with gemcitabine hydrochloride alone in treating patients with recurrent or metastatic pancreatic cancer.
- Conditions
- Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma, Stage IV Pancreatic Cancer AJCC v6 and v7
- Trial name
- NCT01064622
- Testing
- Gemcitabine Hydrochloride, Vismodegib
- Where
- 25 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Cancer Institute (NCI)
Major Depressive Disorder, Anxiety Disorders
Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration
The current study will test the causal relationship between elevated levels of cortisol and the serotonin transporter gene (5-HTTLPR) as these factors influence sensitivity to environmental threat.
- Trial name
- 5-HTTLPR (NCT01710202)
- Testing
- Hydrocortisone
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Neuroendocrine Reproductive Status
Impacts of Metabolic Variation on Neuroendocrine Control of Reproduction
This study will evaluate the potential effects of a changing metabolic environment on GnRH hypothalamic neurons, by performing studies of LH pulsatility (basal and during clamp studies) in different groups of male subjects fed…
- Trial name
- NCT01058681
- Testing
- effect of metabolic variations on LH pulsatility
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Post Operative Pain, Erector Spinae Plane Block
The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response
Laparoscopic cholecystectomy is one of the most common operations in abdominal surgery. Effective analgesia in the postoperative period; It is of great importance in terms of acceleration of recovery, prevention of atelectasis…
- Conditions
- Post Operative Pain, Erector Spinae Plane Block, Inguinal Hernia
- Trial name
- NCT05717530
- Testing
- wound site local anesthesic infiltration, Erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Implant Tissue Failure
One-abutment One-time for Immediate Restoration Procedure in the Esthetic Zone
Objectives: The aim of this randomized control trial was to compare immediate restoration procedure with a one abutment one-time technique using a conventional versus full digital workflow.
- Trial name
- IONE (NCT04139512)
- Testing
- guided surgery, conventionnel implant placement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Liege
Pain
The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair
The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine for interscalene brachial plexus blocks for elective shoulder surgery would enhance the duration and effect of analgesia when…
- Trial name
- NCT02766556
- Testing
- dexmedetomidine, ISB, Ropivacaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Food Addiction, How Opioid Tone Was Related to Self Reported
Stress, Hormones, and Eating
The investigators will develop a measure of endogenous opioid tone that might serve as a biological marker for drive for palatable food.
- Conditions
- Food Addiction, How Opioid Tone Was Related to Self Reported, Drive to Eat Using a Measure of Food Addiction
- Trial name
- SHE (NCT01175512)
- Testing
- Naltrexone
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Single Effort in Air Temperature of Minus 10°C
Exercise in the cold is an attractive option for many athletes. Erythrocyte aggregation, as one of the main rheological parameters, constitutes an important indicator of microcirculation and oxygen transport capacity in the human…
- Trial name
- NCT07664072
- Testing
- cold, neutral
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Implant Therapy, Class II Extraction Sockets
Customized CAD/CAM Titanium-Milled Abutments Vs. Custom Abutments Over Immediate Implants in Class II Extraction Sockets in the Esthetic Zone: a Randomized Controlled Clinical Trial
Background: Immediate implant placement in esthetic zones, particularly Class II and III extraction sockets, presents challenges related to soft and hard tissue changes post-extraction.
- Trial name
- NCT06791655
- Testing
- Stock Abutment Implant, Customized CAD CAM Titanium Milled Abutment Implant
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Prostate Cancer
Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy and androgen suppression may kill more tumor cells.
- Trial name
- NCT00002855
- Testing
- Bicalutamide, Doxorubicin hydrochloride, Estramustine Phosphate Sodium
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- M.D. Anderson Cancer Center
Stress, Burnout, Professional
Using Yogic Breathing to Reduce Stress in Anesthesia Personnel As Measured by Hair Cortisol
Mind body exercises have long been used as a way for individuals to reduce stress and improve well-being. Recent studies indicate that yogic breathing (YB, also known as pranayama) could potentially impact both the mind and body…
- Trial name
- NCT04858815
- Testing
- yogic breathing
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina