Clinical trials: Ibuprofen, completed
Patent Ductus Arteriosus
IV Acetaminophen and Patent Ductus Arteriosus
This is a randomized controlled trial to evaluate the efficacy of IV acetaminophen versus IV ibuprofen in closing a hemodynamically significant patent ductus arteriosus in preterm infants.
- Trial name
- NCT03008876
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Post-operative Pain
Prospective Pain Study Comparing Different Treatments After Hand Surgery
The purpose of the study is to evaluate the efficacy of three different types of pain medication (Oxycodone - an opioid, Ibuprofen - a non-steroidal anti-inflammatory, and Acetaminophen - a non-opioid analgesic) in the management…
- Trial name
- NCT03597308
- Testing
- 5mg of Oxycodone every 6 hours as needed for pain, 600mg of Ibuprofen every 6 hours as needed for pain, 500mg of Acetaminophen every 6 hours as needed for pain
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Rothman Institute Orthopaedics
Glaucoma, Ocular Hypertension
Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
The Purpose of This Study is to Determine if Taking an Over the Counter Non-Steroidal Anti-Inflammatory(Ibuprofen)has an Effect on Eye Pressure in Patients using Brimonidine(Alphagan)and Latanoprost(Xalatan) eye drops.
- Trial name
- NCT00402493
- Testing
- ibuprofen, latanoprost, brimonidine, Ibuprofen, brimonidine, latanoprost, Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 51 people
- Sponsor
- Philadelphia Eye Associates
Ankle Sprains
Approach to Ankle Sprains in the Emergency Department
The aim of this study is to evaluate the short-term effects of routinely applied agents on pain and joint range of motion (ROM) in ankle sprains presenting to the emergency department (ED).
- Trial name
- NCT06563271
- Testing
- Dexketoprofen Trometamol 50 Mg/mL Solution for Injection, Ibuprofen 100 MG/ML Solution for Injection, Paracetamol 10 Mg/mL Solution for Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Lung Diseases
Rhomboid Intercostal Block for Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Analgesia management is very important for these patients in postoperative period since insufficient…
- Trial name
- NCT04428216
- Testing
- Group RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Pain
Topical Ibuprofen for Delayed Onset Mulscle Soreness
The objective of this study is to compare the efficacy and safety of Ibuprofen 5% Topical Gel versus placebo administered two or three times daily for the treatment of pain associated with delayed onset muscle soreness following…
- Trial name
- NCT01794923
- Testing
- IBU BID, IBU TID
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Pfizer
Tonsil Disease, Pain Management
Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy Cases
This study aims to evaluate the efficacy and safety of intranasal Diclofenac Sodium, intranasal Ibuprofen, and intranasal Paracetamol for pain control following tonsillectomy in pediatric patients.
- Conditions
- Tonsil Disease, Pain Management, Intranasal Drug Administration
- Trial name
- NCT06731556
- Testing
- Intravenous paracetamol, Intranasal Paracetamol, Intranasal Diclofenac Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Low Back Pain
Acupuncture in Acute Nonspecific Low Back Pain
Acute low back pain is a common disorder in general practice. Some general practitioners (GPs) treat acute low back pain (LBP) with acupuncture, despite lacking evidence of its effectiveness for this condition.
- Trial name
- Acuback (NCT01439412)
- Testing
- Acupuncture and standard treatment, Standard treatment in general practice
- Where
- Norway
- Volunteers
- 185 people
- Sponsor
- University of Oslo
Moderate or Severe Submental Fullness
Patient Experience Study of Deoxycholic Acid Injection
The objectives of this study are to determine the safety of deoxycholic acid subcutaneous (SC) injections in the submental area and to evaluate the effects of four interventions, relative to placebo in the submental area…
- Trial name
- NCT02007434
- Testing
- Deoxycholic Acid Injection, Cold Compress, Lidocaine / Epinephrine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Kythera Biopharmaceuticals
Pain
Paracetamol / Ibuprofen for Postpartum Pain in the Early Postpartum Period
The investigators will examine the effectiveness of non-opioid analgesia (Paracetamol versus Ibuprofen) in the early postpartum period
- Trial name
- NCT04653506
- Testing
- Paracetamol 1000 mg, Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Post Endodontic Pain
Comparative Evaluation of Transdermal and Oral Drugs for Management of Post-Endodontic Pain
This clinical trial evaluated whether two drugs delivered through transdermal drug delivery systems reduced post-endodontic pain as effectively as two orally administered medications in adult patients undergoing root canal…
- Trial name
- PATCH-PAIN (NCT07610265)
- Testing
- Ketoprofen transdermal patch, Fentanyl transdermal patch, Diclofenac sodium tablet
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Nims University Rajasthan
Pneumonia
Effectiveness Study of Integrative Treatment for Pediatric Pneumonia
The purpose of this study is to evaluate the effectiveness of traditional Chinese medicine for treatment of pediatric pneumonia. It is a multicenter randomized controlled trial.
- Trial name
- NCT02069665
- Testing
- Fuxiong San, Xiyanping injection, Ribavirin Injection
- Where
- 6 sites in China
- Volunteers
- 451 people
- Sponsor
- Liaoning University of Traditional Chinese Medicine
Primary Dysmenorrhea
Moxibustion for Primary Dysmenorrhea
Hypothesis: Moxibustion is effective for managing primary dysmenorrhea. Aim: To attest the effectiveness and safety of moxibustion for primary dysmenorrhea. Design: A randomized controlled trial.
- Trial name
- NCT01972906
- Testing
- moxibustion, Ibuprofen Sustained Release Capsules
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Pain
Ibuprofen Versus Acetaminophen vs Their Combination in the Relief of Musculoskeletal Pain in the Emergency Setting
The purpose of this study is to determine whether the combination of ibuprofen and acetaminophen, is more effective than either single agent alone in treating pain from acute musculoskeletal injuries in the emergency department.
- Trial name
- NCT01827475
- Testing
- Ibuprofen, Acetaminophen, Ibuprofen-acetaminophen combination
- Volunteers
- 90 people
- Sponsor
- Stony Brook University
Osteoarthritis, Knee
Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)
The purpose of the study is to see if generic ibuprofen has an effect on osteoarthritis knee pain during a series of timed walks on a treadmill.
- Trial name
- NCT00565084
- Testing
- ibuprofen
- Volunteers
- 33 people
- Sponsor
- Merck Sharp & Dohme LLC
Sarcopenia, Osteoporosis
Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training
The purpose of this study is to determine if taking the pain reliever acetaminophen (ACET) interferes with some of the benefits of weight lifting on muscles and bone density in older men.
- Conditions
- Sarcopenia, Osteoporosis, Aging
- Trial name
- NCT01083901
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoarthritis
The Efficacy and Safety of Curcuma Domestica Extracts and Ibuprofen in Knee Osteoarthritis
Osteoarthritis of knee is common degenerative musculoskeletal diseases. Non-steroidal antiinflammatory drugs (NSAIDs) are used to decrease pain symptom but someone can not tolerate its gastrointestinal adverse effects.
- Trial name
- NCT00792818
- Testing
- Curcuma domestica extracts, Ibuprofen
- Where
- 6 sites in Thailand
- Volunteers
- 367 people
- Sponsor
- Mahidol University
Pain
A Study To Evaluate Methods To Evaluate Back Pain
The study is designed to assess methods used in clinical research.
- Trial name
- NCT01045993
- Testing
- Heat Device, marketed analgesic
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Malignant Pleural Effusion, Pleural Effusion
The First Therapeutic Intervention in Malignant Pleural Effusion Trial
Fluid caused by cancer cells may accumulate in the lining of the lung. Draining the fluid with a chest tube may relieve pain and shortness of breath.
- Trial name
- TIME-1 (NCT00896285)
- Testing
- Large bore chest drain + NSAID based analgesic regimen, Small bore chest drain + NSAID based analgesic regimen, Large bore chest drain + opiate based analgesic regimen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Davis
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University