Clinical trials: Ibuprofen, completed
Pain
Comparative Efficacy of 4 Oral Analgesics
The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.
- Trial name
- NCT02455518
- Testing
- Oxycodone/acetaminophen, Hydrocodone/acetaminophen, Codeine/acetaminophen
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Montefiore Medical Center
Physiological Effect of Drugs, Morphine
Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for…
- Conditions
- Physiological Effect of Drugs, Morphine, Analgesics, Analgesics, Opioid
- Trial name
- NCT04369950
- Testing
- 2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes Mellitus, Type 1
DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen
The objectives of this study is to evaluate the safety and influence of treatment with GAD-Alum (Diamyd) combined with Vitamin D and Ibuprofen on preservation of residual insulin secretion in recently diagnosed Type 1 Diabetes…
- Trial name
- NCT01785108
- Testing
- GAD-Alum (Diamyd) 20 µg, GAD-Alum (Diamyd) 20 µg X 2, Vitamin D
- Where
- 10 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Johnny Ludvigsson
Osteoarthritis, Controlled Hypertension
Safety and Efficacy of Lumiracoxib in Patients With Osteoarthritis and With Controlled Hypertension
This study will investigate the effect on ambulatory blood pressure of lumiracoxib 100 mg once daily versus ibuprofen 600 mg three times a day in osteoarthritis patients with controlled hypertension.
- Trial name
- NCT00267176
- Testing
- lumiracoxib
- Where
- 2 sites in United States, Germany
- Volunteers
- 1,020 people
- Sponsor
- Novartis Pharmaceuticals
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Fractures
The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in children with fractures or those who have surgery to correct bony deformity requiring the bone to be cut…
- Trial name
- NCT02076321
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Missouri-Columbia
Pain, Postoperative
Study of Pain Control in Diagnostic Hysteroscopy
The goal of this clinical trial study is to learn about how to decrease the pain during the diagnostic hysteroscopy. The main question it aims to answer is "Do the Paracetamol and Ibuprofen taken before the procedure can lower…
- Trial name
- NCT06188143
- Testing
- Ibuprofen-Paracetamol
- Where
- Thailand
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Osteoarthritis, Knee
Ibuprofen Gel or Capsaicin Cream for my Painful Knee Osteoarthritis?
Despite evidence that topical non-steroidal anti-inflammatory drugs (NSAIDs) and capsaicin are effective in osteoarthritis (OA), it is still unclear why they work for some people but not others.
- Trial name
- NCT03146689
- Testing
- Topical NSAID, Topical Capsaicin
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Nottingham
Tooth, Impacted, Trismus
Efficacy of Chronoterapy in Oral Surgery
Lower third molar extraction is one of the most common treatments in oral surgery practice. It is a treatment with inherent complications such as postoperative pain, swelling or trismus.
- Conditions
- Tooth, Impacted, Trismus, Pain, Inflammatory Response
- Trial name
- ECOS (NCT05126264)
- Testing
- Ibuprofen 400 mg
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Cervicobrachial Neuralgia
Hypoalgesic Effect of Neural Mobilization Versus Ibuprofen Pharmacologic Treatment
The purpose of this study is to compare the effectivity of Median Nerve Neural Mobilization and oral Ibuprofen in treating patients who suffer cervicobrachial pain
- Trial name
- NCT02593721
- Testing
- Median Nerve Neural Mobilization, Ibuprofen
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Universidad Europea de Madrid
Postoperative Pain
PK and Safety After C-Section
The main goal of the study was to measure the amount of the active ingredients and other components of HTX-011 in plasma and expressed breast milk over time following postpartum administration in women undergoing a planned…
- Trial name
- NCT03955211
- Testing
- HTX-011, ZYNRELEF kit components for administration, MMA regimen
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Heron Therapeutics
Chronic Low Back Pain
A Double Blind Placebo Study to Determine the Effectiveness of Theramine on the Management of Chronic Back Pain
This research protocol will compare Theramine to a non-steroidal anti-inflammatory drug (NSAID) in the treatment of chronic back pain.
- Trial name
- NCT01490905
- Testing
- Theramine (A medical food), Theraprofen, Ibuprofen
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Targeted Medical Pharma
Pain, Thyroidectomy
Non-opioid Based Pain Control After Thyroidectomy
Pain control modalities were evaluated after thyroidectomy.
- Trial name
- NCT03988075
- Testing
- Acetaminophen and hydrocodone based pain control, Acetaminophen and ibuprofen based pain control
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medstar Health Research Institute
Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
Feasibility Study to Evaluate a New Energy Storage and Return Prosthetic Foot
A prospective, interventional, multicenter pilot study to characterize differences in performance and patient reported outcomes between the Taleo, Proflex XC, and the new Revo prosthetic foot.
- Conditions
- Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Knee
- Trial name
- NCT04239222
- Testing
- Revo-M, Taleo, Proflex XC
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Postoperative Pain, Narcotic Use
Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery
The study is a randomized controlled trial investigating a multimodal postoperative pain management protocol which will include use of ice therapy and scheduled opioid-sparing medications for pain control after minimally invasive…
- Conditions
- Postoperative Pain, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT04710277
- Testing
- Opioid-sparing multimodal pain management, Usual care
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Abortion in First Trimester
Nitrous Oxide for Pain Management of First Trimester Surgical Abortion
The purpose of this research is to study the effect of nitrous oxide on pain felt by women having a surgical termination at less than 11 weeks compared to pain felt by women receiving oral pain medications.
- Trial name
- NAB (NCT02096575)
- Testing
- Nitrous oxide administration
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Gynecologic Surgery
A Fast-track Versus Conventional Recovery Protocol in Laparoscopic Hysterctomy
Factors affecting to length of hospital stay after fast-track recovery program in laparoscopic hysterectomy compared to conventional recovery program
- Trial name
- NCT03828981
- Testing
- fast-track recovery program
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Osteoarthritis
An Investigational Drug in Patients With Osteoarthritis (0663-073)
This study was conducted to assess the safety and tolerability of an investigational drug and to evaluate its effectiveness in the treatment of osteoarthritis of the hip or knee in both men and women.
- Trial name
- NCT00092755
- Testing
- MK0663, etoricoxib
- Volunteers
- 548 people
- Sponsor
- Organon and Co
Musculoskeletal Pain
Acetaminophen (APAP) +/- Oxycodone
This is an emergency department based randomized study of oxycodone/ acetaminophen versus acetaminophen alone for patients with acute musculoskeletal pain refractory to ibuprofen
- Trial name
- NCT04122443
- Testing
- Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Montefiore Medical Center
Bone Resorption, Stress Fracture
The Effects of NSAIDs on Bone Metabolism Following Exercise
The purpose of this study is to determine the effects of a single dose of non-steroidal anti-inflammatory drugs on post-exercise markers of bone and muscle metabolism.
- Conditions
- Bone Resorption, Stress Fracture, Bone Injury
- Trial name
- NCT05512013
- Testing
- Ibuprofen 800 mg, Celecoxib 200mg, Flurbiprofen 100 mg
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine