Clinical trials: Ibuprofen
Post Operative Pain, Impacted Third Molar Tooth
Pain Control Following Third Molar Surgery
In this study, the investigators recruited patients undergoing surgical removal of impacted third molar teeth. Participants will be randomly divided into two groups Group 1: The patient will receive 400mg of ibuprofen plus 1000mg…
- Trial name
- NCT06514222
- Testing
- Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given together every 8 hours, Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given alternatively every four hours
- Where
- United Arab Emirates
- Volunteers
- 56 people
- Sponsor
- University of Sharjah
Patent Ductus Arteriosus
Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates
Patent ductus arteriosus (PDA) is a common problem in preterm babies. Recently there have been various studies for and against an association between thrombocytopenia and PDA.
- Trial name
- NCT03022253
- Testing
- Liberal platelet transfusion, Restrictive platelet transfusion, Paracetamol
- Where
- India
- Volunteers
- 44 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Complication Due to Immunization
Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants
Background: Inflammation may depress respiration in neonates. The aim of this study was to establish a link between post-immunization inflammation and cardio-respiratory events (CRE).
- Trial name
- NCT02726178
- Testing
- Advil® Pediatric drops for infants
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Prematurity of Fetus, Patent Ductus Arteriosus
Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants
The purpose of this study is to examine the influence medical or surgical treatment for patent ductus arteriosus in preterm infants on cerebral and renal tissue oxygenation and on cardiac output.
- Trial name
- NCT01428180
- Testing
- Indomethacin, Surgical Ligation, Ibuprofen
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University of Ulm
Upper Extremity Fractures, Analgesia Post Fracture
Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24…
- Trial name
- NCT01690780
- Testing
- Oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Naveen Poonai
Postoperative Pain, Third Molar
Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient.
- Conditions
- Postoperative Pain, Third Molar, Postoperative Complications
- Trial name
- NCT03398382
- Testing
- Magnesium tablet group, Magnesium lozenge group
- Where
- 2 sites in Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniel Jerković
Acute Pain
OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department
Patients 18 to 65 years old who present within 72 hours of onset pain will be considered for study enrollment. Patients with the acute musculoskeletal low back or neck pain based on ED history and structural physical exam will be…
- Trial name
- NCT06987578
- Testing
- OMT vs. Ibruprofen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- St. Joseph's Regional Medical Center, New Jersey
Radiation Cystitis
Efficacy of Low-Intensity Shockwave Therapy in Treating Radiation Cystitis
Radiation-induced cystitis is a condition commonly seen in patients who have undergone radiation therapy, especially those treated in the pelvic region.
- Trial name
- NCT07016451
- Testing
- Li-ESWT, Medication
- Where
- Thailand
- Volunteers
- 25 people
- Sponsor
- Thanakrit Visuthikosol
Shoulder Syndrome
Ultrasound-Guided Erector Spinae Plane Block or Interscalen Brachial Plexus Block Following Arthroscopic Shoulder Surgery
Postoperative pain is important following arthroscopic shoulder surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.Ultrasound (US)-guided brachial plexus blocks such as…
- Trial name
- NCT04083287
- Testing
- Erector spinae plane block (Group E), Interscalen brachial plexus block (Group I)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Irreversible Pulpitis With Apical Periodontitis
Effect of Common Analgesia on Pulp Sensibility
his study will investigate whether commonly used analgesics - 400 mg ibuprofen and 500 mg paracetamol - influence the accuracy of pulpal sensibility tests (cold test and electric pulp test) in patients with symptomatic…
- Trial name
- NCT07125911
- Testing
- Ibuprofen 400 mg (if necessary), Paracetamol 500 mg
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- HITEC-Institute of Medical Sciences
Gonarthrosis; Primary
The Effect of Different Intra-articular Injections Primary Gonarthrosis
Gonarthrosis is a frequent cause of knee pain and mostly related to altered function of the knee. Intra-articular injections are a valuable noninvasive medical treatment of choice for pain management and functional enhancement.
- Trial name
- NCT05291793
- Testing
- Tenoxicam 20 Mg Powder for Solution for Injection Vial, Methylprednisolone, Saline
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nevsehir Haci Bektas Veli University
Alzheimer's Disease
Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease
This is a global Phase III, randomized, double-blinded, placebo-controlled study for subjects with evidence of early AD. The protocol is designed to determine whether ALZT-OP1 combination treatment (ALZT-OP1a + ALZT-OP1b) will…
- Trial name
- COGNITE (NCT02547818)
- Testing
- ALZT-OP1a, ALZT-OP1b
- Where
- 121 sites in United States, Australia and 5 more
- Volunteers
- 620 people
- Sponsor
- AZTherapies, Inc.
IUD Removal
Use of Ibuprofen to Prevent IUD Site Effects
This research will determine whether prophylactic use of ibuprofen can prevent common side effects of the copper intrauterine device (IUD) and prevent early removal of the device.
- Trial name
- NCT00243815
- Testing
- ibuprofen
- Where
- Chile
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- FHI 360
Forearm Injuries, Pain, Acute
Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
Children presenting to the Emergency Room with the chief complaint of forearm injury and/or pain will be randomized to receive oral Oxycodone or Ibuprofen to control pain.
- Conditions
- Forearm Injuries, Pain, Acute, Pediatric ALL
- Trial name
- NCT04523623
- Testing
- Oxycodone, Ibuprofen
- Sponsor
- Washington University School of Medicine
Pain, Postoperative
Study of MK-0663/Etoricoxib in Postorthopedic Knee Replacement Surgery Pain (MK-0663-098)
The purpose of this study was to evaluate the efficacy and safety of Etoricoxib compared to placebo and ibuprofen in the treatment of postoperative pain associated with unilateral total knee replacement surgery.
- Trial name
- NCT00820027
- Testing
- Etoricoxib 90 mg, Etoricoxib 120 mg, Ibuprofen 600 mg
- Volunteers
- 776 people
- Sponsor
- Organon and Co
Lung Diseases
Erector Spinae Plane Block or Serratus Anterior Plane (SAP) Block Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960762
- Testing
- ESP block (Group ESP), SAP block (Group SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
NSAID Related Gastric Irritation
Pilot Study of OXP001 and Brufen in Healthy Subjects
Oxford Pharmascience (the sponsor) is developing a new formulation of Ibuprofen (OXP001 - the study drug) which it is proposed will have less of the side effects than are currently reported with standard prescription strength…
- Trial name
- NCT02050958
- Testing
- OXP001, Ibuprofen
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Oxford Pharmascience Ltd
Osteoarthritis, Knee, Osteoarthritis, Hip
Helping Osteoarthritis Patients to Walk With NSAID
There is a lack of effective analgesic treatments to help walking patients with painful hip/knee osteoarthritis. Our team therefore imagined a new strategy lying on a multimodal rehabilitation walking program with the help of a…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Pain
- Trial name
- PERIPATEI (NCT05761015)
- Testing
- therapeutic program including intermittent drug intake and multimodal rehabilitation program
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Clermont-Ferrand
Contraception
The Effect of Ibuprofen on Intrauterine Contraceptive Device Associated Uterine Bleeding
The Copper intrauterine device is the most common method of reversible contraception worldwide. Abnormal uterine bleeding and pain are the most common medical indications for the discontinuation of the intrauterine device.
- Trial name
- NCT02580344
- Testing
- Ibuprofen
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Assiut University
Healthy
Bioequivalence Study of Dr.Reddy's Ibuprofen and Diphenhydramine Citrate 200 mg/38 mg Caplets Under Fasting Condition
To determine the single-dose oral bioequivalence study of Ibuprofen and Diphenhydramine citrate 200 mg/38 mg caplets of Dr. Reddy's Laboratories Limited, India and Advil® PM, of Wyeth consumer health care, USA, in normal…
- Trial name
- NCT01053208
- Testing
- Ibuprofen and Diphenhydramine Citrate
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited