Clinical trials: Intervention Group
Demyelinating Diseases of the Central Nervous System, Child
Core Stability, Functional Capacity, Balance, Strength, and Fatigue in Pediatric Demyelinating Diseases
This study aims to evaluate balance ability, core stability, functional capacity, lower extremity muscle strength, and fatigue levels in children diagnosed with central nervous system demyelinating diseases, in order to…
- Conditions
- Demyelinating Diseases of the Central Nervous System, Child, Core Stability, Balance
- Trial name
- PEDI-CORE (NCT07654738)
- Testing
- No ADT
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain
The Role of Opioidergic Systems in Breathing Based Analgesia
The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing induced pain relief is mediated by endogenous opioids in response to intravenous (IV) administration of the opioid antagonist naloxone…
- Trial name
- NCT03419858
- Testing
- Mindfulness Meditation, Slow-Breathing, Naloxone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Chemotherapy-induced Neuropathy
Home-Based Exercise and Vagus Nerve Stimulation for Chemotherapy-Induced Neuropathy
Background: Studies highlight the potential benefits of home-based exercise for cancer survivors with chemotherapy-induced neuropathy (CIN); however, its effectiveness in alleviating CIN-related sensorimotor impairments and…
- Trial name
- CIN (NCT07877558)
- Testing
- Active non-invasive vagus nerve stimulation (nVNS), Home-based aerobic and resistance exercise program
- Where
- 3 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Ankylosing Spondylitis
Wet Cupping Therapy in Ankylosing Spondylitis
This study evaluates the efficacy of wet cupping therapy in patients with ankylosing spondylitis.Wet cupping therapy will be applied to half of the patients plus routine pharmaceutical treatment while the other half will receive…
- Trial name
- NCT05792358
- Testing
- wet cupping therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Karabuk University
PTSD
Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD
The purpose of this study is to test an intensive, multi-couple group version of a couple therapy for PTSD delivered to active duty Service Members or Veterans with PTSD and their romantic partners in a single weekend retreat.
- Trial name
- NCT03158558
- Testing
- Accelerated, Multi-Couple Group CBCT for PTSD
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Penn State University
Sexual Dysfunction
Motivational Interviews With Women Experiencing Sexual Dysfunction During Menopause Period
The aim of this study is to evaluate the effect of motivational interviews with women who experience sexual dysfunction during menopause on sexual quality of life and self-efficacy.The population of the study consisted of…
- Trial name
- NCT06337058
- Testing
- Experimental group (motivational interview)
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hülya KAMALAK
Schizophrenia, Schizoaffective Disorder
Shared Decision Making for Antipsychotic Medications
This study aims to provide an evidence-based shared decision making intervention for antipsychotic medications, the Antipsychotic Medication Decision Aid (APM-DA), for individuals experiencing early psychosis and provide, for the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Delusional Disorder
- Trial name
- NCT05416658
- Testing
- The Antipsychotic Medication Decision Aid (APM-DA)
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Hidradenitis Suppurativa (HS)
Acceptability of MBSR for People With HS
Hidradenitis suppurativa (HS) is a chronic inflammatory condition that causes painful, recurring abscesses and nodules. It is associated with psychological stress and impaired quality of life.
- Trial name
- NCT07903948
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Francisco
Systemic Sclerosis
Utility of Breath-holding Test in Systemic Sclerosis
This study aims to evaluate the utility of breath-holding test as a marker of pulmonary disease severity in patients with systemic sclerosis.
- Trial name
- NCT04484948
- Testing
- scleroderma health assessment questionnaire (SHAQ), BHT, and 6MWT
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Low Back Pain
Pilot Study on Digitally Supported Home Exercises for the Management of Unspecific Low Back Pain.
The overall purpose of the study is to investigate effect of Digitally Supported Home Exercises (DSHE) in different groups for which digitally supported interventions could be beneficial.
- Trial name
- NCT04364243
- Testing
- Digitally supported home exercises
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Patent Ductus Arteriosus in Preterm Infants
Noninvasive Hemodynamics Assessment of Preterms With Successful Medical Closure of PDA
The aim of our study was to use Electrical Cardiometry EC to monitor hemodynamic alternations during pharmacological closure of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm neonates
- Trial name
- NCT06606015
- Testing
- I.V Paracetamol., Echocardiography., Electrical Cardiometry
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Tanta University
Coronary Artery Disease
Assessment of Stent Malapposition and Neointimal Coverage on Optical coHerence Tomography at Post-procedure and 3 Months After Platinum Chromium Alloy Of the Element™ Stent Implantation
The purpose of this study is to compare the degree of stent malapposition on an immediate optical coherence tomography (OCT) after nominal stent pressure and at a final post-procedure OCT (ANCHOR-I) and the neointimal coverage on…
- Trial name
- ANCHOR (NCT01581515)
- Testing
- Promus Element everolimus eluting coronary stent, Xience Prime everolimus eluting coronary stent
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Tonsil Hypertrophy
Effect of the Combination of Dexamethasone and BIS Monitoring on Reducing Postoperative Nausea and Vomiting in Children
This study will investigate the impact of combining dexamethasone and bispectral index (BIS) monitoring on the incidence of postoperative nausea and vomiting, emergence delirium and recovery trajectories in children undergoing…
- Trial name
- BISDEX (NCT07299435)
- Testing
- BIS monitoring
- Where
- 5 sites in Czechia
- Volunteers
- 1,508 people
- Sponsor
- University Hospital Ostrava
Chronic Disease
Multimorbidity Management Supported by a Digital Platform
This study aims to assess whether the use of the METHIS digital platform using a patient-centered approach contributes to an improvement in the quality of life, mental health and physical activity of patients with multimorbidity…
- Trial name
- NCT05593835
- Testing
- METHIS Platform, Goal-Oriented Care Training Program
- Volunteers
- 1,380 people
- Sponsor
- Universidade Nova de Lisboa
Atopic Dermatitis (Eczema)
Assessment of cfDNA-STING Axis as a Potential Pathological Marker in Atopic Dermatitis
Study Overview Atopic dermatitis (AD), commonly known as eczema, is a chronic inflammatory skin condition characterized by intense itching and skin barrier damage.
- Trial name
- NCT07573735
- Testing
- blood sampling
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Intrabony Periodontal Defect
Comparison Between Bioactive Silica Graft Plus Platelet Rich Fibrin and Only Platelet Rich Fibrin Graft in Intrabony Defects With Diabetes
Various regenerative procedures used for the treatment of intabony defects.The Aim of this study is to compare the treatment outcome of bioactive silica graft with platelet rich fibrin Vs bioactive silica graft in the treatment…
- Trial name
- CBBSGPPOPIDWD (NCT03651908)
- Testing
- Conventional Flap Surgery
- Where
- India
- Volunteers
- 14 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Hearing Loss
Randomised Study of Web-Based Auditory Training With Varying Perceptual and Cognitive Demands on Training Gains and Generalised Speech, Cognitive, and Communication Outcomes
WP1: PLUS-Auditory Training The goal of this experimental study is to better understand how task difficulty affects on-task learning thresholds and generalised benefits in two PLUS auditory training tasks involving perceptual and…
- Trial name
- PLUS-Optimal (NCT07506408)
- Testing
- Practice Listening and Understand Speech (PLUS)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sleep, Physical Activity
Effects of a Wearable Device and Social Media-Based Intervention on Physical Activity and Sleep Quality in Adults
The goal of this randomized controlled trial is to examine whether the use of a wearable device and social media based intention increases physical activity and enhance sleep quality among adults.
- Trial name
- NCT06739876
- Testing
- Wearable device-based intervention (with motivational support via social media), Wearable device-based intervention (without support)
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Class II Extraction Socket, Defected Buccal Bone
Enhancement of Deficient Labial Bone Using Bone Ring Technique and Tent Pole Technique With Immediate Implant Placement
Introduction: Replacing single rooted teeth with immediate implant is quit challenging in the anterior region where the buccal bone is usually deficient, moreover the bone loss increases with the extraction of tooth and the…
- Trial name
- NCT07171476
- Testing
- Guided bone regeneration, bone ring technique, Tent pole technique
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Suez Canal University
Lymphomas, B-cell Lymphomas
A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas
To find the highest tolerable dose of JV-213 (a type of autologous CAR T cell therapy) that can be given to patients who have B-cell lymphoma that is relapsed or refractory.
- Trial name
- NCT05773040
- Testing
- JV-213, Leukapheresis
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
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