Clinical trials: Intervention Group
Perinatal Depression, PostPartum Depression
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression
There is considerable evidence that most perinatal women at risk for postpartum depression do not engage in mental health services, even when referred by home visiting (HV) programs, primary care physicians, obstetricians, or…
- Trial name
- NCT02979444
- Testing
- Mothers and Babies Groups
- Where
- United States
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hypovitaminosis D
The Effect of Hypovitaminosis D and Vitamin D Supplementation on Fracture Nonunion Rates
The purpose of the study is to determine whether vitamin D supplementation in patients with hypovitaminosis D can decrease nonunion (failure to heal) incidence in patients with fractures of the humerus, femur, or tibia.
- Trial name
- VitD (NCT01691833)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Wake Forest University Health Sciences
Couples
TYRO Couples Project Study
This study uses an RCT design with repeated measures to test the impact of two different delivery formats for the TYRO Couples curriculum.
- Trial name
- NCT05267236
- Testing
- Intervention #1: Treatment Group Receiving On-Demand TYRO Services, Intervention #2: Control Group Receiving In-Person TYRO Services
- Where
- United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Midwest Evaluation & Research
Diabetes
Intervention to Promote Weight Loss in Latinas At-risk for Diabetes
The overarching goal of this project is to develop and test a behavioral intervention delivered by promotoras to help at-risk Latinas lose weight and prevent diabetes.
- Trial name
- NCT02088034
- Testing
- Promotora-led Intervention, Metformin Therapy, Usual Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Temple University
Acute Coronary Syndrome
Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I
The purpose of this randomized, multi-site, clinical trial is to determine whether intensive therapy consisting of cholesterol-lowering statin drugs plus apheresis to cleanse the blood of low-density lipoprotein (LDL) cholesterol…
- Trial name
- PREMIER (NCT01004406)
- Testing
- intensive LDL-lowering therapy, standard statin monotherapy
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Chondromalacia Patella, Patellofemoral Pain Syndrome
Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia
The purpose of this study is to determine how safe a knee injection called Synvisc-One® is in patients with a condition called chondromalacia patella and how well in works in treating the condition.
- Trial name
- NCT01771952
- Testing
- Synvisc-One™
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Virginia
Premature Birth
Group Antenatal Care: Effectiveness and Contextual Factors Linked to Implementation Success in Malawi
In this study, we test the effectiveness of an evidence-based model of group antenatal care by comparing it to individual (usual) antenatal care (Aim 1) across 7 antenatal clinics in Blantyre District, Malawi.
- Trial name
- NCT03673709
- Testing
- Antenatal Care
- Where
- 7 sites in Malawi
- Volunteers
- 1,887 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Lymphocyte Depletion
Lymphocyte Depletion and Change in Lymphocyte Functionality
Lymphocytes are a type of white blood cell (WBC) responsible for adaptive immunity. Thoracic tumors are adjacent to many blood/immune rich organs including the great vessels, heart, thoracic-spine, and lymph-node-stations.
- Trial name
- NCT04273893
- Testing
- SBRT with additional treatment planning dose optimization, SBRT with standard of care planning only, Blood Draws
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Virginia
type1diabetes
Feasibility Trial of a Mindfulness Based Intervention in Youth With Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic illnesses of childhood. The involved treatment regimen, including daily insulin administration/pump management, frequent blood glucose checks, and careful track-ing of food…
- Trial name
- BREATHE-T1D (NCT05268393)
- Testing
- BREATHE-T1D
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
COVID-19 Testing Behaviors
Examining How a Text Message-based Educational Intervention Influences COVID-19 Testing
In this Phase III study, the investigators will build off of the Phase II embedded study with some adjustments to the design to address new research priorities that examine an intervention that is network informed and delivered…
- Trial name
- NCT07074171
- Testing
- Text message-based education intervention, Historical Control
- Where
- 3 sites in United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity
A Toolbox Approach to Obesity Treatment in Primary Care
Obesity is common, causing many medical problems in adults (e.g., diabetes, hypertension, high cholesterol, sleep apnea, heart attack, strokes). A range of treatments have shown to be effective for treating obesity.
- Trial name
- Toolbox (NCT01922934)
- Testing
- Commercial weight loss program, Colorado Weigh, Meal replacements
- Where
- United States
- Volunteers
- 4,730 people
- Sponsor
- Denver Health and Hospital Authority
Wound Healing
Evaluating the Efficacy and Safety of the VERAFLO™ Dressing Kit for Wound Bed Preparation in Open Wounds
The objectives are to evaluate the efficacy and safety of the V.A.C. VERAFLO™ Dressing Kit for wound bed preparation in open wounds with extensive soft tissue damage in this trial.
- Trial name
- NCT05902793
- Testing
- Investigational device: V.A.C. VERAFLO™ Dressing Kit, Comparator device: Negative pressure wound drainage material
- Where
- 4 sites in China
- Volunteers
- 170 people
- Sponsor
- KCI USA, Inc
Patient Care Team
The Learning Outcome of Resuscitation Teamwork Training in Postgraduate Year Doctors and Nurses
It is challenging for healthcare team to manage emergency patient effectively. Most of these critical patients have medical conditions and need complex medical managements.
- Trial name
- NCT05302414
- Testing
- Board game-based learning, Simulation-based learning, Lecture-based learning
- Where
- Taiwan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Aging
Aerobic Exercise and Cerebrovascular Function
This proposal will evaluate two brain health measures, cerebrovascular perfusion and cerebrovascular reactivity (CVR), before and after a proven, interval-based, aerobic exercise intervention in older Veterans.
- Trial name
- NCT03803904
- Testing
- Spin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Type 2
Water Up@ At Home: An Intervention to Replace Sugary Drinks With Water
This study will test the preliminary effects of an intervention to reduce sugary drinks among low-income parents (n=38)(primary caregivers) and their young children (6 months-3 year olds) compared to a control group (n=38).
- Trial name
- NCT05159622
- Testing
- Water Up! at Home
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- George Washington University
Overweight and Obesity
Randomized Trial Of Achieving Healthy Lifestyles In Psych Rehabilitation
This study will determine whether a behavioral weight loss intervention including dietary counseling and exercise is effective in helping people with serious mental illnesses lose weight.
- Trial name
- ACHIEVE (NCT00902694)
- Testing
- ACHIEVE Intervention, Control
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- Johns Hopkins University
Pain Control, Ureteral Reimplantation
ITM vs QL for Pediatric Open Lower Abdominal Procedures
Patients between the ages of 12 months and 11 years who are undergoing an open lower abdominal procedure will be randomized to receive intrathecal morphine, or bilateral quadratus lumborum block.
- Conditions
- Pain Control, Ureteral Reimplantation, Pediatrics, Intrathecal Morphine
- Trial name
- NCT05506930
- Testing
- Intrathecal Morphine, Quadratus lumborum block
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Medical University of South Carolina
Hepatitis A, Hepatitis B
Antibody Persistence & Immune Memory in Healthy Adults Previously Vaccinated With Twinrix Adult
This study will evaluate the persistence of the immune response to HAV (Hepatitis A Virus) antigens and HBs (Hepatitis B surface) antigens in healthy adults previously vaccinated with GlaxoSmithKline (GSK) Biologicals' Twinrix…
- Trial name
- NCT01000324
- Testing
- Blood sampling, Engerix-B, Havrix
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Pain
Pilot Testing of a Behavioral Intervention for Chronic Pain in Individuals With HIV
Due to its specific pathophysiology and impact on health outcomes, the Institute of Medicine has described chronic pain as a complex chronic disease and a "national public health crisis." The unique neurobiological basis and…
- Trial name
- NCT02824562
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Pittsburgh
Parenting, Breastfeeding
Evaluating a Coparenting Breastfeeding Support Intervention
The purpose of this trial is to evaluate the effectiveness of a Coparenting Breastfeeding Support Intervention with first time parents on exclusive breastfeeding rates at 12 weeks postpartum.
- Trial name
- COSI (NCT01536119)
- Testing
- Coparenting Breastfeeding Support Intervention
- Where
- Canada
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- University of Toronto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.