Clinical trials: Intervention Group
Leukemia, Lymphoma
Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL)
The goal of this clinical research study is to learn if intense management and control of blood sugar levels during treatment for acute lymphocytic leukemia, Burkitts lymphoma, or lymphoblastic lymphoma will result in decreased…
- Trial name
- NCT00500240
- Testing
- Insulin Glargine, Insulin Aspart
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- M.D. Anderson Cancer Center
Dystonia, Parkinson Disease
Lesioning Procedures for Movement Disorders
Dystonia is a rare syndrome with varying etiologies. Similarly, tremor conditions refractory to medical management and disabling that they need surgical interventions are rare in our setting.
- Conditions
- Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT06352268
- Testing
- Pallidal, subthalamic or thalamic lesioning
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences
Coronary Heart Disease, Heart Failure
Efficacy of Physical Exercise in Cardiac Rehabilitation
Physical rehabilitation is a key element in the treatment of patients with cardiovascular diseases, and recent evidence has shown that supervised exercise programmes can prevent cardiovascular events, improve physical function…
- Conditions
- Coronary Heart Disease, Heart Failure, Ischemic Heart Diseases
- Trial name
- NCT01617850
- Testing
- Supervised physical exercise training x3 weekly for 12 weeks, Supervised physical exercise training x2 weekly for 8 weeks
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital Skejby
Flip Learning, Education
Flipped Learning in Physiotherapy Education
This study will evaluate the effectiveness of flipped learning in an undergraduate physiotherapy and rehabilitation course on urogenital and maternal health.
- Conditions
- Flip Learning, Education, Physiotherapy and Rehabilitation
- Trial name
- NCT07707050
- Testing
- Flipped Learning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Patient Outcomes
Program in Oncology for Tribal Health Systems.
This clinical trial aims to develop and implement more navigation assistance programs tailored specifically for Native American cancer patients, addressing the current lack of available support.
- Trial name
- NCT07217574
- Testing
- C3PO
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Oklahoma
Massive Rotator Cuff Tears
Arthroscopic Treatment of Massive Rotator Cuff Tears With Debridement and Biodegradable Spacer.
Massive rotator cuff tears are common in the adult population. It is estimated that about 12 % of adults 60 years of age or older suffer from a rotator cuff injury.
- Trial name
- AMRIS (NCT04571918)
- Testing
- Biodegradable spacer, Debridement and biceps tenotomy
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Bladder Urothelial Carcinoma, Bladder Cancer
Safety Analysis and Oncological Outcomes in HoLERT vs TURBT
Bladder urothelial cancer is the second most common urologic tumor and represents a worldwide public health problem. Most cases are diagnosed as non-muscle invasive tumors, and can be treated with transurethral resection of…
- Trial name
- NCT05833997
- Testing
- Monopolar Transurethral resection of bladder tumor, Holmium Laser resection of bladder tumor (HoLEBT)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Aortic Valve Disease
Health Status of Patients After Surgically Implanted Biological and TAVI: a Population-based Retrospective Analysis
The overall project aim is to study outcomes following aortic valve replacement with surgically implanted bioprostheses or TAVI by retrieving data from the main social security carriers in Austria for the years 2010-2020.
- Trial name
- NCT05912660
- Testing
- Aortic Valve Replacement
- Volunteers
- 18,882 people
- Sponsor
- Medical University of Vienna
Atherosclerosis, Ischemia
Clinical Study of Stent Versus Direct Atherectomy to Treat Lower Limb Ischemia
This is a randomized study comparing stent and plaque excision systems in treatment of lower limb (superficial femoral or popliteal artery) ischemia.
- Trial name
- NCT02514460
- Testing
- plaque excision system, Stent
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Thyroid Carcinoma
Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib
This is a non-interventional, multi center post-authorization safety study that includes all patients diagnosed as Unresectable Differentiated Thyroid Carcinoma (DTC) and treated with Sorafenib within a certain period.
- Trial name
- JPMS-DTC (NCT02185560)
- Testing
- Sorafenib (Nexavar, BAY43-9006)
- Where
- Japan
- Volunteers
- 453 people
- Sponsor
- Bayer
Older People
Impact of a Musical Intervention in Older Adults (ARA Project - Armonía Recreativa Para El Adulto Mayor)
Currently, the world is facing the challenge of population aging. At this stage of life, various deteriorations, such as cognitive decline, begin to appear, significantly impairing the quality of life.
- Trial name
- ARA (NCT06787820)
- Testing
- Music intervention
- Where
- Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Alkaptonuria
Suitability of Nitisinone in Alkaptonuria 2
This is a proposal to develop the orphan designated drug, nitisinone, for the treatment of a rare Mendelian disease, Alkaptonuria (AKU).
- Trial name
- SONIA 2 (NCT01916382)
- Testing
- Nitisinone
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- University of Liverpool
Type 2 Diabetes
GLucobay M OBservation Study for Efficacy and Safety in Treatment of Type-2 Diabetes Patients
An observational and multicenter study to assess the effectiveness and safety of Glucobay®- M under daily life treatment of type-2 diabetes patients.The study objectives are to investigate the effectiveness and safety of…
- Trial name
- GLOBE (NCT01219582)
- Testing
- Glucobay M (Acarbose/Metformin, BAY81-9783)
- Where
- India
- Volunteers
- 9,364 people
- Sponsor
- Bayer
Esophageal Cancer
Cola Ingestion for Esophageal Bolus Impaction
The aim of the study is to observe whether cola ingestion can improve the 24-hour remission rate of acute esophageal impaction in patients with esophageal cancer.
- Trial name
- NCT06652620
- Testing
- Cola
- Where
- 5 sites in China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Abdominal Surgery, General Anesthesia
Effect of Reflective Blanket on Undesirable Perioperative Hypothermia
The aim of this study is to determine the effect of using reflective blankets, which is a passive insulation product, on preventing UPH in patients scheduled for abdominal surgery under general anesthesia.
- Conditions
- Abdominal Surgery, General Anesthesia, General Surgery
- Trial name
- NCT05702320
- Testing
- the heating procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Öğr. Gör. Ali GÜZEL
Lung Cancer, Nonsmall Cell, COPD
Breathe Easier II: A Dyad-based Multiple Behavior Intervention
This pilot randomized control trial (RCT) will test a 12-week, multiple behavior intervention physical activity and stress management for survivors with early stage lung cancer (stages I-III) and their family members (1 survivor…
- Conditions
- Lung Cancer, Nonsmall Cell, COPD, Self-Management, Physical Inactivity
- Trial name
- BE (NCT05956782)
- Testing
- Breathe Easier
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Critically Ill, Acute Kidney Injury
Non-interventional Follow-up Versus Fluid Bolus in RESPONSE to Oliguria in the Critically Ill
Background: After hypotension, oliguria (urine output less than 0.5 mL/kg/h) was the most common trigger to administer fluid bolus in a multinational practice survey in intensive care.
- Conditions
- Critically Ill, Acute Kidney Injury, Sepsis, Oliguria
- Trial name
- RESPONSE (NCT02860572)
- Testing
- follow-up without intervention, fluid bolus
- Where
- 2 sites in Finland
- Volunteers
- 130 people
- Sponsor
- Helsinki University Central Hospital
Rheumatoid Arthritis, Inflammatory Arthritis
Sleep and Exercise in Rheumatoid Arthritis
Regular physical activity is important for people with rheumatoid arthritis (RA). Sleep requirements for adults should be on a 'sleep needs spectrum' of between 7 to 9 hours per day.
- Trial name
- NCT03140995
- Testing
- Walking Programme
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of Limerick
Sarcopenia
Multicomponent Training and Muscle Quality in Older Women
This study aims to evlauate the effect os a 32-week multicomponent training (MT) program on muscle architecture and muscle quality (assessed by ultrasound) in womer over 60 years.
- Trial name
- NCT07359495
- Testing
- Multicomponent training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
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