Clinical trials: Intervention Group, completed
Middle Cerebral Artery Aneurysm
Risk Factors of Middle Cerebral Artery Aneurysm.
According to the current view, cerebral aneurysms are acquired degenerative lesions resulting from hemodynamic stress. This single-center case-control study will be carried out at the Department of Neurosurgery, Regional Hospital…
- Trial name
- MCAA (NCT03493035)
- Testing
- Computed tomography angiography (3D CTA), Transcranial color-coded sonography (TCCS)
- Where
- Poland
- Volunteers
- 190 people
- Sponsor
- Medical University of Silesia
Type2 Diabetes Mellitus, Hyperglycemia
Heart Rate During Exercise in Type 2 Diabetes
Exercise training is a cornerstone for the prevention and treatment of metabolic disorders and associated cardiometabolic complications such as type 2 diabetes mellitus (T2D) and hypertension.
- Conditions
- Type2 Diabetes Mellitus, Hyperglycemia, Heart Rate, Exercise Training
- Trial name
- HRinT2DM (NCT03917576)
- Testing
- Behavioral, Exercise training intervention
- Where
- Chile
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad de Los Lagos
Elderly, Older Adults
The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial
The PAINFREE (Improving PAIN control following FRactures; towards an Elder-friendly Emergency department) Initiative is a patient-centered multifaceted intervention which aims to improve pain management in patients 75 years and…
- Conditions
- Elderly, Older Adults, Bone Fracture, Emergency Department
- Trial name
- PAINFREE (NCT03082417)
- Testing
- Implementation
- Where
- Canada
- Volunteers
- 1,375 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Health Communication
Information Visualizations to Facilitate HIV-related Patient-provider Communication in New York City (Info Viz: HIV-NYC)
To complete the study aims, a mixed methods study that includes a single group pretest-posttest study design will be used to pilot test the infographic intervention.
- Trial name
- NCT04102540
- Testing
- Infographic intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Diabetes Mellitus, Hyperglycemia
Durban Diabetes Study:A Study of the Epidemiology of Diabetes Mellitus in Urban South Africans of African Descent (DDS)
Type 2 diabetes (T2D) is an emerging epidemic in sub-Saharan Africa, with an estimated prevalence of 6%. With around seven million cases of T2D in 2000, it is anticipated that over 18 million Africans will have the disease by…
- Conditions
- Diabetes Mellitus, Hyperglycemia, Hereditary Diseases, Glucose Intolerance
- Trial name
- DDS (NCT02416440)
- Testing
- blood sample
- Where
- South Africa
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis)
Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults
Multicenter, phase III, randomized, blinded, controlled, parallel group with safety extension phase with crossover or continued treatment.
- Trial name
- ENLIGHTEN 1 (NCT05219968)
- Testing
- LYR-210, Background Therapy
- Where
- 55 sites in United States, Austria and 3 more
- Volunteers
- 196 people
- Sponsor
- Lyra Therapeutics
Heart Diseases
A Partnership to Translate an Evidence-based Intervention (Take Heart) for Vulnerable Older Adults With Heart Disease
To evaluate the effectiveness of Take Heart, a behavioral/educational program for adults age 50+ with heart disease, or with at least two risk factors for heart disease, that helps them to better manage their health condition(s).
- Trial name
- NCT02950818
- Testing
- Take Heart
- Where
- United States
- Volunteers
- 453 people
- Sponsor
- University of Michigan
Gross Motor Development Delay, Social Skills
SKIPping With PAX: An Integrated Gross Motor and Social-Emotional Skill Intervention
The purpose of this study was to test the effects of an integrated intervention on the gross motor and social-emotional development of rural preschool boys and girls.
- Conditions
- Gross Motor Development Delay, Social Skills, Social Behavior, Sedentary Behavior
- Trial name
- NCT04656990
- Testing
- Integrated Intervention
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Palliative Care, Terminal Illness
'LIFEView' Audiovisual Technology: Virtual Travel to Support Wellbeing and Quality of Life at the End of Life
This study is looking to assess the use of an audio-video technology called 'LIFEView' using a laptop and large-screen TV. This tool intends to support life review or reminiscence of past experiences, escape from current…
- Conditions
- Palliative Care, Terminal Illness, Quality of Life, Psychological Distress
- Trial name
- NCT04030910
- Testing
- 'LIFEView'
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Bruyère Health Research Institute.
Rehabilitation, Spinal Fusion
Effect of a Case Manager to Assist the Rehabilitation for Lumbar Spinal Fusion Patients. A Randomised Controlled Trial.
The aim of the current study is to examine the effect of a case manager-assisting rehabilitation program compared to usual physical rehabilitation for patients undergoing a lumbar spinal fusion on functional disability, pain, and…
- Conditions
- Rehabilitation, Spinal Fusion, Case Managers
- Trial name
- NCT03433443
- Testing
- Case manager assisted rehabilitation, Usual physical rehabilitation
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnant Women, Pregnancies at Increased Risk of Preterm Birth
Comparison in Cervical Length and Prolongation of Gestation Age on Vaginal Progesterone Administration to Pregnant Women After the Acute Phase of Threatened Preterm Birth
This randomised clinical trial aims to investigate the effect of daily vaginal progesterone supplementation on pregnancy prolongation and cervical length changes following arrested preterm labor in singleton pregnancies.
- Trial name
- NCT06975943
- Testing
- Progesterone 200 mg vaginal capsules
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Dr. Soetomo General Hospital
Coronary Artery Disease, Coronary Stenosis
An Evaluation of a Physiology-guided PCI Optimisation Strategy
There has recently been renewed interest in the measurement of post percutaneous coronary intervention (PCI) Fractional Flow Reserve (FFR).
- Trial name
- Target-FFR (NCT03259815)
- Testing
- P.I.O.S., Pre and post-PCI coronary physiology measurements
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- NHS National Waiting Times Centre Board
Overweight and Obesity, Time Restricted Feeding
Fasting ENHANCE Pilot Study
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable…
- Conditions
- Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
- Trial name
- NCT05732935
- Testing
- Time Restricted Eating intervention, Successful Aging Comparison Group (LEARN)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Smoking Cessation
Evaluation of an Intensive Education Program on the Treatment of Tobacco Use Disorder for Pharmacists: a Randomized Controlled Trial
In Qatar, tobacco use is one of the main causes of premature deaths and preventable diseases. As per the 2013 Global Adult Tobacco Survey (GATS), 12.1% of adults and 20.2% of men in Qatar smoke tobacco, and 55.4% of this smoke an…
- Trial name
- NCT03518476
- Testing
- intensive multi-disciplinary education program on tobacco treatment for pharmacists, Control arm
- Where
- Qatar
- Volunteers
- 164 people
- Sponsor
- Qatar University
Spinal Cord Injury
SCIPA Full-On :Intensive Exercise Program After Spinal Cord Injury
The study is a multi-centre, assessor-blind, randomised controlled phase III trial in patients with with complete or incomplete spinal cord injury between C6 and T12.
- Trial name
- SCIPAFull-On (NCT01236976)
- Testing
- Therastride Treadmill System, FES-assisted cycling, Trunk and upper and lower limb exercises
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 116 people
- Sponsor
- University of Melbourne
Robot-Assisted Radical Prostatectomy
Effect of Control Ventilation, PEEP, and PEEP With ARM in Robot-assisted Radical Prostatectomy
The goal of this clinical trial is to determine whether different ventilatory strategies improve oxygenation and hemodynamic stability in patients undergoing robot-assisted radical prostatectomy under general anesthesia.
- Trial name
- NCT07462689
- Testing
- PEEP group, PEEP + ARM group
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ilsan Cha hospital
Gamification, Nutrition
Usability and Feasibility of the NutriQuest Application
The study is a pilot study (phase 2) that includes a usability study (phase 1). The aim of the study is to investigate the feasibility and usability of the healthy nutrition application and the effects on adherence to Modified…
- Conditions
- Gamification, Nutrition, Behavior Change
- Trial name
- NCT05884489
- Testing
- A gamified smartphone app-based eating behaviour intervention
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Post Traumatic Stress Disorder
The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD)
Oxytocin (OT) - a neurohormone and neuromodulator which is mainly synthesized in the hypothalamus - is a key mediator of complex social and affective behaviors, including emotional empathy.
- Trial name
- NCT01325168
- Testing
- syntocinon nasal spray
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Hip Fractures
The Stronger at Home Study
Hip fracture is a major health problem facing older adults. Hip fractures result in higher mortality, morbidity, and costs than all other osteoporotic fractures combined.
- Trial name
- NCT04228068
- Testing
- Rehabilitation Program, Pain self management, Conventional care
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Dr. Mohammad Auais, PhD
Stroke
Community Participation Transition After Stroke
Stroke is one of the most serious, disabling health conditions in the United States. Patients who undergo rehabilitation treatment for stroke have a high rate of disability.
- Trial name
- COMPASS (NCT02396589)
- Testing
- Education Group, Home Modifications Group
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
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