Clinical trials: Intervention Group, completed
At Risk Youth
Development and Evaluation of a Growth Mindset Intervention for Adolescents in Youth Custody Frameworks: Pilot Study
The purpose of this study is to develop and evaluate a daily-activity-based intervention aimed at fostering a growth mindset among adolescents in youth custody frameworks and their staff.
- Trial name
- NCT06824012
- Testing
- Growth Mindset Intervention
- Where
- Israel
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Miri Tal-Saban
Periapical Periodontitis, Root Canal Infection
Efficacy of Apical Preparation With Passive Ultrasonic Irrigation in Reducing Intracanal Bacteria
This study evaluates intracanal bacterial load in molar teeth with chronic apical periodontitis before and after root canal shaping with two different apical enlargement sizes and ultrasonic irrigation activation.
- Trial name
- NCT07005219
- Testing
- Root canal shaping with One Curve Mini #25/0.4 and passive ultrasonic irrigation, Root canal shaping with One Curve Mini #35/0.4 and passive ultrasonic irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hemorrhagic Shock, Traumatic Injury
Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial
Open label, multi-center, pre-hospital randomized trial utilizing 10 level-1 trauma centers designed to determine the efficacy and safety of low titer whole blood resuscitation as compared to standard of care resuscitation in…
- Trial name
- TOWAR (NCT04684719)
- Testing
- low titer whole blood, Standard Care
- Where
- 10 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- Jason Sperry
Rectal Cancer
Open or Laparoscopic Mesolectal Excision in Low Rectum Cancer
To compare the open approach and the laparoscopic-assisted approach of dissection of lateral lymph nodes in low advanced rectal cancer patients with clinically suspected nodal metastases in terms of safety, technical feasibility…
- Trial name
- NCT04561830
- Testing
- laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Acute GVHD
Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)
The purpose of this research study is to evaluate tacrolimus plasma concentrations in patients who will undergo an allogeneic hematopoietic stem cell transplant (HCT).
- Trial name
- NCT04645667
- Testing
- Tacrolimus
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
PEEP by Lung Ultrasound, PEEP With Dynamic Compliance
Postoperative Diaphragm Function in Pediatric Laparoscopic Abdominal Surgery Using Compliance and PEEP Guided by Lung Ultrasound
Protective ventilation strategies and alveolar recruitment maneuvers (ARM) are employed in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) to improve oxygenation, prevent alveolar collapse…
- Trial name
- NCT07126067
- Testing
- Lung Ultrasound and PEEP Application, Application of PEEP with Dynamic Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Konya City Hospital
Coronary Artery Disease
DES Versus BiOSS LIM - POLBOS II Study
Coronary bifurcation lesions pose therapeutic problems during percutaneous coronary interventions (PCI) and are associated with higher rates of periprocedural complications as well as higher rates of in-stent restenosis and stent…
- Trial name
- POLBOS II (NCT02198300)
- Testing
- Coronary angioplasty with stent implantation, Dual antipletlet therapy (DAPT)
- Where
- Poland
- Volunteers
- 202 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Heart Disease, Cancer
Promotora-based Latino Family CVD Risk Reduction
This family environment-focused health behavior change intervention is being carried out by extensively trained community health workers (promotores) familiar with the community in East Los Angeles.
- Trial name
- NCT01714271
- Testing
- Home environs-based lifestyle counseling, Cancer early detection
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Smoking
Feasibility of Conducting a Pilot Telehealth Study Assessing the Removal of Filter Ventilation on Smoking Behavior and Biomarkers in Menthol Smokers Switched to Non-menthol Cigarettes
This decentralized clinical trial assesses the feasibility of conducting a tobacco product evaluation study remotely via telehealth visits and mailed samples.
- Trial name
- NCT04514471
- Testing
- Minimally Ventilated non-menthol cigarettes, Ventilated non-menthol cigarettes
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Consumer Behavior
Understanding Adoption for Clean Cookstoves: A Demand Study
The aim of the Adoption study is to determine how best to encourage people to adopt clean cookstoves in order to diminish the global health risk of household air pollution.
- Trial name
- NCT04454944
- Testing
- LPG subsidy, Distance allocation
- Where
- 2 sites in United States, Ghana
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- Columbia University
De Novo Lipogenesis (DNL)
Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis
This proof of concept- study is to measure de novo lipogenesis (DNL) non-invasively in exhaled breath in overnight-fasted humans by triggering feeding response by deuterium resolved mass spectrometry.
- Trial name
- D2OBREATH (NCT05274334)
- Testing
- Assessment of de novo lipogenesis non-invasively in exhaled breath
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Advanced Solid Tumor
Evaluation of the Added Value of a Large Molecular Profiling Panel Versus a Limited Molecular Profiling Panel in Advanced Solid Tumors.
The PROFILER 02 program is a multicenter, randomized, prospective cohort study aiming to compare the clinical relevance of a large Next-generation sequencing (NGS) panel (FondationOne or FOne panel) versus a limited NGS panel…
- Trial name
- PROFILER 02 (NCT03163732)
- Testing
- Blood and tumor samples
- Where
- 15 sites in France
- Volunteers
- 341 people
- Sponsor
- Centre Leon Berard
Athletic Performance, Athletic Performance Enhancement
Bench Press During Squat Conditioning and PAPE
The goal of this clinical trial is to learn whether adding a moderate-load bench press exercise during the recovery periods between sets of back squats affects subsequent jumping performance in competitive male basketball…
- Trial name
- NCT07765732
- Testing
- Back Squat Conditioning Activity, Bench Press During Inter-Set Recovery
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Use of Power Wheelchairs and Power Seat Functions
Powered Seating Function Usage Among Veterans - Compliance and Coaching
The purpose of this randomized control study is to evaluate the use of electric powered wheelchairs and powered seating function patterns of Veterans to determine how usage patterns relate to activity, participation, and seating…
- Trial name
- NCT00839098
- Testing
- Instruction Group: Power seat function usage instruction- verbal and written instruction, Instruction and Virtual Coach Group: Power seat function usage instruction- verbal, written, and virtual coach
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Kwashiorkor
The Role of Sulfur Amino Acids in Risk of Kwashiorkor
This observational cross-sectional study is investigating if young children in populations with higher prevalence of kwashiorkor malnutrition have lower dietary sulfur amino acid intake than populations with lower prevalence of…
- Trial name
- NCT03520621
- Testing
- No intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Tufts University
Epidural Analgesics for Comparison
A Comparative Study Between Lumbar Epidural Analgesia Versus Local Infiltration Anesthesia Combined With Dexmedetomidine Intravenous Infusion in Endoscopic Lumbar Discectomy Surgeries: A Retrospective Study
The goal of this observational study is to compare the effectiveness and patient satisfaction of local anesthesia combined with intravenous Dexmedetomidine versus epidural anesthesia in endoscopic lumbar discectomy surgeries
- Trial name
- NCT07088016
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Gastro-esophageal Reflux Disease
Nociceptors, Neurotrophic Factors and Cytokine Expression in Gastroesophageal Reflux Disease
Transient receptor potential vanilloid-1 (TRPV1) receptor and proteinase-activated receptor 2 (PAR2) have been implicated in the mechanism of acid induced inflammation in gastroesophageal reflux disease (GERD).
- Trial name
- NCT02114216
- Testing
- endoscopic mucosal biopsy
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Musculoskeletal Manipulations, Primary Prevention
Effects of Perineal Massage (PERMAS)
Perineal massage increases elasticity of myofascial perineal tissue and decreases the burning and perineal pain during labour, thus optimizing child birth, although an application protocol has not been standardized yet.
- Conditions
- Musculoskeletal Manipulations, Primary Prevention, Obstetric Labor Complications, Physical Therapy Modalities
- Trial name
- PERMAS (NCT05114811)
- Testing
- Self-provided perineal massage, Physiotherapist perineal massage: manual and instrumental (with EPI-NO)
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Rheumatic Diseases, Temporomandibular Joint Dysfunction
Treatment in Individuals With Rheumatoid Arthritis Who Have Temporomandibular Joint Dysfunction
This study was conducted to investigate the effect of manual therapy applications on pain, range of motion and joint position sense in individuals with rheumatoid arthritis who have temporomandibular joint dysfunction.
- Conditions
- Rheumatic Diseases, Temporomandibular Joint Dysfunction, Manuel Therapy
- Trial name
- NCT07171671
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sanko University
Human Immunodeficiency Virus (HIV) Infection
Interventions to Improve HIV Antiretroviral Therapy Adherence
This study will explore whether financial incentives, reminders, information about HIV/AIDS and its treatment and anti-stigma counseling help improve anti-retroviral therapy (ART) adherence among HIV infected individuals in a…
- Trial name
- NCT03618511
- Testing
- Financial Incentive, Reminders, Financial Incentive and Reminders
- Where
- Mozambique
- Volunteers
- 914 people
- Sponsor
- University of Michigan
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