Clinical trials: Ketorolac
Conjunctivitis, Viral
Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Acute Viral Conjunctivitis
The purpose of this study is to evaluate the evolution of the symptoms of acute viral conjunctivitis using preservative free ketorolac trometamol 0.45% associated with carboxymethylcellulose compared with isolated use of…
- Trial name
- NCT01799863
- Testing
- Ketorolac trometamol 0.45% with carboxymethylcellulose, Preservative free artificial tear
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Fundação Altino Ventura
Analgesia
Analgesia After Total Knee Arthroplasty
The recovery from knee replacement surgery often involves a significant amount of pain. The best way to prevent/treat this pain is unknown.
- Trial name
- NCT00869037
- Testing
- Periarticular Injection, CFNB + Posterior Capsular Injection
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Pain, Acute
Prehospital Analgesia in Adults Using Inhaled Methoxyflurane Study
This study is about a new pain relief medication called methoxyflurane. Pain from injuries, like broken bones, is a big reason people call ambulances.
- Trial name
- NCT06392087
- Testing
- Methoxyflurane, Standard Care
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Postoperative Pain, Bariatric Surgery Candidate
Intravenous Ibuprofen Versus Ketorolac in Bariatric Surgery
The aim of the current study is to compare the analgesic effects of both drugs in patients with obesity undergoing bariatric surgery.
- Trial name
- NCT05801900
- Testing
- Ketorolac group, Ibuprofen group
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Cairo University
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Acute Migraine Headache
Oral Medications for the Management of Acute Migraine Headache in the Emergency Department
The goal of this pilot randomized control trial is to assess the feasibility of our patient recruitment and data collection strategy ahead of a full scale RCT investigating the efficacy of oral v.
- Trial name
- NCT05983354
- Testing
- Oral metoclopramide and ibuprofen, Intravenous metoclopramide and ketorolac
- Sponsor
- Health Sciences North Research Institute
Non-small Cell Lung Cancer, Renal Cell Carcinoma
Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma
This is a pilot study of biomarker evaluation and safety of pre-incisional ketorolac for patients undergoing surgical resection for non-small cell lung cancer and renal cell carcinoma.
- Trial name
- NCT04495894
- Testing
- Preoperative Ketorolac
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Pain, Postoperative, Lung Neoplasm
PATHOS Study Pain Assessment in Thoracic Oncologic Surgery
A randomized prospective trial to assess whether the use of loco regional anesthesia as adjuvant analgesic therapy is more effective of intravenous analgesia only.
- Trial name
- PATHOS (NCT03134729)
- Testing
- Ropivacaine for Serratus Plane Block (SPB)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Laparoscopic Gynecological Surgery
Bellomic PCA in Laparoscopic Gynecologic Surgery
In laparoscopic gynecological surgery, when intravenous patient-controlled analgesia (IV-PCA) device is used after surgery, the degree of postoperative side effects and pain control is compared when a combination of fentanyl and…
- Trial name
- NCT05489796
- Testing
- Fentanyl selector, Fentanyl continuous, Ketorolac continuous
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Bundang Hospital
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
Relief Efficacy of Lidocaine Versus Morphine for Acute Renal Colic in the Emergency Department
The opioid epidemic continues to be a major public health crisis in the United States. According to the Center for Disease Control, approximately 8 million Americans reported misusing prescription opioids in 2023, with over 5…
- Conditions
- Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia, Opioid Use During Medical Care
- Trial name
- RELIEF-RC (NCT07536594)
- Testing
- Lidocaine, Morphine 0,1 mg/kg
- Volunteers
- 250 people
- Sponsor
- Loma Linda University
Shoulder Osteoarthritis, Cuff Tear Arthropathy
Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty
Pain management following total shoulder arthroplasty is an important factor in determining patient outcomes and satisfaction. Interscalene brachial plexus blockade has been used successfully to minimize pain in the acute…
- Conditions
- Shoulder Osteoarthritis, Cuff Tear Arthropathy, Massive Rotator Cuff Tear
- Trial name
- NCT04415931
- Testing
- Local infiltration analgesia, Interscalene block
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Missouri-Columbia
Anesthesia, Surgery
Association Between Clinical Effect of Continuous Morphine Administration After Surgery and Pharmacogenetics
Identification of the genetic polymorphisms that could be correlated either with a better clinical response or with a major predisposition of patients to develop tolerance and/or side effects to the treatment with morphine.
- Trial name
- NCT01233219
- Testing
- morphine chlorhydrate
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Scorpion Stings, Pain
Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings
The cases of scorpion stings are matters of medical importance, where Mexico is considered as one of the main countries of such public health problem.
- Conditions
- Scorpion Stings, Pain, Analgesic
- Trial name
- NCT03943199
- Testing
- Visual Analogue Scale for pain
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Mexican Red Cross
Morbid Obesity, PCA
Dual-chamber Patient-controlled Analgesia for Postoperative Recovery
Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV.
- Conditions
- Morbid Obesity, PCA, Analgesia, PONV
- Trial name
- NCT07051109
- Testing
- multimodal analgesia via dual-chamber PCA, single regimen (only fentanyl)
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Bundang Hospital
Low Back Pain
Morphine Versus Ketorolac in Low Back Pain
The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in low back pain.
- Trial name
- NCT02782286
- Testing
- Ketorolac, Morphine
- Volunteers
- 100 people
- Sponsor
- Loredana Ghinea
Pain
Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia
One dose of either gabapentin or placebo will be given to patients prior to thoracotomy. Patients will also receive an epidural infusion, intravenous patient-controlled analgesia with fentanyl, oral acetaminophen and intravenous…
- Trial name
- NCT00588159
- Testing
- Gabapentin, Diphenhydramine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Michelle Kinney
Femoracetabular Impingement, Hip Arthroscopy
Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy
The goal of this clinical trial is to learn whether the medication ketorolac can help manage pain after hip arthroscopy as well or better than the standard opioid-based pain medications.
- Trial name
- NCT07037888
- Testing
- Ketorolac, Control (Standard treatment), Omeprazole
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Pain, Ketorolac
Atomized Intranasal Ketorolac at 30 mg Versus 20 mg for the Treatment of Acute Pain in the Emergency Department
This study aims to compare the analgesic effectiveness and side effects of intranasal ketorolac at 30 mg Versus 20 mg for the Treatment of Acute moderate and severe Pain in the Emergency Department.
- Conditions
- Pain, Ketorolac, Intranasal Drug Administration
- Trial name
- NCT07816302
- Testing
- 20mg intranasal ketorolac, 30mg Intranasal Ketorolac
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug)
Pain Control After Lumbar Spine Fusion
The purpose of this randomized controlled trial is to determine if patients who receive non-steroidal anti-inflammatory medications (NSAIDs) following elective lumbar spinal fusion have increased rates of symptomatic nonunion…
- Conditions
- Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug), Postoperative Pain
- Trial name
- NCT06484192
- Testing
- Naproxen 500 Mg, Ketorolac, OxyCODONE 5 mg Oral Tablet
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics