Clinical trials: Ketorolac
Pain, Side Effects
Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum
Postoperative pain management is a major problem after repair of pectus excavatum.Various methods of pain management have been introduced.
- Trial name
- NCT01908491
- Testing
- IV PCA, Continuous wound infusion
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Cataract
Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size
The objective of this study is to compare the maintenance of intraoperative mydriasis during cataract surgery between two drugs: epinephrine, which has routinely been used for decades, and Omidria, a newly FDA approved…
- Trial name
- NCT02895035
- Testing
- Phenylephrine-ketorolac, Epinephrine
- Volunteers
- 59 people
- Sponsor
- Milton S. Hershey Medical Center
Total Hip Arthroplasty, Postoperative Pain
Pericapsular Nerve Group (PENG) Block Versus Periarticular Injection for Pain Management After Total Hip Arthroplasty
Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. The pericapsular nerve group (PENG) block has been recently introduced a new technique for blockade of the articular…
- Trial name
- NCT04981236
- Testing
- Pericapsular nerve group block, Periarticular block
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Recurrent Acute Tonsillitis
KITS Study -Ketorolac In Tonsillectomy Surgery: a Double Blinded, Randomized Clinical Trial
Our group wishes to test the novel hypothesis that intraoperative use of ketorolac in pediatric patients undergoing tonsillectomy reduces post-operative nausea and vomiting, postoperative pain scores, subsequent narcotic use, and…
- Trial name
- KITS (NCT01498796)
- Testing
- Ketorolac, Normal Saline
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- University of Alberta
Myopes Who Have Undergone PRK.
Time Serial Analysis on Preemptive Analgesia of Preoperative Topical Diclofenac and Ketorolac in Photorefractive Keratectomy(PRK)
The investigators performed this study to investigate pain prevention of preoperative topical nonsteroidal anti-inflammatory drug (NSAID) in photorefractive keratectomy(PRK) using time serial pain scoring.
- Trial name
- NCT01761071
- Testing
- topical ketorolac 0.5% (Acular®, Allergan Inc, Irvine, CA), topical diclofenac 0.1% (Voltaren®, Novartis, Bern, Switzerland)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Yonsei University
Elective Bilateral Myringotomy
Sublingual Ketorolac Compared to Intranasal Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Bilateral Myringotomy
The investigators aim to compare intranasal dexmedetomidine in a dose of 1ug.kg-1 with sublingual ketorolac in a dose of 1mg.kg-1 on postoperative behaviour in those children undergoing BMT during their PACU stay
- Trial name
- NCT03742180
- Testing
- intranasal dexmedetomidine, sublingual ketorolac
- Where
- Egypt
- Sponsor
- Mansoura University
IUD Insertion Pain
Oral Ketorolac for IUD Pain Reduction
To determine if oral ketorolac given at different timepoints prior to intrauterine device (IUD) insertion influences pain experienced during this procedure.
- Trial name
- NCT06853327
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cystoid Macular Edema After Phacoemulsification
Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients
The aim of the study is determining the prophylactic effect of ketorolac tromethamine drop 0.5% eye drop on the functional and anatomical ocular characteristics of the diabetic patients after the phacoemulsification surgery.
- Trial name
- NCT03551808
- Testing
- using of Ketorolac Tromethamine Eye Drop
- Where
- Iran
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Preeclampsia, Gestational Hypertension
Postpartum NSAIDS and Maternal Hypertension
Previous studies have suggested that NSAID use causes an increase in blood pressure. Further, blood pressure elevation has been noted in women with pregnancy related hypertensive disease during the postpartum period.
- Conditions
- Preeclampsia, Gestational Hypertension, Superimposed Preeclampsia, Chronic Hypertension in Obstetric Context
- Trial name
- NCT03824119
- Testing
- Ibuprofen 600 mg, Standard Postpartum Care without NSAIDs
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Opioid Withdrawal
Pregabalin for Opiate Withdrawal Syndrome
It is a single blind randomized symptom triggered study to assess efficacy and safety of pregablin combined with the symptom triggered treatment for opiate withdrawal syndrome vs.
- Trial name
- NCT03017430
- Testing
- Pregabalin, Clonidine, Doxylamin
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- St. Petersburg Bekhterev Research Psychoneurological Institute
Arthroplasty, Replacement, Hip
Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study
The purpose of this study is to determine whether wound infiltration with following single-shot bolus injection with local anesthetic and NASIDs are effective in the treatment of postoperative pain after total hip replacement…
- Trial name
- NCT00289419
- Testing
- Epidural Ropivacaine, morphine, Ropivacaine, Ketorolac and Adrenaline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Pregnancy Related, Narcotic Use
Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section
This randomized controlled trial will compare two different approaches to patient recovery after cesarean section: the current standard of care versus an alternate management protocol.
- Trial name
- NCT03330119
- Testing
- Alternate Management, Control
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Brest, Norman A., M.D.
Knee Joint Arthritis, Knee Joint Arthroplasty
Motor Sparing Block vs. Peri-Articular Catheters
This study is designed to determine if one anaesthetic modality, either motor sparing nerve block or peri-articular local infiltration anaesthesia with infusion, is superior in providing postoperative analgesia following total…
- Trial name
- NCT01503528
- Testing
- Motor Sparing Nerve Block, Peri-articular Catheters
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain After Stapled Haemorrhoidopexy
Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy
This study wants demonstrate that the use of 0.4% nitroglycerin ointment can reduce the postoperative pain related to anorectal spasm (anismus) while performing a stapled haemorrhoidopexy.
- Trial name
- TAGASH (NCT01279551)
- Testing
- 0.4% nitroglycerin ointment, lidocaine cloridrato 2.5% ointment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Symptomatic Irreversible Pulpitis
Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
The aim of this study is to determine whether inferior alveolar nerve block of ketorolac and lidocaine would improve the success rate in teeth with symptomatic irreversible Pulpitis.
- Trial name
- IANB (NCT03410212)
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Cataract
Ketorolac vs. Steroid in the Prevention of CME
Evaluate if the incidence of sub clinical CME can be significantly reduced by use of peri-operative Acular LS plus Pred Forte when compared with Pred Forte alone in normal cataract patients.
- Trial name
- NCT00348244
- Testing
- Ketorolac, Prednisolone Acetate
- Where
- United States
- Sponsor
- Innovative Medical
Pain
Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy
Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours.
- Trial name
- NCT01242644
- Testing
- pain pump containing ropivacaine, saline pain pump with injectable medication, ropivacaine, ketorolac , morphine sulfate
- Volunteers
- 48 people
- Sponsor
- University of South Alabama
Secondary Malignant Neoplasm of Liver, Liver Diseases
Spinal Versus Epidural Analgesia in Laparotomic Liver Surgery
The purpose of this study is to evaluate the efficacy of spinal analgesia for minor laparotomic hepatectomy compared with epidural analgesia, monitoring visual analog scale (VAS).
- Conditions
- Secondary Malignant Neoplasm of Liver, Liver Diseases, Liver Neoplasms
- Trial name
- NCT02647047
- Testing
- Spinal analgesia, Epidural analgesia, Transversus Abdominis Plane block
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Ospedale San Raffaele
Pain, Postoperative
Paracetamol Compared With Ketorolac for Post-operative Analgetic
Post-operative analgetic modalities vary between center to center, especially in Indonesia. Considerations include potency/effectivity of the analgetics to achieve adequate pain control as soon as possible, reducing the total…
- Trial name
- NCT05523102
- Testing
- Paracetamol, Ketorolac
- Where
- Indonesia
- Volunteers
- 85 people
- Sponsor
- Universitas Indonesia