Clinical trials: Ketorolac
Cataract, Surgery
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the…
- Conditions
- Cataract, Surgery, Compliance, Patient, Compliance, Medication
- Trial name
- NCT05157113
- Testing
- Dropless Regimen, Standard Regimen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Bowel Obstruction
A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome extended-release injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL therefore possibly…
- Trial name
- IMPROVE-Open (NCT01507220)
- Testing
- morphine sulfate, bupivacaine liposome extended-release injectable suspension
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Nausea and Vomiting, Colorectal Neoplasms
Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery
Background: PONV is one of the prevalent discomforts in the early phase of recovery after surgery. Evidence suggests that the stimulation of the P6 acupuncture point can reduce the occurrence of PONV.
- Trial name
- AcuPONV (NCT02509143)
- Testing
- High-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Yangsan Hospital
DeQuervains Tenosynovitis, Lateral Epicondylitis
Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders
The primary objective of this study is to compare local corticosteroid hand and elbow injections to placebo or ketorolac to determine if there is an equal or better reduction of symptoms for common orthopaedic upper extremity…
- Conditions
- DeQuervains Tenosynovitis, Lateral Epicondylitis, Tennis Elbow, Trigger Finger
- Trial name
- NCT02266433
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- NYU Langone Health
Retraction of Colostomy
A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly reducing total…
- Trial name
- IMPROVE-IR (NCT01509638)
- Testing
- Group 1 Standard of Care, Group 2 EXPAREL
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Renal Colic, Flank Pain
Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients
This is a prospective interventional study examining the effect of ketorolac at doses of 15mg versus 30 mg for duration of analgesia in emergency department patients with suspected renal colic.
- Conditions
- Renal Colic, Flank Pain, Emergencies, Analgesia
- Trial name
- NCT05776953
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hackensack Meridian Health
Renal Colic
Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control
The aim of this study is the comparison of efficacy of intravenous ketorolac and intranasal desmopressin in renal colic patients pain control.
- Trial name
- NCT02937896
- Testing
- Desmopressin, Ketorolac, Normal Saline
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Postoperative Pain, Knee Replacement Arthroplasty
Management of Postoperative Pain After Total Knee Replacement.
The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.
- Trial name
- NCT01163214
- Testing
- Nerve Block, Periarticular Injection
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mark J. Spangehl, M.D.
Hematoma Postoperative
The Effect of Intra-operative Ketorolac on Hematoma Rates in Breast Reduction Surgery
It has been a longstanding teaching in plastic surgery that intra-operative ketorolac use for postoperative pain control increases hematoma and bleeding in breast reduction surgery.
- Trial name
- NCT03535116
- Testing
- Ketorolac, Saline
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Dr. Chandran Medical Prof Corp
Cataract
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
- Trial name
- NCT00333255
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Inflammation Biomarkers, Quality of Recovery (QoR-15)
Comparison of Inflammatory Factors, Pain Scale, and Postoperative Recovery Quality (QOR - 15) in Patients Undergoing Colorectal Cancer Surgery with Conventional General Anesthesia Techniques Compared to General Anesthesia Combined with Epidural Anesthesia At Prof. Ngoerah Hospital
Surgery can increase IL-6 cytokines, triggering inflammation and metastasis. The combination of general and epidural anesthesia has the potential to suppress IL-6, improve the tumor microenvironment, provide analgesia, and…
- Conditions
- Inflammation Biomarkers, Quality of Recovery (QoR-15), Visual Analog Pain Scale
- Trial name
- NCT06784258
- Testing
- General Anesthesia (control group), General Anesthesia combined with epidural anesthesia
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Udayana University
Pain
Local Infiltration Analgesia During Total Knee Arthroplasty
The primary objective is to evaluate whether local infiltration analgesia (LIA) will reduce oxycodone consumption during the first 48 postoperative hours in patients undergoing total knee arthroplasty (TKA).
- Trial name
- LIA (NCT01305733)
- Testing
- The injectant mixture consists of 150 mg levobupivacaine mixed with 30 mg ketorolac and 0.5 mg adrenaline, saline injection
- Where
- 2 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Pain
Intravenous Lidocaine and Ketorolac for Pain Management
The literature regarding analgesic modalities, their combinations and routes of administrations for patients with pain related to renal colic is expanding.
- Trial name
- NCT02902770
- Testing
- Lidocaine, Ketorolac Tromethamine, Normal Saline Drip
- Volunteers
- 150 people
- Sponsor
- Antonios Likourezos
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Acute Renal Colic
Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management.
Introduction: Pain is a common reason for individuals to seek health care, especially emergency care. Ketorolac has numerous advantages over other pain medications, especially the opioids.
- Trial name
- Ink-Arc (NCT04441762)
- Testing
- Intravenous Ketorolac Tromethamine, Intranasal Ketorolac Tromethamine
- Where
- Oman
- Volunteers
- 171 people
- Sponsor
- Oman Medical Speciality Board
Knee Osteoarthritis
Comparing Intra-articular Corticosteroid to Intra-articular Ketorolac Knee Injections
This study will compare the efficacy of intra-articular betamethasone injection to intra-articular ketorolac injection for symptomatic treatment of knee osteoarthritis in an equivalence study using a double-blinded, randomized…
- Trial name
- NCT02612272
- Testing
- Ketorolac, Betamethasone
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Post Vasectomy Pain
Intranasal Ketorolac Tromethamine (SPRIX) as a Short Term Pain Management of Post-Vasectomy Pain
To evaluate the efficacy, tolerability and safety of intranasal ketorolac tromethamine (SPRIX) as an option for pain management in post vasectomy patients.
- Trial name
- NCT02000388
- Testing
- Ketorolac Tromethamine, Standard of Care
- Volunteers
- 15 people
- Sponsor
- Citrus Valley Medical Research, Inc.
Post Operative Pain
Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy
The aim of the present study was to compare the effectiveness of transmuscular Quadratus Lumborum block using Bupivacaine versus Bupivacaine- Dexamethasone in providing analgesia in patients undergoing laparoscopic…
- Trial name
- NCT03956966
- Testing
- TQL block with saline, TQL block with Bupivacaine, TQL block with Bupivacaine and dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Analgesia, Urolithiasis
Efficacy of Pethidine, Ketorolac And Xylocaine Gel As Analgesics For Pain Control In Shockwave Lithotripsy
A randomised prospective trial comparing the efficacy of pethidine, Ketorolac, and Xylocaine gel as analgesics for pain control in shockwave lithotripsy.
- Trial name
- NCT03032458
- Testing
- Pethidine, Ketorolac, Xylocaine Gel
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Mansoura University