Clinical trials: Ketorolac
DME
Short-term Additive Effect of Topical Ketorolac on the Management of Diabetic Macular Edema With Intravitreal Bevacizumab
Purpose: To evaluate the short-term effect of adding topical ketorolac to the management of diabetic macular edema (DME) with intravitreal bevacizumab (IVB).
- Trial name
- NCT04119921
- Testing
- prescription topical ketorolac in group 1, prescription artificial tear in group 2, prescription topical ketorolac in group 2
- Where
- Iran
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Postoperative Pain
Local Infiltration Analgesia Following Unicompartmental Knee Arthroplasty
The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect hospital stay.
- Trial name
- NCT00653926
- Testing
- ropivacaine, ketorelac and epinephrine, saline
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Mastectomy, Modified Radical
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT07257874
- Testing
- bupivacaine 0.5% injection, Ketorolac 30 mg IV
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Anesthesia
Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT
Several studies demonstrated the effectiveness of OFA in patients undergoing non-cardiac surgery. Preoperative use of Cox inhibitors, GABA analogues and acetaminophen have been shown to decrease use of opioids postoperatively .
- Trial name
- NCT04648540
- Testing
- Dexmedetomidine 0.5 mic/kg/h, Fentanyl 1 mic/kg/hr
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Knee Replacement, Total
Implementation of a Pain Management Protocol for Total Knee Arthroplasty
Study question: Is there an ideal combination of intraoperative long acting analgesics (periarticular infiltration (PI), femoral nerve block (FB) and intrathecal opioids (IO)) to optimize post-operative functional recovery…
- Trial name
- NCT02474654
- Testing
- Bupivicaine, Fentanyl, Epimorphine
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Health Sciences North Research Institute
Knee Arthroplasty, Pain Management
Gonyautoxins Local Periarticular Injection for Pain Management After Total Knee Arthroplasty
The aim of this study is to demostrate the eficcacy in pain control management after total knee arthroplasty of Gonyautoxin. Local administration during surgery of Gonyautoxin before wound closure can achieved better pain control…
- Trial name
- Toxin (NCT03025594)
- Testing
- Gonyautoxins, Chirocaine ketorolac epinephrine
- Where
- 2 sites in Chile
- Volunteers
- 64 people
- Sponsor
- maximiliano barahona vasquez
Breast Cancer, Postoperative Pain, Acute
Effect of Continuous Erector Spinae Plane Block With Ropivacaine on Postoperative Pain and NF-κB Levels After Mastectomy
This study aims to evaluate the effect of continuous erector spinae plane block (CESPB) using ropivacaine on postoperative pain in patients undergoing elective mastectomy.
- Trial name
- NCT07562945
- Testing
- Continuous Erector Spinae Plane Block, Ropivacaine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Aldy Aldy
Turbinate Surgery, Sphenopalatine Block
Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
Nasal turbinectomy surgeries are usually done as day case surgeries as most patients are young with unremarkable comorbidities. However, considerations are still present towards patients of old age or those suffering from obesity…
- Trial name
- SPG block (NCT07299630)
- Testing
- Balanced anesthesia, Lidocaine spray
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Pain
Intrathecal Ketorolac in Patients With Intrathecal Morphine Dose Escalation
The purpose of this study is to determine how the drug ketorolac, when given with the spinal morphine, affects pain.
- Trial name
- NCT00349401
- Testing
- ketorolac, morphine
- Sponsor
- Wake Forest University Health Sciences
Macular Edema, Cystoid
Effect of Prophylactic Ketorolac on CME After Cataract Surgery
The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone…
- Trial name
- NCT00335439
- Testing
- ketorolac tromethamine 0.5% (Acular®)
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Queen's University
Renal Colic
Morphine Versus Ketorolac in Renal Colic
The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in renal colic.
- Trial name
- NCT02782273
- Testing
- Ketorolac, Morphine
- Volunteers
- 100 people
- Sponsor
- Loredana Ghinea
Multiple Fracture Ribs
Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture Ribs
Rib fractures are common after blunt injury to the chest. Present in 10% of blunt trauma admissions. Pain associated with rib fractures can result in compromise of pulmonary function causing hypoxaemia or pneumonia, which may…
- Trial name
- NCT05975294
- Testing
- amixture 0.125% bupivicaine with fentanyl, 100 ml volume containing 80 mg of nalbuphine ,180 mg ketorolac, 24mg dexamethasone, 16 mg danset
- Volunteers
- 60 people
- Sponsor
- Sohag University
Bunionectomy, Orthopedic Surgery
Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy
To determine whether a single dose of intravenous lornoxicam is superior to intravenous placebo for management of post-operative pain in patients who have surgical removal of a bunion on the lower extremity.
- Trial name
- NCT00293631
- Testing
- Lornoxicam 8 mg, Lornoxicam 16 mg, Ketorolac 30 mg
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- POZEN
Trauma, Opioid Use
Relieving Acute Pain (RAP) Study: A Pilot Study
The United States (US) faces a crisis of pain management. According to the 2012 National Health Interview Survey, almost 50 million adults in the US reported having significant chronic or severe pain (Nahin 2015).
- Conditions
- Trauma, Opioid Use, Spine Fusion
- Trial name
- NCT03426137
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Laparoscopic Cholecystectomy
Kidney Function After Pneumoperitoneum and Analgesia
double blind study of kidney function of two groups of adult patients submitted to laparoscopic cholecystectomy and analgesia from tramadol associated to dipyrone or ketorolac
- Trial name
- NCT00914875
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Analgesia, Urolithiasis
Efficacy of Pethidine, Ketorolac And Xylocaine Gel As Analgesics For Pain Control In Shockwave Lithotripsy
A randomised prospective trial comparing the efficacy of pethidine, Ketorolac, and Xylocaine gel as analgesics for pain control in shockwave lithotripsy.
- Trial name
- NCT03032458
- Testing
- Pethidine, Ketorolac, Xylocaine Gel
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Mansoura University
Diabetic Retinopathy, Macular Edema
Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema
The purpose of this study is to determine the efficacy of ocular topic antiinflammatory therapy (sodic nepafenac at 0.1% or ketorolac at 0.5%) to treat center point thickness secondary to selective photocoagulation in diabetics…
- Trial name
- NCT00900887
- Testing
- Ketorolac, Nepafenac, Polietilenglicol 400, propilenglicol
- Where
- Mexico
- Volunteers
- 84 people
- Sponsor
- Hospital Juarez de Mexico
Chronic Migraine, Cluster Headache
Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache
The purpose of this study is to evaluate the safety and efficacy of intra-arterial (IA) delivery of Dexamethasone and Ketorolac into the arteries supplying the sphenopalatine ganglion (SPG) - a collection of neurons that plays an…
- Conditions
- Chronic Migraine, Cluster Headache, Trigeminal Neuralgia
- Trial name
- NCT04353505
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Headache
Metoclopramide Versus Ketorolac for Tension-type Headache
Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type…
- Trial name
- NCT01011673
- Testing
- Metoclopramide, Ketorolac
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Montefiore Medical Center
Post Operative Anterior Chamber Inflammation (Flare)
A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)
Approximately 50 patients undergoing cataract surgery will be randomized in an even allocation (1:1) into two treatment groups, either ketorolac 0.45% BID or bromfenac 0.09% BID.
- Trial name
- NCT01023724
- Testing
- Ketorolac Tromethamine 0.45%, Bromfenac 0.09%
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute