Clinical trials: Ketorolac
Pain, Chronic
CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone
this study investigator will resaearsh about the efficacy of addition of ketorlac or dexamethasone to alcohol in ablation of ganglion impar in pelvic tumour to asses thier efficacy in increasing the intensity or the duration of…
- Trial name
- NCT03789227
- Testing
- ganglion impar block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Pain
Multimodal Pain Management for Cesarean Delivery
Opioid use and abuse has become a major medical problem in the United States. Over prescription of opioid medications is a major contributor to this growing problem.
- Trial name
- NCT02922985
- Testing
- Intravenous acetominophen, Ketorolac, intramuscular, Bupivacaine, subcutaneous
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pain, Postoperative Pain
Presternal Bupivacaine Plus Magnesium Sulfate Infusion After Cardiac Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT02731950
- Testing
- Magnesium Sulfate and Bupivacaine 0.125%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Post-surgical Pain
Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs.
- Trial name
- NCT03599089
- Testing
- CA-008, Ketorolac, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 147 people
- Sponsor
- Concentric Analgesics
Fentanyl, Ketorolac
Fentanyl Versus Ketorolac as an Adjuvant to Peribulbar Block for Anterior Segment Surgeries
This study aims to compare the efficacy of ketorolac and fentanyl as adjuvants to local anesthetics for anterior segment surgeries of the eye.
- Conditions
- Fentanyl, Ketorolac, Adjuvant, Peribulbar Block
- Trial name
- NCT07141589
- Testing
- Lidocaine + Bupivacaine + Hyaluronidase, Fentanyl + Lidocaine + Bupivacaine + Hyaluronidase, Ketorolac + Lidocaine + Bupivacaine + Hyaluronidase
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Cairo University
Osteoarthritis of the Knee
Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1.
- Trial name
- NCT00562627
- Testing
- ropivacaine, adrenaline, ketorolac
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Asker & Baerum Hospital
Vaso-Occlusive Pain Episode in Sickle Cell Disease, Sickle Cell Disease (SCD)
Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis
The goal of this study is to learn if Ketamine works more efficiently, as compared to Opioids, for Sickle Cell Pain The main questions it aims to answer are: Does Ketamine lower the number of times participants need to be…
- Trial name
- NCT07682662
- Testing
- Standardized Low-dose bolus IV Ketamine within 30 minutes of arrival and every 1 hour as needed for max of 3 doses., Standard Care (in control arm)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Mississippi Medical Center
Pain Postoperative, Total Knee Anthroplasty
Comparative Analgesic Effect After Total Knee Arthroplasty Between Intraosseous and Peri-articular Injection
The goal of this RCT is to compare analgesic effect after total knee arthroplasty between intraosseous multimodal analgesic agent injection versus periarticular injection.
- Conditions
- Pain Postoperative, Total Knee Anthroplasty, Functional Outcomes
- Trial name
- NCT06800846
- Testing
- Intraosseous Morphine, Periarticular Injection
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Thammasat University Hospital
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Acute Pain Due to Trauma
Ibuprofen Versus Ketorolac by Mouth in the Treatment of Acute Pain From Osteoarticular Trauma
Pain is the leading cause of access to the paediatric emergency department (ED) and present in up to 78% of cases. Acute osteoarticular traumatic pain is often treated inadequately, and there is little data about the best…
- Trial name
- IbuKet (NCT04133623)
- Testing
- Ketorolac, Ibuprofen
- Where
- 3 sites in Italy
- Volunteers
- 212 people
- Sponsor
- IRCCS Burlo Garofolo
Pain, Pain, Postoperative
Study of Whether 15 mg Dose of Ketorolac IV is as Effective as a 30 mg Dose.
The primary aim of this study is to show the non-inferiority of 15 mg intraoperative dose of ketorolac as compared to the standard 30 mg ketorolac by looking at the VAS scores 4 hours after an adult spine surgery.
- Trial name
- NCT01230463
- Testing
- Ketorolac Tromethamine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Osteoarthritis, Knee
Periarticular Multimodal Drug Injections in Total Knee Arthroplasty
The purpose of this study is to determine whether periarticular multimodal drug injection (PMDI) would provide additional benefits in patients after total knee arthroplasty (TKA) for whom contemporary pain control protocols using…
- Trial name
- NCT00901628
- Testing
- ropivacaine, morphine sulfate, ketorolac
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Seoul National University Hospital
Total Knee Arthroplasty
Total Knee Prosthesis With Continuous Block of Adductor Canal and Outcome
Aim of this study is to evaluate the effects of the adductor canal block on the early and medium term ( 1 month) rehabilitation compared to the continuous femoral block commonly used in the knee prosthesis.
- Trial name
- NCT02082067
- Testing
- Adductor canal, Femoral, Spinal Anesthesia
- Where
- Italy
- Sponsor
- ASST Gaetano Pini-CTO
Pain
Efficacy of Spontaneous Laughter in the Postoperative Treatment of Children
The purpose of this study is to determine the efficacy of laughter therapy in children to improve postoperative, evaluating the intensity of postoperative pain, anxiety and hospital stay.
- Trial name
- NCT02563587
- Testing
- Laughter therapy, Accompaniment without causing the laughter of children., Conventional treatment
- Where
- Mexico
- Volunteers
- 210 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Malocclusion, Pain, Acute
Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment
Due to the high prevalence of malocclusions in Mexico and the existing concern to improve aesthetics, function (chewing), or both, patients resort to orthodontic treatment.
- Trial name
- NCT05383820
- Testing
- Ketorolac
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Post Operative Pain
Morphine PK Subgroup Analysis
This study was originally undertaken to evaluate the analgesic efficacy of an intravenously administered dose of ketorolac compared with intravenous morphine in the relief of acute, postoperative pain in children admitted to the…
- Trial name
- NCT01322191
- Testing
- Morphine
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bowel Obstruction
A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly reducing total…
- Trial name
- IMPROVE-Lap (NCT02058290)
- Testing
- IV morphine sulfate or Sponsor-approved equivalent, EXPAREL
- Where
- 6 sites in United States
- Volunteers
- 122 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pharmacokinetics
Administration of Tramadol and Ketorolac Separately and Simultaneously to Assess a Potential Pharmacokinetic Interaction
Tramadol (Tradol) and ketorolac (Dolac) are marketed products to treat acute pain. This study was performed to determine if both medications can be given to a patient simultaneously without a change of the products'…
- Trial name
- NCT03767036
- Testing
- Tramadol hydrochloride 25 mg capsule, Ketorolac Tromethamine 10 mg tablet
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Rotator Cuff Tear
Nonopioid Analgesia After Rotator Cuff Repair
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a…
- Trial name
- NCT03818919
- Testing
- Celecoxib, Ketorolac, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Prostatectomy, Pain
Impact of Perioperative Analgesia in Prostatectomy Patients on Early Quality of Recovery (SPITALIDO)
The rationale behind this RCT is to assess within 24 hours after surgery the quality of recovery of prostatectomy patients treated with 3 different analgesia concepts (intraoperative spinal analgesia, transversus abdominis plane…
- Trial name
- SPITALIDO (NCT03618693)
- Testing
- Spinal anesthesia, TAP Block, Standard
- Where
- Switzerland
- Volunteers
- 142 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern