Clinical trials: Ketorolac
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Pain
Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
The purpose of this study is to determine if the infusion of the local anesthetic ropivacaine (a numbing medicine) and the non-steroidal anti-inflammatory drug ketorolac (a pain killer similar to ibuprofen) through a catheter…
- Trial name
- NCT02829944
- Testing
- Ropivacaine, Ketorolac
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Postoperative Nausea and Vomiting
The Effect of PCA on PONV After Microvascular Decompression
This study is a randomized, controlled, double-blinded, and parallel design study. A total 94 patients will be randomized to receive ketorolac or fentanyl based patient-controlled analgesia after microvascular decompression…
- Trial name
- NCT05189704
- Testing
- NSAID, Opioid
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Post Operative Pain
Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy
The aim of the present study was to compare the effectiveness of transmuscular Quadratus Lumborum block using Bupivacaine versus Bupivacaine- Dexamethasone in providing analgesia in patients undergoing laparoscopic…
- Trial name
- NCT03956966
- Testing
- TQL block with saline, TQL block with Bupivacaine, TQL block with Bupivacaine and dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Acute Pancreatitis
Treatment of Acute Pancreatitis With Ketorolac
Patients with acute pancreatitis will be randomly assigned in either study group to receive oral (injection) Ketorolac or the control group. In patients who cannot tolerate oral medications, ketorolac injection will be used.
- Trial name
- NCT02885441
- Testing
- Ketorolac
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Ilam University of Medical Sciences
Gall Stone Disease
Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy
Comparison of intraoperative infusion of lidocaine and esmolol in the postoperative requirement of opioid for postoperative pain management after laparoscopic cholecystectomy to decrease opioid related side effects and enhance…
- Trial name
- NCT02327923
- Testing
- Lidocaine, Esmolol, Paracetamol
- Where
- Nepal
- Volunteers
- 90 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Pain, Ketorolac
Atomized Intranasal Ketorolac at 30 mg Versus 20 mg for the Treatment of Acute Pain in the Emergency Department
This study aims to compare the analgesic effectiveness and side effects of intranasal ketorolac at 30 mg Versus 20 mg for the Treatment of Acute moderate and severe Pain in the Emergency Department.
- Conditions
- Pain, Ketorolac, Intranasal Drug Administration
- Trial name
- NCT07816302
- Testing
- 20mg intranasal ketorolac, 30mg Intranasal Ketorolac
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Pain Management, Posterior Spinal Fusion
Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery
This study consisted of a randomized controlled trial designed to evaluate a Multimodal Analgesia (MMA) Protocol on patients undergoing Posterior Spinal Fusion.
- Trial name
- NCT05413902
- Testing
- Toradol, Morphine, Orphenadrine
- Where
- Puerto Rico
- Volunteers
- 100 people
- Sponsor
- University of Puerto Rico
Macular Edema, Diabetes Mellitus
A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus
There is a need to find an effective therapy for diabetic patients who develop macular edema after cataract surgery.
- Trial name
- NCT01673191
- Testing
- Dexamethasone intravitreal implant, Steroid plus NSAID eye drop combination therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Retinal Consultants of Arizona
Closed Fracture of Ankle
NSAIDs for Pain After Ankle Fracture Surgery
The purpose of this study is to investigate if it is possible to decrease opioid consumption in patients undergoing ankle fracture surgery by providing scheduled doses of nonsteroidal inflammatory drugs (NSAIDs).
- Trial name
- NCT02281968
- Testing
- Naproxen
- Sponsor
- Northwell Health
Pain, Postoperative, Osteoarthritis, Knee
Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin
Evaluation of the analgesic efficacy of a pre-operative dose of ketorolac and gabapentin in reducing post-operative pain scores in patients undergoing TKA
- Trial name
- NCT07047040
- Testing
- Ketorolac Tromethamine 30 MG/ML Prefilled Syringe, Gabapentin, Empty Medication Capsules
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Knee Injuries
Acute Pain and Inflammation After Surgery
The purpose of this study is 1. to observe acute pain after surgery and measure the natural course of inflammatory mediators 2. study pain relieving effects and local anti-inflammatory effects of systemically administered…
- Trial name
- Knemikro01 (NCT00774540)
- Testing
- 1 Ketorolac intraarticular
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
ACL Repair
The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction
The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical…
- Trial name
- NCT06603051
- Testing
- Cryoneurolysis
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Virtua Health, Inc.
Pain Management
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).
- Trial name
- NCT02276495
- Testing
- ACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Irvine
Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome
Postoperative Pain Management on Uvulopalatopharyngoplasty Patients
This is a randomized controlled study, aimed to investigate the effects of dinalbuphine sebacate (DS) on patients having uvulopalatopharyngoplasty (UPPP). DS is a prodrug of nalbuphine, a mixed agonist-antagonist opioid.
- Conditions
- Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome, Pain, Acute
- Trial name
- NCT05825495
- Testing
- Dinalbuphine sebacate, Routine practice
- Volunteers
- 78 people
- Sponsor
- Li-Jen Hsin
Failed Mechanical Induction
Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block
The aim of this study was to determine whether combining an intraoral injection of a non steroidal anti-inflammatory drug (Ketorolac), in association with conventional inferior alveolar nerve block, would improve the success rate…
- Trial name
- NCT02536430
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahid Mohammadzadeh Akhlaghi
Aortic Dissection, Inflammation
Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection
This multicenter, randomized, double-blind, placebo-controlled trial evaluates the efficacy and safety of ketorolac in 1,346 patients with Stanford Type A aortic dissection, conducted between 2025 and 2028.
- Trial name
- NCT06968806
- Testing
- Ketorolac, 0.9 % saline
- Where
- China
- Volunteers
- 1,346 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Macular Edema, Cystoid Macular Edema
Effectiveness of Periocular Drug Injection in CATaract Surgery
Cystoid macular edema (CME) is a major cause of suboptimal postoperative visual acuity after cataract surgery. Topical steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs) are used to prevent CME.
- Conditions
- Macular Edema, Cystoid Macular Edema, Retinal Disease, Cataract
- Trial name
- EPICAT (NCT05158699)
- Testing
- Bromfenac, Dexamethasone, Triamcinolone Acetonide
- Where
- 10 sites in Austria, Germany and 2 more
- Volunteers
- 628 people
- Sponsor
- Luigi Rondas
Cholelithiasis, Pain, Postoperative
Postoperative Pain Will be Compared in Cholecystectomy Patients: Half Receiving TAP Block and Half Without it.
This study compares the effectiveness of a Transversus Abdominis Plane (TAP) block in reducing post-operative pain for patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07465406
- Testing
- Bupivacaine 0.25%, Standard Post-Operative Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Darul Sehat Hospital
Migraine Headache
Low-dose Propofol for Pediatric Migraine
Propofol, a general anesthetic, has been suggested to be effective for the treatment of migraine headaches in adults when used in subanesthetic doses (lower doses than those used for anesthesia or sedation).
- Trial name
- NCT01604785
- Testing
- Propofol, Standard Treatment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Oregon Health and Science University