Clinical trials: Ketorolac
Pain, Postoperative
Comparison of Outcomes Between Intraosseous Femoral and Tibial Injection in Simultaneous Bilateral Total Knee Arthroplasty Patients
In patients with osteoarthritis of the knee whose pain cannot be relieved by conservative treatment, total knee arthroplasty (TKA) is the operation that increases the quality of life for the patient.
- Trial name
- NCT06243575
- Testing
- Multimodal Intraosseous Femoral Injection, Multimodal Intraosseous Tibial Injection
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Nephrolithiasis
Narcotic-Free Percutaneous Nephrolithotomy
This is a randomized control trial comparing oral ketorolac and opioid medication for the use of post-operative analgesia.
- Trial name
- NCT05924165
- Testing
- 5mg Oxycodone, Q6 PRN, 10mg Ketorolac, Q6 PRN
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cystoid Macular Edema, Postoperative, Diabetes Mellitus
Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients
The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract…
- Trial name
- NCT02646072
- Testing
- Ketorolac tromethamine ophthalmic solution 0.45%
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Infertility, Infertility, Female
Assessing Ketorolac (Toradol) at Oocyte Retrieval
To determine if a nonsteroidal anti-inflammatory drug (NSAID), Ketorolac (Toradol), can improve pain control and decrease narcotic use after undergoing egg retrieval.
- Conditions
- Infertility, Infertility, Female, Oocyte Retrieval, Postoperative Pain
- Trial name
- Alleviate (NCT06026553)
- Testing
- Ketorolac (Toradol)
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Postoperative Pain, Weakness, Muscle
Periarticular Infiltration of Local Anesthetics Versus Pericapsular Nerve Group Block for Total Hip Replacement
This randomized trial is set out to compare the postoperative strength preservation capacity of local infiltration anesthesia (LIA) and pericapsular nerve group (PENG) block after performing a primary total hip arthroplasty…
- Conditions
- Postoperative Pain, Weakness, Muscle, Analgesia, Motor Activity
- Trial name
- NCT05087862
- Testing
- Ultrasound-guided pericapsular nerves group of the hip block, Pericapsular local anesthetic infiltration of the hip
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Bunion
Ketorolac Effects on Post-operative Pain and Bone Healing
This will be a randomized double-blind placebo-controlled clinical trial that will accept all eligible consecutive patients undergoing elective Kalish bunionectomies.
- Trial name
- NCT01133639
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Beth Israel Deaconess Medical Center
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Ureteral Stent Placement, Kidney Stone
NSAIDs Stent Study
This is a pilot study to (1) evaluate the effect of Ketorolac on inflammatory response and its impact on stent related symptoms in patients undergoing stent placement procedure and (2) assess feasibility of recruitment…
- Trial name
- NCT03638999
- Testing
- Ketorolac Trometamol 30Mg/1mL Injection, Normal saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Washington University School of Medicine
Migraine, Chronic Migraine
Eptinezumab as an Adjunct to Standard of Care for Migraine in an Acute Emergency Context
The purpose of the study is to investigate how a medication called eptinezumab (Vyepti) given to patients in the Emergency Department (ED) might help prevent migraines from happening again.
- Trial name
- NCT06428838
- Testing
- Eptinezumab, Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 102 people
- Sponsor
- Dr George Medvedev
Irreversible Pulpitis
Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain
The aim of this study is premedication efficacy of analgesics on post endodontic pain. Sixty-six healthy adult volunteers including criteria, are participating.
- Trial name
- NCT02614118
- Testing
- Ketorolac tromethamine, Acetaminophen
- Where
- Iran
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Opioid Use, Pain, Post Operative
A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery
Opioid addiction in post-operative patients is recognized but not fully understood; therefore, in order to address this growing crisis, it is essential to explore alternative approaches to managing pain and apply them to the…
- Trial name
- NCT05252858
- Testing
- nCAP Signal Relief Patch, Standard of Care
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Jacques E. Chelly
Hyperalgesia, Secondary
Modulation of Remifentanil-induced Postinfusion Hyperalgesia
In addition to alleviate pain there is growing evidence that µ-opioids enhance pain. This problem is known as opioid induced hyperalgesia(OIH).The NMDA receptor is involved in opioid induced hyperalgesia it may be possible to…
- Trial name
- NCT00785863
- Testing
- Remifentanil, Ketorolac and remifentanil, Parecoxib and remifentanil
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Pain, Dental Impaction
A Single-dose Study of Intranasal Ketorolac in the Treatment of Pain Secondary to Dental Impaction Surgery
The purpose of this study is to evaluate the analgesic efficacy of a single intranasal (IN) administration of ketorolac after dental impaction surgery.
- Trial name
- NCT01356225
- Testing
- Ketorolac tromethamine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Egalet Ltd
Laparoscopic Surgery
Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery
The purpose of this study is to determine the analgesic efficacy and safety of N1539 in subjects undergoing abdominal laparoscopic surgery.
- Trial name
- NCT01436032
- Testing
- N1539, Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alkermes, Inc.
Proliferative Diabetic Retinopathy, Macular Edema
Topic Ketorolac Added to Panphotocoagulation in Proliferative Diabetic Retinopathy
The purpose of this study is to determine the efficacy and safety of topic ketorolac in treatment for center point thickness secondary to panphotocoagulation in proliferative diabetic retinopathy.
- Trial name
- NCT00907114
- Testing
- Ketorolac tromethamine, Polivynilic alcohol
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Hospital Juarez de Mexico
Primary Osteoarthritis Requiring Total Hip Replacement
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)
Postoperative pain following total hip arthroplasty (THA) (1) is often considered moderate to severe and can therefore influence the postoperative course of event and result in delayed postoperative mobilization and prolonged…
- Trial name
- HÖFTPLASTIK (NCT01281891)
- Testing
- LIA, I/T morphine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Örebro County
Morbid Obesity, PCA
Dual-chamber Patient-controlled Analgesia for Postoperative Recovery
Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV.
- Conditions
- Morbid Obesity, PCA, Analgesia, PONV
- Trial name
- NCT07051109
- Testing
- multimodal analgesia via dual-chamber PCA, single regimen (only fentanyl)
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Bundang Hospital
Urologic Diseases
Pain Management in Outpatient Urologic Procedures
Goal of this study is to evaluate how pain is controlled after outpatient urologic surgeries. Patients will receive either opioid pain medication or non-opioid medication for pain control.
- Trial name
- NCT03393364
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Low Back Pain, Mechanical
Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department
The randomized controlled study aims was to investigate the pain control of Battle Field Acupuncture as Primary or Adjunctive Treatment in Back Pain (Acute Musculoskeletal pain) in the (acute pain setting) Emergency Department vs…
- Trial name
- NCT03996564
- Testing
- Battlefield Acupuncture, Acetaminophen, Diclofenac
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center