Clinical trials: Ketorolac
Post Operative Pain, Urolithiasis
Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease
Objective: To improve quality-of-life and health care delivery to patients receiving ureteral stents. Specific Aims: Evaluate the feasibility, practicality, and qualitative outcomes of utilizing intra-nasal ketorolac in patients…
- Conditions
- Post Operative Pain, Urolithiasis, Ureter Calculi, Stent Complication
- Trial name
- NCT06158620
- Testing
- intra-nasal ketorolac, oral diclofenac
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Tonsillitis, Post-operative Nausea and Vomiting (PONV)
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham.
- Conditions
- Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction
- Trial name
- NCT06326983
- Testing
- Dexmedetomidine, Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Children's Hospital
Mastectomy, Modified Radical
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT07257874
- Testing
- bupivacaine 0.5% injection, Ketorolac 30 mg IV
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Orthopaedic Trauma, Chronic Opioid Use
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
The goal of this randomized clinical trial is to learn if the use of a low-dose nonsteroidal anti-inflammatory drug (NSAID), ketorolac, reduces the rate of chronic opioid use in orthopaedic trauma patients.
- Trial name
- NCT06201676
- Testing
- Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Massachusetts General Hospital
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Tibial Plateau Fractures
Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures
The investigators goal of the proposed research study is to determine the effectiveness of periarticular multimodal analgesia in the setting of tibial plateau fractures.
- Trial name
- NCT05037812
- Testing
- Saline injection, Multimodal injections
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Utah
Pain, Postoperative
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
This clinical study is a randomized, double-blind, double-dummy, parallel group, multi-center, active and placebo-controlled trial evaluating the analgesic efficacy and safety of NTM-001 in subjects with moderately severe…
- Trial name
- NCT05324358
- Testing
- Ketorolac Tromethamine, Morphine Sulfate
- Where
- 10 sites in United States
- Volunteers
- 341 people
- Sponsor
- Neumentum, Inc.
Bone Metastases, Lymphoma
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing…
- Conditions
- Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use
- Trial name
- NCT03823534
- Testing
- Ketorolac, Normal saline, Acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Postoperative Pain
The Effect of Anti-inflammatory Cryoagent on the Level of Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis and Apical Periodontitis.
The aim of this study is comparative between: 1. Intra-radicular cryotherapy using cold anti-inflammatory {ketorolac tromethamine at 2-5C}. 2.
- Trial name
- NCT06584188
- Testing
- anti-inflammatory ketorolac tromethamine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Extracorporeal Shockwave Lithotripsy
Intravenous Acetaminophen and Ketorolac for Pain Management During Extracorporeal Shockwave Lithotripsy
The goal of this clinical trial is to learn if a non-opioid pain medicine regimen works as well as or better than a standard opioid-based regimen to manage pain during extracorporeal shockwave lithotripsy (ESWL) in adults.
- Trial name
- NCT07368738
- Testing
- IV midazolam, IV fentanyl, IV acetaminophen
- Where
- Canada
- Volunteers
- 266 people
- Sponsor
- Horizon Health Network
Hysterectomy, Gynecologic Surgical Procedures
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally…
- Conditions
- Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
- Trial name
- ON-Q (NCT04130464)
- Testing
- Ropivacaine Infusion from ON-Q Pump, Ropivacaine + Ketorolac Infusion from ON-Q Pump, Normal Saline Infusion from ON-Q Pump
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ying Liu
DeQuervain Tendinopathy
Betamethasone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis
The purpose of this study is to determine if corticosteroid injection modifies the natural course of de Quervain tendinopathy compared to a toradol injection.
- Trial name
- NCT02604537
- Testing
- betamethasone, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Anterior Cruciate Ligament Injury
Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of anterior cruciate ligament reconstruction: a treatment…
- Trial name
- NCT03818932
- Testing
- Celecoxib, Hydrocodone-Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Arthritis Knee, Pain
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and other analgesics.
- Conditions
- Arthritis Knee, Pain, Arthroplasty Complications
- Trial name
- NCT06112548
- Testing
- primary unilateral TKA, Bupivacain, ketorolac
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Post-ERCP Acute Pancreatitis
Rectal Indomethacin vs Intravenous Ketorolac
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential procedure that can be complicated by post-ERCP pancreatitis (PEP). Indomethacin and ketorolac are two medications used to prevent PEP.
- Trial name
- NCT05664074
- Testing
- Rectal indomethacin, IV ketorolac
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- David Vitale MD
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Post Cesarean Pain
Dosing of Ketorolac Impacts Post-cesarean paiN manaGemenet (KING)
This is a randomized controlled single blinded trial to compare the morphine milligram equivalents (MME) use in the first 24 hours postoperatively after cesarean section in patients receiving a single dose of 30 mg intravenous…
- Trial name
- KING (NCT05248984)
- Testing
- Ketorolac 30 Mg, Ketorolac 60 Mg
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Ohio State University
Thumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis.
- Trial name
- NCT05992883
- Testing
- Ketorolac, Triamcinolone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Cleft Lip and Palate
Ketorolac in Palatoplasty
The purpose of this study is to see if the addition of IV Ketorolac to usual care multi-modal pain therapy compared to usual care will improve oral intake post-operatively
- Trial name
- NCT04771156
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University