Clinical trials: Ketorolac
Liver Diseases, Hepatocellular Cancer
A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation
Living donor liver transplantation (LDLT), involves complex systems and processes of care that are particularly vulnerable to medical errors and preventable complications.
- Conditions
- Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
- Trial name
- NCT02073435
- Testing
- Donor pain management
- Where
- 4 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cataract
Nevanac 3-Month Safety Study With QID Dosing
The purpose of this study is to determine the safety of Nevanac 0.1% compared to Acular LS 0.4% and Vehicle in patients treated before cataract surgery and for approximately 90 days following surgery.
- Trial name
- NCT00332774
- Testing
- Nepafenac ophthalmic solution 0.1%, Ketorolac Tromethamine ophthalmic solution 0.4%, Nepafenac ophthalmic suspension vehicle
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Alcon Research
Acute Pain
Dosing of Ketorolac in the Emergency Department
The optimal dose of ketorolac in the Emergency Department setting is no clear. We will compare 3 doses to determine the optimal dose.
- Trial name
- NCT03464461
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- University of Missouri-Columbia
Pregnancy Related, Narcotic Use
Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section
This randomized controlled trial will compare two different approaches to patient recovery after cesarean section: the current standard of care versus an alternate management protocol.
- Trial name
- NCT03330119
- Testing
- Alternate Management, Control
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Brest, Norman A., M.D.
Postoperative Pain
ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management
After surgery it is normal to experience some pain at the site of operation. In order to reduce the pain, medication such as Morphine is injected into a vein using a Patient Controlled Analgesia (PCA) pump that is kept at bed…
- Trial name
- NCT00638508
- Testing
- Ketorolac, Ketorolac and Ropivacaine
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Maimonides Medical Center
Cystoid Macular Edema, Cataract
Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification
To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular edema (CME) after small-incision cataract extraction.
- Trial name
- NCT02084576
- Testing
- Nepafenac, Ketorolac
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Retinopathy of Prematurity
Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)
Phase 2, open-label, randomized, multi-center studies in infants and premature infants are necessary to determine treatment and preventative strategies for ROP.
- Trial name
- SPIPROP (NCT02344225)
- Testing
- Caffeine citrate, Ibuprofen, Ketorolac
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
ACL Surgery, Pain Management
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder.
- Trial name
- NCT07158476
- Testing
- Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- St. Louis University
Postoperative Pain, Knee Replacement Arthroplasty
Management of Postoperative Pain After Total Knee Replacement.
The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.
- Trial name
- NCT01163214
- Testing
- Nerve Block, Periarticular Injection
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mark J. Spangehl, M.D.
Postoperative Pain, Total Knee Arthroplasty
Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty
This study is a randomized-clinical-trial on 146 patients candidate for total knee arthroplasty (TKA) who were randomly allocated to three treatment groups, including 1) a cocktail consisting of bupivacaine, morphine…
- Trial name
- NCT05324995
- Testing
- Multimodal Drug, epinephrine, celecoxib
- Where
- Iran
- Volunteers
- 146 people
- Sponsor
- Isfahan University of Medical Sciences
Keratoconus, Ectasia
Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas (2)
To evaluate the efficacy of ultraviolet-A (UVA)-induced cross-linking of corneal collagen (CXL) as a method to increase the biomechanical and biochemical stability of the cornea by inducing additional cross-links within or…
- Conditions
- Keratoconus, Ectasia, Degeneration
- Trial name
- NCT01097447
- Where
- 5 sites in United States
- Volunteers
- 2,619 people
- Sponsor
- Cxlusa
Postoperative Pain
A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty
The purpose of this study is to determine wether ketorolac is effective in the treatment of postoperative pain after total knee arthroplasty
- Trial name
- NCT00868348
- Testing
- Ketorolac, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Periarticular Block, Osteoarthritis (OA)
Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA
Prospective Cohort of patients who are scheduled for a Robot Assisted Total Knee Arthroplasty (RATKA). A prospective survey of patient reported outcome measures (Numeric Rating Scale) will be obtained postoperatively of 72 hours…
- Conditions
- Periarticular Block, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Pain After Surgery
- Trial name
- NCT07430085
- Testing
- bupivacaine-meloxicam (extended release), Bupivacaine, Ketorolac
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Wound and Injuries, Pain
Comparison of Pain Reduction in Painful Chronic Wounds With and Without Fat Grafting
Chronic wounds, such as those caused by diabetes, burns, or poor blood circulation, often heal slowly and can cause significant pain, affecting daily life and quality of life.
- Trial name
- PAINFAT (NCT07480447)
- Testing
- Autologous Fat Grafting, Standard Wound Care
- Volunteers
- 62 people
- Sponsor
- King Edward Medical University
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Subacromial Impingement Syndrome, Subacromial Bursitis
Subacromial Injection With Corticosteroid Versus Nonsteroidal Anti-inflammatory Drugs (NSAID) in Shoulder Impingement Syndrome
Injection with corticosteroid is one of the most common non-operative interventions in the treatment of subacromial impingement; however, its use is limited by its potential side effects (e.g.
- Trial name
- NSAID (NCT01449448)
- Testing
- Ketorolac, Triamcinolone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Acute Cholecystitis, Gangrenous Cholecystitis
Enhanced Recovery in Laparoscopic Cholecystectomy
The study assesses the impact of the modified enhanced recovery protocol on the results of surgical treatment of patients with acute cholecystitis.
- Trial name
- ERLAC (NCT03754751)
- Testing
- Laparoscopic cholecystectomy with the implementation of modified ERAS program, Laparoscopic cholecystectomy with standard perioperative treatment
- Where
- Russia
- Volunteers
- 189 people
- Sponsor
- Pirogov Russian National Research Medical University
Mechanical Ventilation, Pediatric Acute Respiratory Failure
Optimizing Pain Treatment in Children On Mechanical Ventilation
In this clinical trial, investigators want to learn more about using non-opioid pain medications for children with acute respiratory failure.
- Conditions
- Mechanical Ventilation, Pediatric Acute Respiratory Failure, Analgesics, Opioid, Sedation and Analgesia
- Trial name
- OPTICOM (NCT06994442)
- Testing
- Acetaminophen, Ketorolac
- Where
- 16 sites in United States
- Volunteers
- 644 people
- Sponsor
- Weill Medical College of Cornell University
Emergence Delirium
Ketamine Versus Dexmedetomidine for Prevention of Postoperative Delirium
Delirium is a common postoperative complication in the elderly, often caused by multiple factors. It is defined as an acute neuropsychiatric disorder characterized by fluctuating disturbances in attention, awareness, and…
- Trial name
- NCT05341154
- Testing
- Ketamine Hcl 50Mg/Ml Inj
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Huda Fahmy Mahmoud, PhD
Postoperative Nausea and Vomiting, Colorectal Neoplasms
Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery
Background: PONV is one of the prevalent discomforts in the early phase of recovery after surgery. Evidence suggests that the stimulation of the P6 acupuncture point can reduce the occurrence of PONV.
- Trial name
- AcuPONV (NCT02509143)
- Testing
- High-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Yangsan Hospital