Clinical trials: Lidocaine
Dexamethasone Efficacy as an Adjuvant in Supraclavicular Block
Dexamethasone as an Adjuvant in Supraclavicular Block
The use of dexamethasone perineurally along with local anesthetic has been shown to improve the duration of analgesia .
- Trial name
- NCT04345588
- Testing
- Dexamethasone injection
- Volunteers
- 60 people
- Sponsor
- Assiut University
Vulvar Cancers, Vulva Neoplasm
Needlefree Lidocaine Application for Vulvar Biopsies
The goal of this study is to compare pain during a vulvar biopsy using either the needle-free J-Tip device or the standard lidocaine shot.
- Conditions
- Vulvar Cancers, Vulva Neoplasm, Vulvar Dysplasia
- Trial name
- NCT07793552
- Testing
- J-Tip, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Lidocaine, Analgesia
Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection.
- Conditions
- Lidocaine, Analgesia, Pain, Postoperative, Thoracic Surgery
- Trial name
- NCT05901389
- Testing
- Lidocaine, Sufentanil
- Where
- China
- Volunteers
- 451 people
- Sponsor
- Qilu Hospital of Shandong University
Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds
Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds
A multicenter, active-controlled, randomized, evaluator and subject blinded, split-face, comparative, non-inferiority, Medical device Clinical trial.
- Trial name
- NCT03170050
- Testing
- YYD701-2, Restylane Perlane Lidocaine
- Where
- 2 sites in South Korea
- Volunteers
- 107 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Single-level Lumbar Arthrodesis
Intravenous Lidocaine Versus Erector Spinae Plane Block After Lumbar Arthrodesis (LIBERA)
The hypothesis of this study is that intraoperative intravenous lidocaine infusion provides postoperative analgesia and opioid-sparing effects that are at least equivalent to those achieved with a bilateral erector spinae plane…
- Trial name
- LIBERA (NCT07895368)
- Testing
- Single-level posterior lumbar arthrodesis
- Where
- France
- Volunteers
- 90 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Epistaxis
Topical 15% Trichloroacetic Acid Versus Silver Nitrate Cauterization in the Management of Idiopathic Childhood Epistaxis: A Prospective Double-Blinded, Randomized Clinical Trial
the invistigators aim to explore the efficacy of trichloroacetic acid as a chemical cauterization agent and compare it with that of silver nitrate in the treatment of idiopathic epistaxis in children.
- Trial name
- Epistaxis (NCT06836791)
- Testing
- chemical cautrizating agents to stop epistaxis, Silver Nitrate, Trichloroacetic Acid Topical
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Youssef Zaki
Chronic Migraine, Headache
Mesotherapy in the Treatment of Chronic Migraine
Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin.
- Trial name
- NCT06118190
- Testing
- Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Airway Complication of Anaesthesia
For A More Comfortable Bronchoscopy: Is Spray Catheter The Answer?
Bronchoscopy is a commonly performed procedure for inpatients to visualize the airways when indicated. It is routinely done for both diagnostic (to lavage and biopsy the respiratory tract) and therapeutic purposes (to relief an…
- Trial name
- NCT02372760
- Testing
- BA by spray catheter (Olympus PW-205V), BA classic anesthesia, Anesthesia
- Where
- United States
- Sponsor
- University of Florida
Dermal Filler, Volume Deficiency of the Midface
An Interventional Study to Evaluate the Safety and Performance of Crosslinked Hyaluronic Acid Hydrogel
The aim of this interventional, pre-market, double- blinded, controlled, two stages study is to evaluate the performance and safety of Crosslinked Hyaluronic Acid (CLHA) Hydrogel (with and without Lidocaine) for the Treatment of…
- Trial name
- NCT05853224
- Testing
- Crosslinked Hyaluronic Acid (CLHA) Hydrogel with and without Lidocaine
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Biopolimeri Srl
Gastroesophageal Reflux Disease
Stellate Ganglion Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06319521
- Testing
- Rehabilitation therapy, Stellate ganglion block, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Post Herpetic Neuralgia
A Study With Lidocaine 5% Medicated Plaster in Patients Suffering From Postherpetic Neuralgia
This study was performed to evaluate the local and systemic safety profile and the analgesic efficacy of long-term treatment with lidocaine 5% medicated plaster (Lido-Patch).
- Trial name
- NCT03765697
- Testing
- Lidocaine 5% medicated plaster
- Volunteers
- 259 people
- Sponsor
- Grünenthal GmbH
Capsaicin, Ultaviolet B Light Burn
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
The aim of this project is to study the role of transient receptor potential (TRP-) channel V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal Ultraviolet-B damage.
- Conditions
- Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain, Lidocaine
- Trial name
- NCT03587220
- Testing
- Capsaicin Topical, Ultraviolet-B (UVB) irradiation, Histamine 1%
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Procedural Pain
Comparison of Virtual Reality, EMLA Cream, and Standard Care for Pain During Blood Draws in Children
This randomized controlled trial evaluates methods to reduce pain during venipuncture in children aged 3 to 15 years. The study compares three approaches: virtual reality distraction using a VR headset, topical anesthesia with…
- Trial name
- NCT07763132
- Testing
- Virtual Reality Distraction, Lidocaine-Prilocaine Cream
- Where
- Czechia
- Volunteers
- 450 people
- Sponsor
- Marie Lulková
Colo-rectal Cancer
Comparison of Ultrasound-guided Erector Spinae Plane Block and Transmuscular Quadratus Lumborum Block
The objective of this study is to compare the postoperative analgesic effect of bupivacaine injection via ultrasound-guided erector spinae block versus transmuscular quadratus lumborum block in patients undergoing abdominal…
- Trial name
- NCT05709899
- Testing
- nerve blocks
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain
Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Burn pain is known to be one the most severe forms of acute pain often requiring large amounts of narcotics in addition to other adjuvants.
- Trial name
- LidocaineBurn (NCT02229578)
- Testing
- Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Lip Augmentation
Clinical Investigation of YVOIRE Y-Solution 360 for Lip Augmentation in China
To evaluate the effectiveness and safety of the investigational medical device, injected into the lips.
- Trial name
- NCT05314504
- Testing
- YVOIRE Y-Solution 360
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- LG Chem
Hysteroscopy
Comparison Between the Intrauterine Lidocaine and Warm Saline Distention Medium for Pain Relief During Office Hysteroscopy
Procedure: The procedure was done in the lithotomy position during the postmenstrual period. We used a 30° angle 2.9 mm rigid hysteroscopy with 3.8 mm diagnostic sheath [TEKNO®, LIGHT XA 180, Germany].
- Trial name
- NCT06946121
- Testing
- Lignocaine, Saline
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pain, Satisfaction, Patient
Lidocaine Spray vs Viscous Lidocaine Solution Plus Lidocaine Spray in Patients Undergoing Non-Sedated EGD
This study aimed to compare the efficacy of lidocaine spray (S) alone versus lidocaine spray combined with lidocaine viscous solution (S+V) in facilitating pharyngeal observation during Non-sedating upper gastrointestinal…
- Trial name
- NCT06185933
- Testing
- Lidocaine Spray, Lidocaine Viscous+Lidocane spray
- Where
- Thailand
- Volunteers
- 250 people
- Sponsor
- Sawanpracharak hospital
Carpal Tunnel Syndrome (CTS)
Does it Matter the Volume of Injectate on the Outcome of Ultrasound-guided Perineural Injection for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is an entrapment neuropathy affecting the median nerve with a lifetime prevalence of about 8% in the adult population.
- Trial name
- NCT07283874
- Testing
- Dextrose 5%, Triamcinolone Acetonide (Aristocort® C), Lidocaine 2 %
- Volunteers
- 35 people
- Sponsor
- Assiut University
Postoperative Pulmonary Complications (PPCs)
Intraoperative Nebulization of Lidocaine and Postoperative Pulmonary Complications
There is high incidence of postoperative pulmonary complications (PPCs) in patients undergoing major abdominal surgeries.PPCs significantly prolongs the hospital stay of patients, increases their economic burden, and raises the…
- Trial name
- NCT07000760
- Testing
- Nebulization of lidocaine, Nebulization of normal saline
- Where
- 2 sites in China
- Volunteers
- 270 people
- Sponsor
- Jun Zhang