Clinical trials: Manual therapy
Cerebral Palsy, Spastic, Achilles Tendon Contracture
Myofascial Release Plus Physiotherapy for Children With Cerebral Palsy Post Achilles Tendon Surgery in Gaza (MFR-CP25)
"This study aims to evaluate the effectiveness of adding Myofascial Release (MFR) technique to a conventional physiotherapy program for children with cerebral palsy after Achilles tendon surgery.
- Trial name
- MFR-CP25 (NCT07148856)
- Testing
- Conventional Physiotherapy, Myofascial Release Technique
- Where
- Palestinian Territories
- Volunteers
- 40 people
- Sponsor
- Ismail K. Al-Qudra
Family Members
Improving Family Engagement in Coordinated Specialty Care for First Episode Psychosis
Investigators aim to develop and evaluate a culturally informed family motivational engagement strategy (FAMES) and implementation toolkit for coordinated specialty care (CSC) programs for first episode psychosis.
- Trial name
- NCT04188366
- Testing
- FAMES, Treatment-as-Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington State University
Anger
Effectiveness of Anger Management Treatment in Reducing Anger-Related Behaviors in Female Juvenile Offenders
This study will evaluate the effectiveness of an anger management treatment program, Juvenile Justice Anger Management for Girls, in reducing anger-related behaviors displayed by girls in the juvenile justice system.
- Trial name
- NCT00720486
- Testing
- Juvenile Justice Anger Management (JJAM) for Girls, Treatment as usual
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- naomi goldstein
Severe Combined Immunodeficiency Disease, X-linked
Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
SCID-X1 is a genetic disorder of blood cells caused by DNA changes in a gene that is required for the normal development of the human immune system.
- Trial name
- LVXSCID-ND (NCT01512888)
- Testing
- CL20-i4-EF1α-hγc-OPT, Busulfan, CliniMacs
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- St. Jude Children's Research Hospital
Lung Non-Small Cell Carcinoma, Stage I Colorectal Cancer AJCC v8
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer
This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors.
- Conditions
- Lung Non-Small Cell Carcinoma, Stage I Colorectal Cancer AJCC v8, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8
- Trial name
- NCT04428905
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Survivorship Care Plan
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- City of Hope Medical Center
Ventilators, Mechanical, Intensive Care Units
Postoperative INTELLiVENT-ASV Ventilation
The aim of this study is to investigate whether postoperative ventilation with INTELLiVENT-ASV(adaptive support ventilation) in high risk patients, after cardiothoracic surgery, is as effective, more user-friendly and as safe as…
- Conditions
- Ventilators, Mechanical, Intensive Care Units, Postoperative Care
- Trial name
- POSITiVE (NCT03180203)
- Testing
- INTELLiVENT-ASV, Conventional modes
- Where
- Netherlands
- Volunteers
- 220 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Attention Deficit Hyperactivity Disorder (ADHD)
Effects of Structured Skills Training Group in Treatment of ADHD in Adults
This study aims to examine if structured skills training group therapy for ADHD in adults has beneficial effects superior to 'treatment as usual' including medication in a controlled outpatient setting on clinically relevant…
- Trial name
- NCT02685254
- Testing
- Structural skills training group, Treatment as usual
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- University of Oslo
Pulmonary Atelectasis
Ventilator Hyperinflation and Manual Rib Cage Compression
This is a randomized crossover trial to evaluate the effects of thoracic compression applied alone or in association with hyperinflation maneuver with the ventilator.
- Trial name
- NCT03630484
- Testing
- Expiratory Rib Cage Compression, Compression + Ventilator Hyperinflation
- Volunteers
- 30 people
- Sponsor
- Brazilian Institute of Higher Education of Censa
Vagus Nerve Stimulation
Multi-device Testing for Autonomic Nervous System Stimulation
The Vagus nerve (VN) serve as an "unconscious inner brain" that integrates messages from the body and provides metabolic homeostatic regulation to various organs.In this study the investigators want to compare different ways to…
- Trial name
- NCT04341649
- Testing
- Manual Head Massage, BREO Helmet Massager, Low Laser Therapy (LLT)
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Prostate Cancer
A Couple Support Intervention for Prostate Cancer
Even with careful prostate surgery, men find it difficult to have an erection. Our previous research shows that couples are not often supported to cope with the effects of surgery on their sexual relationships.
- Trial name
- NCT01842438
- Testing
- Behavioral: psychosexual intervention
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- University of Stirling
Obesity
Comparison of Two Surgical Techniques for Treatment of Type III Obesity (BMI 40-50 kg/m2): Single Anastomosis Duodenoileal Bypass With Sleeve Gastrectomy and Roux-en-Y Gastric Bypass.
Roux-en-Y gastric bypass (RY-GBP) is one of the surgical techniques most widely used for the treatment of obesity. Long series of operated patients published in the literature have demonstrated its safety and efficacy.
- Trial name
- BYPSADIS (NCT06789965)
- Testing
- SADI-S, RY-GBP
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Hospital Clinic of Barcelona
Anterior Cruciate Ligament Reconstruction Rehabilitation
ACL Reconstruction Rehabilitation With Exercise and Psychological Support
The purpose of this study is to examine ACLR Rehabilitation with Exercise and Psychological Support (REPS), comparing two approaches for providing psychological support along with exercise during ACL reconstruction…
- Trial name
- ACLR-REPS (NCT06991192)
- Testing
- Rehabilitation with Exercise and Psychological Support (REPS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- HealthPartners Institute
Knee Arthropathy
A Pilot Feasibility Study Comparing Smartphone Home-based Rehabilitation Program Against the Usual Hospital and Outpatient Physiotherapy Care on Clinical and Cost Effectiveness for Total Knee Replacement Patients
Knee osteoarthritis (OA) is a common, chronic, and costly condition whilst total knee replacement (TKR) is a common orthopaedic surgical intervention.
- Trial name
- NCT06248034
- Testing
- Smartphone application with tele-monitoring rehabilitation, Hospital-based rehabilitation program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Solar Purpura
Microneedling for Dermatoporosis
We hypothesize that a series of treatments with a microneedling protocol will lead to increased dermal thickness as measured by biopsy, ultrasound, and skin calipometry; an improvement in dermatology-related quality of life; and…
- Trial name
- NCT04912219
- Testing
- Microneedling
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Gastrointestinal System Disease, Functional Bloating
Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention
Abdominal bloating and distension (ABD) are the most commonly gastrointestinal symptoms reported by patients with various functional gut disorders such as functional dyspepsia, irritable bowel syndrome and it is frequently…
- Conditions
- Gastrointestinal System Disease, Functional Bloating, Distension; Bowel, Gastrointestinal Motility Disorder
- Trial name
- NCT06347367
- Testing
- Group 1 (exercise and self-manual approaches targeting only the diaphragm muscles), Group 2 (exercise and self-manual approaches targeting both diaphragm and core muscles)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Attention Deficit Disorder With Hyperactivity
Cognitive Behavioral Therapy for Treatment of Adult Attention Deficit Hyperactivity Disorder
This study will determine the efficacy of cognitive behavioral therapy in treating adults with attention deficit hyperactivity disorder.
- Trial name
- NCT00118911
- Testing
- Cognitive behavioral therapy (CBT), Relaxation techniques and education about ADHD
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Massachusetts General Hospital
Ventilator Associated Pneumonia ( VAP), Intensive Care (ICU)
Integrated vs Manual Endotracheal Tube Cuff Pressure Monitoring and Ventilator-Associated Pneumonia
Ventilator-associated pneumonia (VAP) is a frequent complication in mechanically ventilated patients in intensive care unit (ICU).
- Trial name
- ICPM-VAP (NCT07423208)
- Testing
- Continous measurement of cuff pressure in endotracheal tube, Intermittent manual cuff pressure monitoring with manometer.
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Type 2 Diabetes Mellitus
A Psychological-behavioral Intervention to Increase Activity in Type 2 Diabetes
The focus of this study is to examine the feasibility, acceptability, and impact of a customized, combined positive psychology and motivational interviewing (PP-MI) health behavior intervention in a group of patients with type 2…
- Trial name
- BEHOLD-16 (NCT03164538)
- Testing
- Positive Psychology + Motivational Interviewing, Diabetes Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizotypal Disorder
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
The OPUS YOUNG (OY) study investigates the efficacy of early intervention service versus treatment as usual (TAU) for adolescents aged 12-17 years with a first-episode psychosis.
- Conditions
- Schizophrenia, Schizotypal Disorder, Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
- Trial name
- OPUS-YOUNG (NCT04916626)
- Testing
- OPUS YOUNG, Treatment as Usual
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Pain, Dysmenorrhea Primary
The Effect of Acupressure on Pain, Menstrual Symptoms, and General Comfort in Adolescents With Primary Dysmenorrhea
In this study, it is planned to determine the effect of acupressure applied to adolescents with primary dysmenorrhea on pain, menstrual symptoms and general comfort.
- Conditions
- Pain, Dysmenorrhea Primary, Signs and Symptoms
- Trial name
- NCT05408611
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Mersin University
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