Clinical trials: Manual therapy
Complex Post-Traumatic Stress Disorder (CPTSD)
RECONNECT - Treatments for Complex PTSD
Complex PTSD (CPTSD) is a new diagnosis for which no established gold-standard treatment(s) yet exists. In this trial, three psychotherapies, Prolonged Exposure (PE), Eye Movement Desensitization and Reprocessing (EMDR), and…
- Trial name
- NCT07863089
- Testing
- Prolonged Exposure, EMDR, ESTAIR
- Volunteers
- 225 people
- Sponsor
- University of Copenhagen
Ankle Fracture, Calcaneus Fracture
Manual Therapy After Ankle/Hindfoot Fractures
The aim of this randomized controlled trial is to assess if manual therapy improves mobility, gait, and balance more than a control group for patients who have undergone open reduction internal fixation (ORIF) after an…
- Conditions
- Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
- Trial name
- NCT02609347
- Testing
- Manual Therapy Group, Control Group
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Intermountain Health Care, Inc.
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Insomnia Disorder
Tele-Self CBTI Trial
Insomnia is one of the most common complaints among service-members and Veterans of recent military conflicts. Insomnia has been shown to play a causal role in mental health, hypertension, obesity, and other health conditions…
- Trial name
- Tele-Self CBTI (NCT03727438)
- Testing
- Tele-Self CBTI, Health Education Control
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- VA Office of Research and Development
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Cannabis Use Disorder
Vivitrol Treatment for Cannabis Use Disorder
The purpose of this study is to investigate the safety and effectiveness of 12 weeks treatment with an extended-release injectable form of naltrexone (Vivitrol) combined with a psychological intervention in 10 treatment-seeking…
- Trial name
- NCT04139668
- Testing
- Naltrexone 380 MG [Vivitrol], Motivational Enhancement Therapy and Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Centre for Addiction and Mental Health
Intermittent Fasting, Metabolic Dysfunction-Associated Fatty Liver Disease
Intermittent Fasting and Metabolic Dysfunction Associated Fatty Liver Disease
Previous studies have investigated the effect of different dietary patterns on metabolic dysfunction-associated fatty liver disease (MAFLD), for which lifestyle modification remains the primary treatment.
- Trial name
- NCT06664684
- Testing
- Energy-restricted dietary intervention, Energy + time-restricted dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Spastic Paraplegia
Comparison Between Palpatory and Ultrasound-guided Methods for Botulinum Toxin Administration in Spastic Paraplegia
Spasticity in spastic paraplegia is a major cause of chronic pain and functional limitation. Although botulinum toxin type A (BoNT-A) reduces muscle tone, studies like the SPASTOX trial have shown limited functional improvement…
- Trial name
- NCT07803276
- Testing
- AbobotulinumtoxinA - Ultrasound-Guided Technique, AbobotulinumtoxinA - Conventional Technique
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal Fluminense
Anxiety Symptoms, Depressive Symptoms
Triple Aim Psychotherapy: Aimed at Improving Patient Experience, Population Health, and Cost
Community mental health programs in publically-funded jurisdictions such as Canada often have limited budgets in order to provide services, which can result in inadequate access to effective treatment for patients.
- Trial name
- TAP (NCT03659591)
- Testing
- Cognitive Behaviour Therapy, Adaptive Psychological Training
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Joseph Brant Hospital
Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock
Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial
Background: China's healthcare system for children faces significant challenges, particularly due to the limited pediatric service capacity of primary healthcare institutions.
- Conditions
- Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock, Hand-foot-and-mouth Disease, Acute Appendicitis
- Trial name
- NCT06699433
- Testing
- Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos
- Where
- 3 sites in China
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Southern Medical University, China
Femoroacetabular Impingement
A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial
The purpose of this study is to compare the outcomes for patients that receive two different treatments used for FAI (Femoroacetabular Impingement).
- Trial name
- NCT01993615
- Testing
- Arthroscopic Surgery, Physical Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Madigan Army Medical Center
Opioid Use Disorder
Adaptive Decision Support for Addiction Treatment Master
This study refines and optimizes the EMBED* clinical decision support (CDS; see NCT03658642) to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with…
- Trial name
- ADAPT (NCT06799117)
- Testing
- EMBED CDS, Nurse prompt to complete COWS, Provider Prompt
- Where
- 3 sites in United States
- Volunteers
- 1,912 people
- Sponsor
- Yale University
Caffeine Dependence, Anxiety
Remote Guided Caffeine Reduction
The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use.
- Conditions
- Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction
- Trial name
- NCT04560595
- Testing
- Caffeine Reduction Manual
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Use Disorder
Comparing Smoking Treatment Programs for Lighter Smokers - 1
The purpose of this study was to compare two different types of Food and Drug Administration (FDA) approved smoking cessation medications (nicotine patch or bupropion) used in conjunction with two levels of counseling.
- Trial name
- NCT00086411
- Testing
- nicotine transdermal system, bupropion, Medication Management
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Risk Behavior, Medication Adherence
Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
This study will test whether 3H+ (Holistic Health for HIV) is comparable to the original HHRP+ (Holistic Health Recovery Program) in reducing HIV risk behaviors and improving ART (Antiretroviral Therapy) adherence in a randomized…
- Conditions
- Risk Behavior, Medication Adherence, HIV
- Trial name
- NCT01741311
- Testing
- 3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Connecticut
Lumbar Disc Herniation With Radiculopathy
Manual Therapy Combined With Functional Magnetic Stimulation for Lumbar Radiculopathy
This randomized clinical trial will evaluate whether adding Functional Magnetic Stimulation (FMS) to manual therapy (neurodynamic mobilization) improves clinical outcomes in adults with lumbar radiculopathy caused by lumbar disc…
- Trial name
- NCT07234071
- Testing
- Combined manual therapy and Functional Magnetic Stimulation, Manual Therapy without Functional Magnetic Stimulation
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- International Hellenic University
Atelectasis, Intensive Care Unit
Effect of Thoracic Block Technique on Atelectasis in Children on Mechanical Ventilation
Statement of the problem: Does the thoracic block technique has effect on atelectasis in Children on Mechanical Ventilation? Null hypothesis: there is effect of thoracic block technique on atelectasis in children on Mechanical…
- Conditions
- Atelectasis, Intensive Care Unit, Children
- Trial name
- NCT05480202
- Testing
- Thoracic block technique, Designed chest physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Healthy
REMINDer - A Digital Environmental Enrichment Intervention
The primary goal of this pilot study is to assess the feasibility and effectiveness for improving overall mental and physical well-being of a multimodal intervention program in older adults carried out in a digital telehealth…
- Trial name
- REMINDer (NCT06530277)
- Testing
- REMINDer (A digital environmental enrichment intervention)
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Ozone-therapy (O3), Periodontitis
Ozone-therapy in Non-surgical Periodontal Therapy
Non-surgical periodontal therapy is a widely adopted procedure for the treatment of periodontitis, particularly in its moderate to severe stages.
- Conditions
- Ozone-therapy (O3), Periodontitis, Antimicrobial Ozone Therapy
- Trial name
- PD-OZONE (NCT07202312)
- Testing
- Ozone-therapy after non-surgical therapy
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Brain Concussion, Dizziness
Effectiveness of Early Physical Therapy Intervention for Patients With Dizziness After a Sports-Related Concussion
Therefore, the purpose of this pilot study is to determine the feasibility of conducting a randomized clinical trial (RCT) on physical therapist treatment for dizziness after sports-related concussion.
- Trial name
- NCT02299128
- Testing
- Physical Therapy Treatment
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Walsh University
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