Clinical trials: Methylphenidate, completed
Attention Deficit Disorder With Hyperactivity
Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.
- Trial name
- NCT00031395
- Testing
- clonidine, methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Cincinnati
Attention Deficit Hyperactivity Disorder
Brain Dopamine Function in Adults With ADHD
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and…
- Trial name
- Brookhaven (NCT00580814)
- Testing
- Experimental: methylphenidate treatment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Attention Deficit Hyperactivity Disorder
Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD
This study looks to examine whether or not INTUNIV extended release can help children aged 6-12 years diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) in improving Executive Function when added to their usual care…
- Trial name
- NCT01985581
- Testing
- Guanfacine extended release, Stimulant therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- JPM van Stralen Medicine Professional
Parkinson's Disease
Methylphenidate and Parkinson's Disease
The purpose of this trial is to determine if methylphenidate (MPD), a drug marketed in the U.S. to treat hyperactivity and narcolepsy, added to levodopa, will increase the beneficial effects of levodopa without bothersome side…
- Trial name
- NCT00359723
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
ADHD
Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity Disorder
The primary purpose of this study is to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.
- Trial name
- NCT00223561
- Testing
- methylphenidate
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Healthy
Emotional Effects of Methylphenidate and MDMA in Healthy Subjects
This study compares the interactive emotional/subjective effects of single doses of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and methylphenidate, a dopamine (DA) and norepinephrine (NE) transporter blocker, in healthy…
- Trial name
- NCT01465685
- Testing
- 3,4-Methylenedioxymethamphetamine, Methylphenidate
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Carboxylesterase 1 (CES1) Genotype, CES1 Activity
Impact of CES1 Genotype on Metabolism of Methylphenidate
The purpose of this study is to determine whether differences in the gene coding for the liver enzyme carboxylesterase 1 (CES1) means differences in the metabolism of methylphenidate, a CES1 dependent drug.
- Trial name
- NCT02147535
- Testing
- Methylphenidate
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Attention Deficit Hyperactivity Disorder
Comparing the Efficacy of Methylphenidate, Dextroamphetamine and Placebo in Children Diagnosed With ADHD
The study compares the efficacy of methylphenidate, dextroamphetamine and placebo on neuropsychological functioning and behavioral symptoms in 36 children diagnosed with ADHD within a double-blind cross-over design over six…
- Trial name
- NCT01220440
- Testing
- Methylphenidate, Dextroamphetamine
- Where
- 2 sites in Norway
- Volunteers
- 36 people
- Sponsor
- Ostfold Hospital Trust
Pharmacokinetics
A Study to Explore Plasma Levels of CONCERTA, Ritalin-SR and Novo-Methylphenidate ER-C in Healthy Volunteers
This is a study of blood plasma levels of methylphenidate in healthy volunteers over a 24 hour period after they take this medication.
- Trial name
- NCT01118702
- Testing
- Ritalin-SR, Concerta, Novo-Methylphenidate ER-C
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen-Ortho Inc., Canada
Motivation, Apathy
Motivation and Methylphenidate
The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.
- Conditions
- Motivation, Apathy, Impulsive Behavior
- Trial name
- MBB_MPH (NCT03190681)
- Testing
- Ritalin (methylphenidate)10Mg Tablet
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Attention Deficit Hyperactivity Disorder
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
This Phase 3 pivotal efficacy trial will examine the effects of HLD200 (methylphenidate) in patients aged 6-12 years with ADHD in a laboratory classroom setting.
- Trial name
- NCT02493777
- Testing
- HLD200 methylphenidate hydrochloride (MPH) Capsules
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
Attention Deficit Hyperactivity Disorder
Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)
Attention deficit with hyperactivity disorder (ADHD) is a very common behavioral problem during childhood. It is estimated that up to 80% of this disorder could be related to genetic factors.
- Trial name
- NCT00483106
- Testing
- Ritalin
- Where
- Canada
- Volunteers
- 885 people
- Sponsor
- McGill University
ADHD
Effect of Pycnogenol® on ADHD
This double blind, randomised controlled trial examines the effect of a commercially available nutritional supplement on behaviour of ADHD patients, as well as on their physical and psychiatric co-morbidities, and level of…
- Trial name
- NCT02700685
- Testing
- Pycnogenol, Methylphenidate
- Where
- 3 sites in Belgium
- Volunteers
- 88 people
- Sponsor
- Nina Hermans
Apathy, Diabetes
The Role of Apathy in Glycemic Control
In spite of several new medications and insulins for the control of blood sugars in patients with diabetes, a large number of patients do not have good control.
- Trial name
- NCT00844090
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- US Department of Veterans Affairs
Healthy, Attention Deficit Hyperactivity Disorder
Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits.
- Trial name
- NMAS (NCT01993108)
- Testing
- Methylphenidate, Naltrexone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Attention Deficit Hyperactivity Disorder
Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
The objective of this study is to compare the effect of Concerta (Osmotic Release Oral System Extended Release Methylphenidate HCL, OROS MPH) and Strattera (Atomoxetine) on the laboratory and ecological executive function in…
- Trial name
- NCT01065259
- Testing
- OROS MPH, Atomoxetine
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Peking University
Attention Deficit Disorder With Hyperactivity
A Safety and Effectiveness Study of Methylphenidate HCl Extended-release Tablets in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the effectiveness and safety of methylphenidate HCl extended-release tablets at five dose levels compared to placebo in adults with Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NCT00326391
- Testing
- methylphenidate hydrochloride extended-release tablets
- Volunteers
- 229 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Attention-Deficit/Hyperactivity Disorder (ADHD)
Does Active Parent Involvement in Deliberation and Choice Improve Medication Persistence for Their Child With ADHD
The purpose of the study is to determine whether active parent involvement in deliberation and choice improves subsequent medication persistence for their child with ADHD.
- Trial name
- NCT00631280
- Testing
- Choice, Recommendation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Attention Deficit Hyperactivity Disorder
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
This is an open-label study of the efficacy of Daytrana (methylphenidate transdermal system) for the treatment of attention and behavioral symptoms in children with Autism Spectrum Disorders.
- Trial name
- NCT00541346
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Attention Deficit Hyperactivity Disorder
Community-based Study Comparing Extended-release Methylphenidate and Atomoxetine in Children With Attention-deficit Hyperactivity Disorder
The purpose of this study was to better understand the treatment outcomes of extended-release methylphenidate and atomoxetine in children with attention-deficit hyperactivity disorder (ADHD) as evaluated by physicians and parents…
- Trial name
- NCT00866996
- Testing
- Methylphenidate extended-release; Atomoxetine
- Volunteers
- 1,323 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.