Clinical trials: Methylphenidate
Attention Deficit Hyperactivity Disorder
Impact of Attention Deficit/Hyperactivity Disorder and Substance Use Disorder on Motorcycle Traffic Accidents
The purpose of this study is to determine whether motorcycle drivers with ADHD are at a greater risk for motorcycle accidents, and whether this risk can be mitigated by treatment with methylphenidate.
- Trial name
- NCT00536419
- Testing
- Methylphenidate
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Federal University of Rio Grande do Sul
Attention Deficit Disorders With Hyperactivity, Attention Deficit Disorder
Event-related Potentials in Management of Children With Attention-deficit/Hyperactivity Disorder
The investigators try to objectively and scientifically explore various brain function impairments in ADHD children by electrophysiologic tests, with and without medication.
- Conditions
- Attention Deficit Disorders With Hyperactivity, Attention Deficit Disorder, Hyperkinetic Syndrome
- Trial name
- NCT01130467
- Testing
- methylphenidate, Atomoxetine, behavioral modification
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Attention Deficit Hyperactivity Disorder
A Study to Evaluate 3 Different Doses of JNJ-31001074 in the Treatment of Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the efficacy and safety/tolerability of 3 different dosages of JNJ-31001074 compared with placebo in adult patients with attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT00880217
- Testing
- Atomoxetine 80 mg/d, OROS methylphenidate HCl 54 mg/d, JNJ-31001074 3 mg/d
- Where
- 35 sites in United States
- Volunteers
- 430 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Oxygen Toxicity, Hypercapnia
Oxygen Toxicity: Mechanisms in Humans
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: How does the training of respiratory muscles affect oxygen toxicity? How do…
- Conditions
- Oxygen Toxicity, Hypercapnia, Seizures
- Trial name
- NCT05761756
- Testing
- Sleep Deprivation, Caffeine, Methylphenidate
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Duke University
Attention Deficit Hyperactivity Disorder
The Effect of Methylphenidate on Decision-making Ability of Attention Deficit Hyperactivity Disorder (ADHD) Adults
The aim of the study is to assess the effect of Methylphenidate on cognitive performance and decision-making ability of ADHD adults, and to compare this effect to the effect on healthy control adults.
- Trial name
- NCT01040702
- Testing
- methylphenidate, sweetener pill
- Where
- Israel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Attention Deficit/Hyperactivity Disorder (ADHD)
Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)
In contrast to mothers with Attention Deficit/Hyperactivity Disorder (ADHD), the impact of paternal ADHD in families and children with ADHD symptoms has not been studied, despite the prevalence of ADHD in males.
- Trial name
- NCT02675400
- Testing
- Vyvanse, Behavioral Parent Training, Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Attention Deficit Disorder With Hyperactivity
Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.
- Trial name
- NCT00031395
- Testing
- clonidine, methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Cincinnati
Attention Deficit Hyperactivity Disorder
Brain Dopamine Function in Adults With ADHD
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and…
- Trial name
- Brookhaven (NCT00580814)
- Testing
- Experimental: methylphenidate treatment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Attention Deficit Hyperactivity Disorder
Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD
This study looks to examine whether or not INTUNIV extended release can help children aged 6-12 years diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) in improving Executive Function when added to their usual care…
- Trial name
- NCT01985581
- Testing
- Guanfacine extended release, Stimulant therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- JPM van Stralen Medicine Professional
Attention Deficit Hyperactivity Disorder
Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD
Approximately 1-in-20 children worldwide have Attention Deficit Hyperactivity Disorder (ADHD), a condition associated with disabling inattention, hyperactivity and impulsivity.
- Trial name
- NCT05600881
- Testing
- Methylphenidate
- Volunteers
- 35 people
- Sponsor
- University of Dublin, Trinity College
Parkinson's Disease
Methylphenidate and Parkinson's Disease
The purpose of this trial is to determine if methylphenidate (MPD), a drug marketed in the U.S. to treat hyperactivity and narcolepsy, added to levodopa, will increase the beneficial effects of levodopa without bothersome side…
- Trial name
- NCT00359723
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Depression, Neurotoxicity
Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
RATIONALE: Stimulant drugs such as dextroamphetamine-amphetamine and methylphenidate may help improve memory, attention, and thinking problems caused by central nervous system (CNS) treatment for cancer, and may help decrease…
- Conditions
- Depression, Neurotoxicity, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00069927
- Testing
- Adderall-XR®, Concerta®
- Where
- 9 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of South Florida
ADHD
Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity Disorder
The primary purpose of this study is to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.
- Trial name
- NCT00223561
- Testing
- methylphenidate
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Central Nervous System Tumor, Pediatric, Fatigue
Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy
RATIONALE: Methylphenidate hydrochloride or modafinil may help reduce daytime sleepiness and improve the quality of life of patients with excessive daytime sleepiness after cancer therapy.
- Conditions
- Central Nervous System Tumor, Pediatric, Fatigue, Specific Disorders of Sleep
- Trial name
- NCT01348607
- Testing
- methylphenidate hydrochloride, modafinil
- Volunteers
- 1 people
- Sponsor
- University of South Florida
Attention Deficit Hyperactivity Disorder
Cognitive Behavioral Therapy for Adolescents With Attention-Deficit / Hyperactivity Disorder
Attention Deficit/ Hyperactivity Disorder (ADHD) is a common childhood psychiatric condition, which often persists into adolescence.
- Trial name
- NCT02566824
- Testing
- Cognitive Behavioural & Skills Training, Supportive Group Therapy, Treatment as Usual - community resources
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy
Functional Differences in Effortful Control
The purpose of this study was to learn more about the brain circuits involved with effortful control in healthy adult participants.
- Trial name
- FDEC (NCT01993147)
- Testing
- Dual task paradigm pilot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy
Emotional Effects of Methylphenidate and MDMA in Healthy Subjects
This study compares the interactive emotional/subjective effects of single doses of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and methylphenidate, a dopamine (DA) and norepinephrine (NE) transporter blocker, in healthy…
- Trial name
- NCT01465685
- Testing
- 3,4-Methylenedioxymethamphetamine, Methylphenidate
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Carboxylesterase 1 (CES1) Genotype, CES1 Activity
Impact of CES1 Genotype on Metabolism of Methylphenidate
The purpose of this study is to determine whether differences in the gene coding for the liver enzyme carboxylesterase 1 (CES1) means differences in the metabolism of methylphenidate, a CES1 dependent drug.
- Trial name
- NCT02147535
- Testing
- Methylphenidate
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Attention Deficit Disorder
The Characteristics of Prepulse Inhibition in Children and Adolescents Suffering From Attention Deficit Disorder
The purpose of this study is to show that Prepulse inhibition test of acoustic startle response is an indicator of objective diagnostic characteristics of attention deficit disorder in children and adolescents.
- Trial name
- PPI (NCT02344784)
- Testing
- SR-HLAB EMG, Methylphenidate
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- HaEmek Medical Center, Israel
Depression
Study of Methylphenidate as Add on Therapy in Depressed Cancer Patients
Primary Objective To determine the efficacy of Methylphenidate as add on therapy to mirtazapine in the treatment of depression in cancer patients under palliative care Hypothesis Methyphenidate add on to mirtazapine treated…
- Trial name
- NCT01497548
- Testing
- Methylphenidate
- Where
- 2 sites in Malaysia
- Volunteers
- 120 people
- Sponsor
- University of Malaya