Clinical trials: Methylphenidate
Attention Deficit Hyperactivity Disorder
Comparing the Efficacy of Methylphenidate, Dextroamphetamine and Placebo in Children Diagnosed With ADHD
The study compares the efficacy of methylphenidate, dextroamphetamine and placebo on neuropsychological functioning and behavioral symptoms in 36 children diagnosed with ADHD within a double-blind cross-over design over six…
- Trial name
- NCT01220440
- Testing
- Methylphenidate, Dextroamphetamine
- Where
- 2 sites in Norway
- Volunteers
- 36 people
- Sponsor
- Ostfold Hospital Trust
Attention Deficit Hyperactivity Disorder
Effectiveness of a Mobile Neurofeedback for ADHD Youth
Objective: Verification of ADHD Treatment Effectiveness of Mobile Neurofeedback to Subjects of Child and Youth with ADHD. Method: Mobile Neurofeedback Program is implemented for 165 ADHD patients aged 8 to 15 to verify their…
- Trial name
- NCT04469335
- Testing
- mobile neurofeedback, medication + mobile neurofeedback
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Seoul National University Childrens Hospital
Pharmacokinetics
A Study to Explore Plasma Levels of CONCERTA, Ritalin-SR and Novo-Methylphenidate ER-C in Healthy Volunteers
This is a study of blood plasma levels of methylphenidate in healthy volunteers over a 24 hour period after they take this medication.
- Trial name
- NCT01118702
- Testing
- Ritalin-SR, Concerta, Novo-Methylphenidate ER-C
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen-Ortho Inc., Canada
Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder
Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders
Attention Deficit/Hyperactivity Disorder (ADHD) is one the most prevalent mental disorders among children and adolescents, with a prevalence of 5% in western culture.
- Conditions
- Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder
- Trial name
- NCT02063945
- Testing
- Methylphenidate, Risperidone
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Sheba Medical Center
Motivation, Apathy
Motivation and Methylphenidate
The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.
- Conditions
- Motivation, Apathy, Impulsive Behavior
- Trial name
- MBB_MPH (NCT03190681)
- Testing
- Ritalin (methylphenidate)10Mg Tablet
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
ADHD
Acoustic and Vestibular Noise as Possible Non-pharmacological Treatment of ADHD in School Children
Noise benefit in ADHD Auditory noise benefit: The original findings from our research group, that auditory noise enhances cognitive performance in inattentive children without diagnosis as well as children with an ADHD diagnosis…
- Trial name
- NCT03425669
- Testing
- Stochastic Vestibular Stimulation, Active medication
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lund University
Attention Deficit Hyperactivity Disorder
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
This Phase 3 pivotal efficacy trial will examine the effects of HLD200 (methylphenidate) in patients aged 6-12 years with ADHD in a laboratory classroom setting.
- Trial name
- NCT02493777
- Testing
- HLD200 methylphenidate hydrochloride (MPH) Capsules
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
Attention Deficit Hyperactivity Disorder
Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)
Attention deficit with hyperactivity disorder (ADHD) is a very common behavioral problem during childhood. It is estimated that up to 80% of this disorder could be related to genetic factors.
- Trial name
- NCT00483106
- Testing
- Ritalin
- Where
- Canada
- Volunteers
- 885 people
- Sponsor
- McGill University
Cerebrovascular Accident
The Effect of Methylphenidate on Motor Learning in Stroke Patients
The purpose of the study is to determine whether methylphenidate facilitates so called short-term plasticity as measures with transcranial magnetic stimulation, in patients with stroke.
- Trial name
- NCT00396058
- Testing
- Methylphenidate
- Where
- 2 sites in Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Personality
Personality and Drug Use (PDU)
The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histories of substance use differentiate on personality assessments (current and…
- Trial name
- PDU (NCT05180149)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Quantified Citizen Technologies Inc.
Attention-Deficit/Hyperactivity Disorder
Real-World Evidence of Duration of Effect of Adhansia XR (Extended-Release) for Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to investigate the treatment effectiveness of Adhansia XR at month-2 after initiation, and the effectiveness of Adhansia XR overall and when compared with the active comparator group (Concerta) over…
- Trial name
- RE-DAX (NCT04507204)
- Testing
- Adhansia XR, Concerta
- Where
- 35 sites in United States
- Volunteers
- 267 people
- Sponsor
- Purdue Pharma LP
ADHD
Effect of Pycnogenol® on ADHD
This double blind, randomised controlled trial examines the effect of a commercially available nutritional supplement on behaviour of ADHD patients, as well as on their physical and psychiatric co-morbidities, and level of…
- Trial name
- NCT02700685
- Testing
- Pycnogenol, Methylphenidate
- Where
- 3 sites in Belgium
- Volunteers
- 88 people
- Sponsor
- Nina Hermans
Apathy, Diabetes
The Role of Apathy in Glycemic Control
In spite of several new medications and insulins for the control of blood sugars in patients with diabetes, a large number of patients do not have good control.
- Trial name
- NCT00844090
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- US Department of Veterans Affairs
Healthy, Attention Deficit Hyperactivity Disorder
Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits.
- Trial name
- NMAS (NCT01993108)
- Testing
- Methylphenidate, Naltrexone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Attention Deficit Hyperactivity Disorder
Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
The objective of this study is to compare the effect of Concerta (Osmotic Release Oral System Extended Release Methylphenidate HCL, OROS MPH) and Strattera (Atomoxetine) on the laboratory and ecological executive function in…
- Trial name
- NCT01065259
- Testing
- OROS MPH, Atomoxetine
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Peking University
Attention Deficit Disorder With Hyperactivity
A Safety and Effectiveness Study of Methylphenidate HCl Extended-release Tablets in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to evaluate the effectiveness and safety of methylphenidate HCl extended-release tablets at five dose levels compared to placebo in adults with Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NCT00326391
- Testing
- methylphenidate hydrochloride extended-release tablets
- Volunteers
- 229 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Attention-Deficit/Hyperactivity Disorder (ADHD)
Does Active Parent Involvement in Deliberation and Choice Improve Medication Persistence for Their Child With ADHD
The purpose of the study is to determine whether active parent involvement in deliberation and choice improves subsequent medication persistence for their child with ADHD.
- Trial name
- NCT00631280
- Testing
- Choice, Recommendation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Attention Deficit Hyperactivity Disorder
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
This is an open-label study of the efficacy of Daytrana (methylphenidate transdermal system) for the treatment of attention and behavioral symptoms in children with Autism Spectrum Disorders.
- Trial name
- NCT00541346
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Attention Deficit/Hyperactivity Disorder
Safety and Tolerability Study of Adhansia XR® Extended-Release Capsules in Children
The purpose of this study is to assess the long-term safety of Adhansia XR in children and to characterize the pharmacokinetics (PK) in 4 to 5 year-olds.
- Trial name
- NCT04987762
- Testing
- Adhansia XR
- Where
- 15 sites in United States
- Volunteers
- 103 people
- Sponsor
- Purdue Pharma LP
Attention Deficit Hyperactivity Disorder
Community-based Study Comparing Extended-release Methylphenidate and Atomoxetine in Children With Attention-deficit Hyperactivity Disorder
The purpose of this study was to better understand the treatment outcomes of extended-release methylphenidate and atomoxetine in children with attention-deficit hyperactivity disorder (ADHD) as evaluated by physicians and parents…
- Trial name
- NCT00866996
- Testing
- Methylphenidate extended-release; Atomoxetine
- Volunteers
- 1,323 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.