Clinical trials: Methylphenidate
ADHD
Multimodal Magnetic Resonance Imaging Study on the Neural Mechanisms of Remission in Children With ADHD
Attention-deficit/hyperactivity disorder(ADHD) is highly prevalent among children and adolescents and often associated with poor long-term outcomes in adulthood. it is thus a serious public health problem.
- Trial name
- NCT05229627
- Testing
- MPH, ATX
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Attention Deficit Disorder With Hyperactivity
CONCERTA (OROS Methylphenidate Hydrochloride) for the Treatment of Attention Deficit Hyperactivity Disorder in Adults
The purpose of this pilot study is to evaluate the safety, tolerability and potential effectiveness of CONCERTA® (methylphenidate hydrochloride extended-release tablets), a central nervous system (CNS) stimulant for the…
- Trial name
- NCT00246207
- Testing
- CONCERTA (OROS methylphenidate hydrochloride)
- Volunteers
- 32 people
- Sponsor
- Janssen-Ortho Inc., Canada
Attention Deficit Hyperactivity Disorder
Omega-3 Supplementation and Attention-deficit-hyperactivity Disorder (ADHD)
It is assumed that only 1/5 of children diagnosed with attention-deficit-hyperactivity disorder (ADHD) are treated. New treatment modalities are urgently needed.
- Trial name
- NCT00874536
- Testing
- omega-3 fatty acid alpha-linolenic acid (ALA)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Cocaine Addiction, Cocaine Abuse
Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates
Background: Brain imaging studies, genetic research, and investigations of stress have provided more information about the role of dopamine in processing reward and punishment, and in vulnerability to substance dependence.
- Trial name
- NCT00865332
- Where
- 2 sites in United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Attention Deficit Hyperactivity Disorder
Further Studies of Attention Deficit Disorder - Residual Type (RT)
The first phase was a double-blind crossover design of methylphenidate in the treatment of adult ADHD. The second phase consisted of an open-label extension trial of methylphenidate in adult ADHD.
- Trial name
- NCT00693212
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Utah
Attention Deficit Hyperactivity Disorder
Methylphenidate on Intracortical Inhibition in Methamphetamine Abusers Attention Deficit Hyperactivity Disorder (ADHD)
Previous studies using transcranial magnetic stimulation (TMS) with paired pulse protocols have shown that a conditioning TMS pulse applied to the human motor cortex changes the excitability of motor pathways from the motor…
- Trial name
- ADHD (NCT01651169)
- Testing
- methylphenidate tablets and Inter-stimulus Intervals (ISI)
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Tehran University of Medical Sciences
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Diabetes Mellitus, Alzheimer's Disease
Improving Function, Quality of Life, Glycemia in Diabetics With Dementia
The primary purpose of this study is to determine if the study medication Methylphenidate (Ritalin) will improve subject's blood-sugar control by improving their motivation more than placebo.
- Conditions
- Diabetes Mellitus, Alzheimer's Disease, Apathy, Dementia
- Trial name
- NCT00792662
- Testing
- Methylphenidate
- Sponsor
- University of Nebraska
Attention Deficit Hyperactivity Disorder, Generalized Anxiety Disorder
A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity
Other psychiatric disorders, including anxiety, often co-occur with adult ADHD; with 85% of ADHD patients having at least one other psychiatric condition.
- Conditions
- Attention Deficit Hyperactivity Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03785223
- Testing
- Methylphenidate Hydrochloride Controlled-Release Capsules
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Adult ADHD, Adult-onset ADHD With Mood Disorder
EEG-MRI Imaging of Methylphenidate Effects in Adult ADHD and Attentional Symptoms in Mood Disorders
Attention Deficit Hyperactivity Disorder (ADHD) in adults is a common psychiatric disorder, with important consequences in terms of quality of life, mental health (associated disorders and poorer response to treatment), family…
- Trial name
- ImAteM-TDA (NCT05832489)
- Testing
- Methylphenidate immediate release 25mg
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
PTSD
Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
In the present study, investigator will investigate the effects of methylphenidate (40 mg) on mPFC activity in healthy male volunteers during fear extinction using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT02021214
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Attention Deficit Hyperactivity Disorder, Reading Disabilities
Interventions for Children With Attention and Reading Disorders
The objective of this randomized clinical trial is to address unanswered questions about the relative effectiveness of treatments for children with both Attention Deficit Hyperactivity Disorder (ADHD) and significant reading…
- Trial name
- ICARD (NCT01133847)
- Testing
- Methylphenidate, Intensive reading instruction, Parent Training
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- The University of Texas Health Science Center, Houston
Attention Deficit Disorder With Hyperactivity, Tourette Syndrome
Methylphenidate for Treating Children With ADHD and Tourette Syndrome
This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder in children with both attention deficit hyperactivity disorder and Tourette syndrome.
- Trial name
- NCT00441649
- Testing
- Methylphenidate
- Volunteers
- 71 people
- Sponsor
- Stony Brook University
Apathy, Alzheimer's Disease
Apathy in Dementia Methylphenidate Trial (ADMET)
The Apathy in Dementia Methylphenidate Trial (ADMET) is a masked, placebo-controlled trial that will examine the efficacy and safety of methylphenidate for the treatment of clinically significant apathy in patients with…
- Trial name
- ADMET (NCT01117181)
- Testing
- Methylphenidate, Psychosocial intervention
- Where
- 3 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Attention Deficit Disorder With Hyperactivity
Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children
This study will determine the effectiveness of stimulant and nonstimulant medication in treating the symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents.
- Trial name
- NCT00183391
- Testing
- Atomoxetine, Methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fatigue, Cancer
Patient Controlled Methylphenidate for Cancer Related Fatigue: A Double Blind, Randomized, Placebo Controlled Trial
To determine the effectiveness of patient controlled methylphenidate as compared to placebo for the management of cancer related fatigue as determined by the Functional Assessment of Chronic Illness Therapy (FACIT)-F Fatigue…
- Trial name
- NCT05041946
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- M.D. Anderson Cancer Center
Attention Deficit Disorder With Hyperactivity
Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.
The primary purpose of this thirteen-week, open-label study is to test the hypothesis that quetiapine in combination with Oros methylphenidate will reduce aggressive symptoms in children and adolescents who have shown inadequate…
- Trial name
- NCT00550147
- Testing
- Oros Methylphenidate, quetiapine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Attention Deficit Hyperactivity Disorder, ADHD
Time Course of Response to Methylphenidate HCl ER Capsules in Children 6 to 12 Years With ADHD in Classroom Setting
The time course of response following one dose of a new methylphenidate hydrochloride extended release capsule is studied in children 6-12 years in a simulated laboratory classroom setting.
- Trial name
- NCT01269463
- Testing
- Methylphenidate Hydrochloride Extended Release Capsule
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Attention Deficit Disorder With Hyperactivity
Computer-assisted Cognitive Rehabilitation (CACR), Placebo CACR and Psycho-stimulants in the Treatment of ADHD
Current research aimed to compare the efficacy of computer-assisted cognitive rehabilitation (CACR), stimulant drugs and Placebo CACR on executive functions and clinical symptoms of children with attention deficit/hyperactivity…
- Trial name
- NCT01675804
- Testing
- Computerized cognitive rehabilitation, Ritalin
- Where
- Iran
- Volunteers
- 34 people
- Sponsor
- Allameh Tabatabai University
Attention Deficit Disorder With Hyperactivity (ADHD)
The Effect Of Methylphenıdate Treatment On Neuroınflammatıon Levels In Chıldren Wıth Attentıon Defıcıt Hyperactıvıty Dısorder
The aim of this study was to investigate the effect of treatment of ADHD with methylphenidate on neuroinflammation by examining the levels of Interleukin-6 (IL-6), S100B, Claudin-5 in serum samples of patients who were diagnosed…
- Trial name
- NCT07041333
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Enes Faruk ALTUNKILIÇ