Clinical trials: Methylphenidate, completed
Stroke
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to improve learning of movement skills and the adaptation processes in patients after stroke.
- Trial name
- NCT00715520
- Testing
- Transcranial Magnetic Stimulation (TMS), Carbidopa-Levodopa, Methylphenidate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Attention Deficit Disorder With Hyperactivity
Compliance Survey of ADHD Medication for Optimal Satisfaction (COSMOS)
The survey is designed to identify non-compliant Attention Deficit Hyperactivity Disorder (ADHD) patients who are currently on Immediate- Released Methylphenidate (IR-MPH) and observe any change in compliance after treating with…
- Trial name
- NCT00460720
- Testing
- Observational treatment compliance survey
- Volunteers
- 591 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder
Stimulant Medication Effects on Auditory Sensitivity in Teens With ADHD
The aims of this study are to evaluate auditory sensitivity in teenagers with ADHD using acoustic reflex thresholds (ART) and to examine the effects of ADHD stimulant medication on ART.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT04577417
- Testing
- ADHD stimulants, for example, amphetamine, dexmethylphenidate, dextroamphetamine, methylphenidate
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
ADHD, Substance Abuse
Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)
The purpose of this study is to determine the efficacy of osmotic-release methylphenidate (OROS-MPH) versus placebo for the treatment of ADHD in adolescents with SUD.
- Trial name
- NCT00264797
- Testing
- Methylphenidate (OROS-MPH)
- Where
- 12 sites in United States
- Volunteers
- 303 people
- Sponsor
- University of Cincinnati
Adult ADHD
Efficacy of Concerta in Treating ADHD in Mothers of Children With ADHD
This study involves a 7 week dose-response trial of Concerta™ methylphenidate for mothers of children with ADHD who have ADHD themselves.
- Trial name
- NCT00318981
- Testing
- Concerta
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, College Park
Attention-Deficit/Hyperactivity Disorder
Pharmacokinetic Study of Methylphenidate HCl Extended-Release Capsules in Children 4 to Under 6 Years of Age With ADHD
To assess the pharmacokinetics of a single dose of Aptensio XR® (methylphenidate hydrochloride extended-release) capsules under fed conditions in male or female children 4 to under 6 years of age with ADHD.
- Trial name
- PK003 (NCT02470234)
- Testing
- Methylphenidate HCl ER Capsules, 10 mg, Methylphenidate HCl ER Capsules, 15 mg, Methylphenidate HCl ER Capsules, 20 mg
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Drug Binding to DAT Receptors
Study of Dopamine Transporter Receptor Occupancy With Long-acting Dex-methylphenidate
The objectives of this study are to document the pharmacokinetics of the adequacy of DAT receptor occupancy d-MPH formulation in three doses (20 mg, 30 mg, and 40 mg) using PET scanning with C-11 Altropane as the ligand across a…
- Trial name
- NCT00593138
- Testing
- dex-methylphenidate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
ADHD - Inattentive Type, ADHD - Combined Type
Attention Deficit Disorder Medication Response Study
This study evaluates how children with Attention Deficit Disorder without Hyperactivity (ADD) respond to medication, and if their response is different from children who have problems with both hyperactivity and inattention.
- Trial name
- NCT01727414
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Alzheimer Dementia
A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.
Investigators are doing this research study to find out if methylphenidate (MPH) can help people with Mild Cognitive Impairment (MCI) or mild dementia likely due to Alzheimer's Disease (AD) and related disorders (ADRD).
- Trial name
- NCT03811847
- Testing
- Methylphenidate Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Disorder With Hyperactivity, Developmental Coordination Disorder
Co Morbid Attention Deficit and Hyperactivity Disorder(ADHD) and Developmental Co Ordination Disorder (DCD)
This study aims to establish and present the prevalence figures and demographics of the co-morbidity of ADHD and DCD. It further aims to design an exercise intervention, to be utilised in the management of the symptoms of both…
- Trial name
- NCT03595826
- Testing
- Neurostimulant pharmaceutical drugs
- Where
- South Africa
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Translational Electrophysiology
Novel Cross-Species Neurophysiological Assays of Reward and Cognitive Domains
The overarching goal of this multi-disciplinary research program is to develop and optimize new cross-species translational assessments of reward and cognition that will not only be assessed in parallel in humans and rats, but…
- Trial name
- NCT02855229
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Attention-Deficit/Hyperactivity Disorder, Drop-out
Treatment Drop-out and Missed Appointments Among Adults With ADHD
The investigators knowledge of factors associated with treatment drop-out and missed appointments among adults with Attention-Deficit/Hyperactivity Disorder (ADHD) within a naturalistic, clinical setting is very limited.
- Conditions
- Attention-Deficit/Hyperactivity Disorder, Drop-out, Non-adherence
- Trial name
- NCT02226445
- Testing
- Combined ADHD medication and psychosocial counseling
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- University of Aarhus
Attention Deficit Hyperactivity Disorder
Gene-environment Interactions and Brain Functional Connectivity in Attention Deficit Hyperactivity Disorder
The aims of the current study are to examine gene-environment interactions associated with norepinephrine (NE) system genes (ADRA2A, SLC6A2) in ADHD, and to evaluate whether genetic changes in norepinephrine pathway are…
- Trial name
- NCT01912352
- Testing
- Methylphenidate
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Attention-deficit/Hyperactivity Disorder
Cost-Effectiveness Study Of The Treatment Of Attention Deficit/Hyperactivity Disorder In Brazil
This study is an open-label, 6 month trial, of immediate release methylphenidate (MPH-IR) for children with ADHD aimed at assessing whether the observable behavioral changes seen during treatment are associated with potentially…
- Trial name
- NCT01228604
- Testing
- methylphenidate (Ritalin®)
- Where
- Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Attention Deficit Hyperactivity Disorder, Anxiety, Separation
Treatment of Youth With ADHD and Anxiety
The purpose of this NIMH-sponsored pilot study is to collect information on the efficacy and safety of drug treatments for children and adolescents who suffer from both ADHD and anxiety disorders.
- Conditions
- Attention Deficit Hyperactivity Disorder, Anxiety, Separation, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00012584
- Testing
- methylphenidate, fluvoxamine
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Hyperactivity Disorder
CONCERTA Lab School Study
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT00799487
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Mania
Methylphenidate for the Treatment of Acute Mania
This study aims at evaluating the efficacy and safety of methylphenidate in the initial treatment of acute mania in patients with bipolar affective disorders.
- Trial name
- NCT01541605
- Testing
- methylphenidate
- Where
- 10 sites in Belgium, Germany and 2 more
- Volunteers
- 42 people
- Sponsor
- Michael Kluge
Attention Deficit Hyperactivity Disorder
CBT Group for Adolescents With ADHD: a Randomized Controlled Trial
This is the first randomized controlled study that tests the efficacy of a cognitive-behavioral group therapy (CBT) on adolescents with ADHD who were in pharmacological treatment but still presented persistent symptoms.
- Trial name
- NCT02172183
- Testing
- Psychopharmacological treatment, CBT group
- Where
- Spain
- Volunteers
- 119 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Attention Deficit Hyperactivity Disorder
Long Acting Stimulant Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Young Children
This is a pilot study evaluating the effectiveness, safety, and tolerability of Ritalin LA in treating Attention Deficit Hyperactivity Disorder (ADHD) in 4 and 5 year old children.
- Trial name
- NCT00754208
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska
Attention Deficit/Hyperactivity Disorder Combined Type, ADHD Predominantly Inattentive Type
The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to investigate the familial response to Methylphenidate treatment (Ritalin IR) in two aspects: ADHD symptom's improvement and side-effects development.
- Conditions
- Attention Deficit/Hyperactivity Disorder Combined Type, ADHD Predominantly Inattentive Type, ADHD Predominantly Hyperactivity Type, ADHD-not Other Specified
- Trial name
- NCT01554046
- Testing
- Methylphenidate- Ritalin IR (Immediate Release)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center