Clinical trials: Metronidazole
Helicobacter Eradication
Prospective Study : Helicobacter Pylori Eradication Therapy in Accordance With Past Antibiotics Use
Prospective study : Helicobacter pylori eradication therapy in accordance with past antibiotics use.
- Trial name
- NCT01938534
- Testing
- Helicobacter pylori eradication
- Where
- South Korea
- Volunteers
- 440 people
- Sponsor
- Ajou University School of Medicine
Chronic Pouchitis, Pouchitis
Fecal Microbiota Transplant for Patients With Chronic Pouchitis
The purpose of this research study is to assess the safety and efficacy of fecal microbiota transplant (FMT) in the treatment of chronic pouchitis.
- Trial name
- NCT05829109
- Testing
- Fecal Microbiota Transplant (FMT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Maia Kayal
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Hypo-METRICS: Hypoglycaemia - Measurement, ThResholds and ImpaCtS
Hypoglycaemia or low blood glucose, and its fear are major barriers to achieving optimal glucose control. New technology, such as continuous glucose monitors (CGM), help to better identify hypoglycaemia and develop strategies to…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hypoglycemia, Hypoglycemia Unawareness
- Trial name
- Hypo-METRICS (NCT04304963)
- Testing
- NO intervention - observational study
- Where
- United Kingdom
- Volunteers
- 602 people
- Sponsor
- King's College London
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Recurrent Prostate Carcinoma, Stage I Prostate Cancer
A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer
Vaccines made from a gene-modified virus may help the body build an effective immune response to kill tumor cells. Biological therapies, such as GM-CSF, may stimulate the immune system in different ways and stop tumor cells from…
- Conditions
- Recurrent Prostate Carcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT00108732
- Testing
- Bicalutamide, Goserelin Acetate, Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Ulcerative Colitis
Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative Colitis
This is a prospective unblinded, randomized trial for the use of Fecal Microbiota Transplantation (FMT) for the treatment of Ulcerative Colitis (UC), in combination with or without antibiotic pretreatment.
- Trial name
- NCT03006809
- Testing
- Fecal Microbiota Transplantation (FMT), OpenBiome, pretreatment antibiotics
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Najwa Elnachef
Hip Injuries, Fractures, Hip
Mitigation of Major Hip Injury Due to Fall With a Smart Belt
Multi-center, comparative, non-significant risk adaptive study with retrospective controls. After providing informed consent and being screened for eligibility, intervention subjects will be prescribed and provided an…
- Conditions
- Hip Injuries, Fractures, Hip, Fall Injury, Fall Risk
- Trial name
- NCT05245097
- Testing
- Tango Belt, Standard of Care (SOC)
- Where
- 10 sites in United States
- Volunteers
- 471 people
- Sponsor
- ActiveProtective Technologies, Inc
Gastric/Duodenal Ulcer, Gastric MALT Lymphoma, Idiopathic Thrombocytopenic Purpura, or H. Pylori Gastritis, and Other
Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
The purpose of this study is to evaluate the safety and efficacy on participants receiving first-line eradication and second-line eradication including vonoprazan (Takecab) tablets (triple therapy) in the routine clinical setting.
- Trial name
- NCT03219723
- Testing
- Vonoprazan, Amoxicillin hydrate, Clarithromycin
- Where
- Japan
- Volunteers
- 560 people
- Sponsor
- Takeda
Helicobacter Pylori Infection
Triple Therapy Versus Quadruple Therapies in the First Line Therapy of Helicobacter Pylori Infection
Whether non-bismuth quadruple therapy (concomitant therapy) is more effective than bismuth quadruple therapy or triple therapy for 14 days remains unknown.
- Trial name
- NCT01906879
- Testing
- triple, quadruple, non-bismuth quadruple therapy
- Where
- 10 sites in Taiwan
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Implementation Science, Contact Tracing
Developing and Testing a Social Network Data Capture Tool to Improve Partner Services: a Preliminary Pilot Implementation
This study conducted a preliminary pilot implementation which integrated our existing social network software - Network Canvas - into Chicago Partner Services in order to understand the feasibility and acceptability of this…
- Conditions
- Implementation Science, Contact Tracing, Public Health System Research
- Trial name
- NCT06659003
- Testing
- Pilot Implementation of Network Canvas into HBH Partner Services
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Northwestern University
Cystic Fibrosis
Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome
The goal of this observational study is to learn about the effects of a specific cystic fibrosis therapy (Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy) on chronic sinonasal disease.
- Trial name
- NCT05982795
- Testing
- Nasal endoscopy with microbiome swab and mucus collection through filter paper and sponge, Olfactory Function Testing, Survey Completion
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
- Trial name
- NCT06524895
- Testing
- Medical Reiki
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Albert Einstein College of Medicine
Ischemia and Non-obstructive Coronary Arteries
Vascular Endothelial Inflammation and Health Status In INOCA (VISION-INOCA)
The purpose of this study is to evaluate coronary artery and peripheral vein vascular endothelial profiles in patients with ischemia with non-obstructive coronary arteries (INOCA) who undergo coronary function testing (CFT).
- Trial name
- NCT07586241
- Testing
- Invasive coronary angiography, Coronary Artery Endothelial Cell Sampling, Fitbit
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- NYU Langone Health
Helicobacter Pylori Infection
Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication
The researchers collect treatment-naive H.pylori-positive patients from the outpatient clinic. The subjects were randomized to receive a 10-day or 14-day course of quadruple eradication therapy.
- Trial name
- NCT05049902
- Testing
- Amoxicillin, Clarithromycin, Tetracycline
- Where
- 6 sites in China
- Volunteers
- 1,300 people
- Sponsor
- Shandong University
Hepatic Disease, Biliary Disease
Development and Prospective Validation of an AI-Based Diagnostic Model for Hepato-Pancreato-Biliary Diseases
The rapid advancement of artificial intelligence (AI) has expanded its applications in healthcare, particularly in diagnostic assistance, intelligent triage, and patient interaction.
- Conditions
- Hepatic Disease, Biliary Disease, Pancreas Disease, Artificial Intelligence (AI) in Diagnosis
- Trial name
- NCT07716670
- Testing
- AI Integration type 1, AI Integration type 2
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anastomotic Leak, Microbial Colonization
SURGIcal COmplication and MIcrobiome ChangeS in Colorectal Surgery
The microbiome, the collection of microorganisms that live in our gut, plays an important role in maintaining our health, proper nutrient absorption, nutrient turnover and immunity.
- Trial name
- Surgi-Comics (NCT05779254)
- Testing
- Neomycin Sulfate
- Where
- 3 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Uzsoki Hospital
Coronary Artery Disease (CAD)
Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study
Coronary artery disease occurs when fatty deposits (plaques) build up inside the arteries that supply blood to the heart. Some plaques remain stable, while others continue to grow or become more likely to rupture, which can lead…
- Trial name
- POSSEM (NCT07864051)
- Testing
- PCCTA scan, Endothelial cell isolation from peripheral blood sample
- Where
- United Kingdom
- Volunteers
- 270 people
- Sponsor
- Queen Mary University of London
Chronic Periodontitis
Dose and Duration of Metronidazole and Amoxicillin for Treatment of Chronic Periodontitis
The aim of this study was to compare the clinical and microbiological outcomes of different dosages of metronidazole (MTZ) and of the duration of the systemic administration of MTZ and amoxicillin as adjunct to scaling and root…
- Trial name
- NCT02735395
- Testing
- Scaling and root planing (SRP), Metronidazole 250 (7 days), Metronidazole 400 (7 days)
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- University of Guarulhos
Inflammatory Bowel Disease (IBD)
Personalized Exercise Coaching to Improve Quality of Life in Pediatric IBD
The primary objective of this research is to gain novel insights into the potential of physical activity in reducing fatigue, improving QoL and GI manifestations in children with IBD.
- Trial name
- FIT4IBDKids (NCT07355101)
- Testing
- Intake session to define individualized physical activity goals, Personalized Motivational Coaching, 24 Week Exercise Programme
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universiteit Antwerpen
Lung Cancer
Vaccine Therapy, Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed With Surgery
RATIONALE: Vaccines made from a gene-modified virus may make the body build an immune response to kill tumor cells. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop tumor cells from…
- Trial name
- NCT00091039
- Testing
- recombinant fowlpox GM-CSF vaccine adjuvant, recombinant fowlpox-CEA(6D)/TRICOM vaccine, recombinant vaccinia-CEA(6D)-TRICOM vaccine
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
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