Clinical trials: Metronidazole
Colorectal Neoplasms
Trial of Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery: Oral and Systemic Versus Systemic Antibiotics
The purpose of this study is to determine optimal prophylactic antibiotics administration method in elective laparoscopic colorectal surgery.
- Trial name
- NCT00508690
- Testing
- cefmetazole, kanamycin/metronidazole
- Where
- 5 sites in Japan
- Volunteers
- 584 people
- Sponsor
- Japan Multinational Trial Organization
Anxiety, Memory
Prediction of Anxiety and Memory State
The purpose of this study is to look at how signals in the brain, body, and behavior relate to anxiety and memory function. This project seeks to develop the CAMERA (Context-Aware Multimodal Ecological Research and Assessment)…
- Conditions
- Anxiety, Memory, Epilepsy
- Trial name
- CAMERA (NCT06551090)
- Testing
- CAMERA (Context-Aware Multimodal Ecological Research and Assessment)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Perianal Abscess, Anal Fistula
Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess
The goal of this clinical trial is to learn if antibiotics can prevent the formation of fistula-in-ano after incision and drainage of a first time of perianal abscess in adults.
- Trial name
- RAPID (NCT07704359)
- Testing
- Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Illinois Chicago
Erythemato-telangiectatic Rosacea
Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients
This study will evaluate the safety, tolerability and efficacy of BFH772 after 12 weeks of treatment as compared to an active control and vehicle in patients with erythemato-telangiectatic rosacea.
- Trial name
- NCT01449591
- Testing
- BFH772 1% ointment, Vehicle ointment, Noritate® 1% cream
- Where
- 6 sites in United States
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure With Reduced Ejection Fraction
Digital Remote Management Versus Usual Care for Optimization of Guideline-directed Medical Therapy in Patients With Heart Failure and Reduced Ejection Fraction: a Multicentre, Randomised, Controlled Trial (DigiCare-HFrEF)
DigiCare-HFrEF is an investigator-initiated, multicentre, randomised, open-label, endpoint-blinded, superiority trial designed to evaluate whether a structured digital remote-management platform can optimise guideline-directed…
- Trial name
- DigiCare-HFrEF (NCT07352891)
- Testing
- Digital Remote Management
- Where
- 6 sites in China
- Volunteers
- 252 people
- Sponsor
- Beijing Anzhen Hospital
Helicobacter Pylori Infection
Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection
Reverse hybrid therapy is a one-step two-phase treatment for Helicobacter pylori infection with less cost than standard triple therapy.
- Trial name
- REHYTRI (NCT02359435)
- Testing
- Reverse hybrid therapy, Standard triple therapy
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Risky Health Behavior, Substance Use Disorders
The STop UNhealthy Substance Use Now Trial
The STop UNhealthy (STUN) Substance Use Now Trial (STUN II) is a multisite trial aiming to evaluate the comparative effectiveness of the following strategies for improving the implementation of screening and interventions for…
- Conditions
- Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder
- Trial name
- STUN II (NCT06524232)
- Testing
- Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
- Where
- 3 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Self Efficacy
Genotypic Resistance Guided Therapy in Helicobacter Pylori Eradication
We aimed to compare the efficacy of genotypic resistance guided sequential therapy vs. empiric therapy in the third line therapy.
- Trial name
- NCT01725906
- Testing
- empirical therapy, Genotypic resistance guided therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 450 people
- Sponsor
- National Taiwan University Hospital
Osteoarthritis, Hip
Evaluation of Stability of Two Uncemented Hip Implants Used for Total Hip Arthroplasty
The purpose of this study is to measure quantitatively the implant stability and implant related remodeling of the periprosthetic femoral bone of the new uncemented Echo® Bi-Metric® Full proximal Profile total hip arthroplasty…
- Trial name
- NCT02656771
- Testing
- Echo Bi-Metric
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sexually Transmitted Infections, Schistosoma Haematobium
Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
A cross-sectional study of urogenital schistosomiasis and sexually transmitted infections (STI) prevalence and associated morbidity in a rural community in Madagascar.
- Trial name
- FGS/MGS/STI (NCT00713999)
- Testing
- Treatment with anti-STI and anti-schistosoma regimens
- Where
- Madagascar
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Metastatic Cancer, Palliative
Patient Reported Outcomes/Metrics Program Trial
This is an observational study to investigate if it is feasible to recruit 100 patients receiving radiotherapy (RT) to metastatic disease to wear Hexoskin and if Hexoskin will facilitate the monitoring, detection and early…
- Trial name
- PROMPT (NCT04983199)
- Testing
- Hexoskin Medical System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Breast Neoplasms, Metastases, Neoplasm
Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer
This study will evaluate the effectiveness of chemotherapy and a combination of vaccines to treat metastatic breast cancer (breast cancer that has spread beyond the breast) in patients whose cancer cells have a protein called…
- Trial name
- NCT00048893
- Testing
- recombinant fowlpox-CEA(6D)/TRICOM vaccine, recombinant vaccinia-CEA(6D)/TRICOM vaccine, filgrastim
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Abortion, Septic
The Use of Antibiotics After Hospital Discharge in Septic Abortion
The use of antibiotics in post-partum infection has been abbreviated. After 48 hours of clinical improvement, the patient is discharged from the hospital without antibiotics. No trials has been found in cases of septic abortion.
- Trial name
- APA (NCT00353743)
- Testing
- doxycycline plus metronidazole
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Helicobacter Pylori Infection
Tailored Therapy for Helicobacter Pylori in Children
This study is designed to compare the eradication rates，safety and compliance of tailored therapy to those of standard triple therapy in children with H. pylori infection.
- Trial name
- NCT02635191
- Testing
- Tailored Group, Standard group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Children's Hospital
Bacterial Vaginosis
Vaginal lIve Biotherapeutic RANdomized Trial
The goal of this randomized clinical trial is to evaluate safety and biologic effect of a multi-strain vaginal L. crispatus live biotherapeutic product (LBP) in people receiving antibiotic treatment for bacterial vaginosis (BV).
- Trial name
- VIBRANT (NCT06135974)
- Testing
- LC106, LC115, Metronidazole Oral
- Where
- 2 sites in United States, South Africa
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Abnormal Vaginal Flora, Clindamycin Vs Metronidazole
Comparison Between Oral Clindamycin Vs Metronidazole for the Treatment of Abnormal Vaginal Flora in High Risk Pregnancies
Abnormal vaginal flora is a risk factor for preterm labor. Therefore, in high risk pregnancies for preterm labor the diagnosis and treatment of abnormal flora is indicated.
- Conditions
- Abnormal Vaginal Flora, Clindamycin Vs Metronidazole, High Risk Pregnancies for Preterm Labor
- Trial name
- NCT01722708
- Testing
- Clindamycin, Metronidazole
- Where
- 2 sites in Israel
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Diabetic Foot Ulcer
Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection
The purpose of this study is to determine whether Garamycin Sponge (Gentamicin-Collagen sponge) in combination with antibiotics is safe and effective in treating moderate and severe diabetic foot infections.
- Trial name
- NCT01951768
- Testing
- Garamycin Sponge (Gentamicin-Collagen sponge), Systemic Antibiotic
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University Hospital, Geneva
Secondary Prevention of Coronary Heart Disease
Artificial Intelligence-Enhanced Management for Coronary Heart Disease (AIM-CHD) : Impact on Cholesterol and Other CHD Risk Factors
The goal of this clinical trial is to find out if an artificial intelligence (AI)-enhanced mobile app can help people with coronary heart disease (CHD) better manage their health after being discharged from the hospital.
- Trial name
- AIM-CHD (NCT06686056)
- Testing
- AIM-CHD Mobile Health Intervention, Usual post-discharge care
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cytochrome P450 Phenotype and Genotype Metrics
Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes
The Cytochrome P450 enzymes are responsible for the metabolism of a wide range of drugs and other xenobiotics. Genetic variants of the encoding P450 genes have shown to influence the rate of metabolism of many clinically used…
- Trial name
- NCT00981929
- Testing
- Tramadol, Omeprazole, losartan, caffeine, Tramadol, omeprazole, losartan, caffeine
- Where
- Denmark
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Prostate Cancer Patients
C-Acetate PET/CT Imaging to Evaluate Treatment Changes in Prostate Cancer
Patients with castrate resistant prostate cancer (CRPCA) with osseous metastatic disease planning to undergo Ra-223 therapy may be eligible for this study.
- Trial name
- NCT02715583
- Testing
- 11C-Acetate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
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