Clinical trials: Metronidazole
Revascularization
Regeneration of Immature Teeth. Case Series
This clinical study aims to investigate the predictability of revascularization procedure of immature necrotic human permanent teeth with apical periodontitis.
- Trial name
- NCT03507556
- Testing
- Triple paste and induced bleeding, Triple Paste metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Helicobacter Pylori Infection, Antimicrobial Susceptibility Testing
Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment
Helicobacter pylori (H. pylori), which infects about 50% of the global population, has been recognized as a main risk factor of multiple gastric pathologies, especially non-cardiac gastric cancer.
- Trial name
- NCT02988089
- Testing
- Clarithromycin susceptibility dependant strategy, 2 susceptible antibiotics (amoxicillin, clarithromycin, metronidazole, tinidazole,levofloxacin, furazolidone and tetracycline ), proton pump inhibitor (PPI) and Colloidal Bismuth Pectin
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Shandong University
Peri-Implantitis
Flapless Surgical Treatment of Peri-implantitis
Aim: To evaluate the effectiveness of a flapless surgical approach in the treatment of peri-implantitis and to explore the factors influencing disease resolution.
- Trial name
- NCT06093360
- Testing
- flapless surgery
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Universidad Complutense de Madrid
HIV Coinfection
HIV And Parasitic Infection (HAPI) Study
The overall goal of this study is to determine if periodic de-worming of persons living with HIV in intestinal parasite-endemic regions will lead to decreased morbidity and mortality associated with HIV by reducing immune…
- Trial name
- HAPI (NCT05323396)
- Testing
- Antiparasitic medication
- Where
- Malawi
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Incomplete Root Formation of Anterior Teeth
Efficacy of Combined Scaffolds and Sodium Hypochlorite in Regenerative Endodontics of Immature Teeth
The aim of the study is to evaluate the efficacy of combinations of different scaffolds (blood clot, platelet rich fibrin, collagen) and sodium hypochlorite concentrations (0.5%- 2.5%) in regenerative endodontics of immature…
- Trial name
- NCT05803525
- Testing
- Intra-canal medication protocol
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tanta University
Movement Disorders (Incl Parkinsonism)
Correlation of Motor Metrics and Neurological Data
This is a pilot study to collect data with the Ceraxis product and standard movement disorders tests in order to prove and codify potential correlations.
- Trial name
- COMMAND (NCT05462080)
- Testing
- Ceraxis product
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Ceraxis Health, Inc
Intra-abdominal Infections
Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI
This is a Phase 3, randomized, double-blind, multicenter, positive control study to assess the efficacy, safety, and pharmacokinetics of Meropenem and Pralurbactam compared with Ceftazidime-avibactam in combination with…
- Trial name
- NCT06633718
- Testing
- Meropenem and Pralurbactam, Saline, Ceftazidime-avibactam
- Where
- China
- Volunteers
- 786 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Tooth, Nonvital
Endodontic Regenerative Procedure for Immature Non-vital Teeth
In this clinical trial the investigators will evaluate an alternate treatment option, which was developed for teeth with incomplete roots, called Regenerative Endodontic Procedure (REP).
- Trial name
- NCT03425123
- Testing
- Regenerative Endodontic Procedure (REP)
- Where
- United States
- Sponsor
- Boston University
Cardiovascular Risk Factor
Virtual Lifestyle Intervention for Weight Management and Cardiovascular Heal
This is a 90-day, single-arm, open-label, fully virtual community lifestyle intervention study evaluating the effects of a multicomponent lifestyle intervention on weight management and cardiovascular health.
- Trial name
- NCT07572721
- Testing
- Multicomponent Virtual Lifestyle Intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truemedicine Inc
Prevention of Postpartum Sepsis
Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection
Randomised controlled trial to investigate the efficacy of adding metronidazole pre-operatively to kefazolin in reducing postpartum infection
- Trial name
- NCT04792710
- Testing
- Metronidazole
- Where
- South Africa
- Volunteers
- 1,000 people
- Sponsor
- University of Pretoria
Hormone-Resistant Prostate Cancer, Prostate Adenocarcinoma
Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
This randomized phase II trial studies how well docetaxel and prednisone with or without vaccine therapy works in treating patients with hormone-resistant prostate cancer that has spread to other parts of the body.
- Conditions
- Hormone-Resistant Prostate Cancer, Prostate Adenocarcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
- Trial name
- NCT01145508
- Testing
- Docetaxel, Laboratory Biomarker Analysis, Prednisone
- Where
- 14 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Bacterial Vaginosis (BV)
LUXSOL(TM) Topical Cream for the Treatment of Symptomatic Bacterial Vaginosis; A Proof of Concept Study
LUXSOL Cream may be useful for the treatment of bacterial Vaginosis. In this study, LUXSOL Cream is compared to a control arm group using metronidazole cream.
- Trial name
- NCT02197182
- Testing
- LUXSOL copper containing cream, Metronidazole gel
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- CDA Research Group, Inc.
Periodontitis
Systemic Probiotics in the Periodontal Treatment
The aim of this multicenter randomized clinical trial is to evaluate the clinical, microbiological and immunological effects of probiotics as an adjunct to Scaling and Root Planing alone or in combination with Metronidazole and…
- Trial name
- NCT03733379
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- 2 sites in Brazil
- Volunteers
- 176 people
- Sponsor
- Belén Retamal-Valdes
Periodontal Diseases, Aggressive Periodontitis
Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis.
Treatment of smoker patients with AgP is considered a challenge to periodontists. To date, only one controlled clinical study (De Genaro Modanese et al., 2016) evaluated the effect of full mouth ultrasonic debridment (FMUD) on…
- Trial name
- NCT04051255
- Testing
- full mouth ultrassonic debridement associated to Amoxicilin 500 + Metronidazole 400 mg
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Glaucoma, Age Related Macular Degeneration
Assessment of Visual Function With a Portable Brain-computer Interface
1. The purpose of this study is to evaluate the nGoggle's accuracy and repeatability in detecting visual function loss. In addition, the ability to stage glaucomatous damage and investigate the relationship between nGoggle…
- Conditions
- Glaucoma, Age Related Macular Degeneration, Optic Neuropathy, Retinal Degeneration
- Trial name
- NCT03760055
- Testing
- nGoggle
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NGoggle
Red Blood Cell Transfusions
Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit
Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and…
- Trial name
- TRIP (NCT07108374)
- Testing
- Implementation strategies to increase use of transfusion recommendations
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Pilonidal Sinus
Metronidazole Ointment in Non-healing Pilonidal Sinus Wounds
Title of Study: Randomised, double-blind, placebo-controlled trial evaluating the effects of metronidazole ointment in facilitating resolution on non-healing pilonidal sinus wounds Medical Condition Under Investigation…
- Trial name
- NCT04273997
- Testing
- Metronidazole 10% ointment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- S.L.A. Pharma AG
Peri-Implantitis, Implant Complication
Diode Laser for Treatment of Peri-implantitis
The primary objective is to evaluate the clinical and patient-centered outcomes of non-surgical mechanical debridement with adjunctive repeated diode laser application (test) in comparison with conventional surgical treatment and…
- Trial name
- LAS (NCT03383120)
- Testing
- Laser treatment, Surgical treatment with adjunctive systemic antibiotics
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Geneva, Switzerland
Persistence of Infection With Helicobacter Pylori
The Role of Cathepsin X in Infection With the Helicobacter Pylori
The immune response to Helicobacter pylori (Hp) importantly determines the pathogenesis of infection as well as the success of antibiotic eradication of the bacteria.
- Trial name
- NCT01137942
- Testing
- clarithromycin, metronidazole, proton pump inhibitor
- Where
- Slovenia
- Volunteers
- 14 people
- Sponsor
- University Medical Centre Ljubljana
Antibacterial Agents, Ambulatory Care
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Many clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus.
- Trial name
- NCT06144242
- Testing
- Feedback on RTD metric
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Livorsi
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