Clinical trials: Metronidazole
Obese Adults
Evaluation of the Axomove Therapy Medical Device to Facilitate Adapted Physical Activity for Patients With Obesity
Background: Obesity affects 18.1% of adults in France and leads to numerous chronic complications as well as functional limitations (fatigability, dyspnea).
- Trial name
- ON-TRAC (NCT07903025)
- Testing
- Axomove Therapy, Standard multidisciplinary medical care
- Where
- 8 sites in France
- Volunteers
- 184 people
- Sponsor
- Axomove
Periodontal Pocket
The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis
Aim of the present study is evaluate the use of erythritol powder with/without the adjunct of local metronidazole in the treatment of periodontal pockets.
- Trial name
- NCT02023840
- Testing
- metronidazole gel, ultrasonics, erythritol
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Proed, Torino, Italy
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Aggressive Periodontitis
Antimicrobial Photodynamic Therapy in Treatment of Aggressive Periodontitis (Stage III, Grade C Periodontitis)
Treatment of aggressive periodontitis (stage III, grade C periodontitis) represents a big challenge. The aim of the study was to compare the long-term results of antimicrobial photodynamic therapy (aPDT) and antibiotic therapy as…
- Trial name
- NCT05655338
- Testing
- antimicrobial photodynamic therapy, systemic antibiotics
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Ventilator Associated Pneumonia
Risk Factors and Common Preventive Measures for Ventilator Associated Pneumonia in Patients With Severe Traumatic Brain Injury
The primary objective of this study is to assess the incidence of VAP in patients with TBI and to identify risk factors for developing VAP in this specific patient population (types of co-injuries in patients with multiple trauma…
- Trial name
- NCT03266380
- Testing
- observational
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Metabolic Syndrome (MetS)
Use of a Mobile Application for Tracking Physical Activity in the Management of Metabolic Syndrome in Primary Care
This study will explore whether integrating a mobile app to track physical activity-recommended by family doctors during routine primary care visits-can help individuals with metabolic syndrome become more active.
- Trial name
- IMAFIL (NCT07236450)
- Testing
- Mobile Application and Wearable Device for Physical Activity Monitoring
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Andreia Lobo
Melanoma, Non-small Cell Lung Cancer
Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation
The goal of this prospective study to investigate the use of circulating tumor DNA (ctDNA) to guide end of therapy decisions in patients with melanoma or non-small-cell lung cancer.
- Trial name
- NCT06146920
- Testing
- Evaluation of ctDNA using the F1T after 1 year of immunotherapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Circadian Rhythm Disorders
Daytime Bright Light, Circadian Abnormalities, and Delirium in Medical ICU Patients
To determine if daytime bright light will promote circadian alignment and shorten or prevent delirium.
- Trial name
- NCT03684460
- Testing
- Daytime Bright Light, Usual Light
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Bladder Cancer
Metabolism Evaluation Through Resting Indirect Calorimetry in Bladder Cancer (METRICS)
This study is being done to learn more about energy needs and muscle function during treatment for bladder cancer. These insights can help improve future patient care.
- Trial name
- METRICS (NCT06721260)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Ischemic Heart Disease
Early Prediction of Major Adverse Cardiovascular Events Using Remote Monitoring
Usual care may not identify subtle clinical changes that precede a major adverse cardiovascular event (MACE). Therefore investigators will explore the effectiveness of using biomarkers, patient reported outcomes (PROs), and…
- Trial name
- NCT03064360
- Testing
- Laboratory Biomarker Analysis, Patient Activity, Questionnaires
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Helicobacter Pylori Infection
Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment
Standard triple therapy including a proton pump inhibitor (PPI) and clarithromycin with either amoxicillin or metronidazole are no longer recommended as empirical first-line therapy to treat Helicobacter pylori infection because…
- Trial name
- NCT02732249
- Testing
- Esomeprazole, Bismuth Potassium Citrate, Clarithromycin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Metastatic gpNMB Over-expressing Triple Negative Breast Cancer
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer
The main purpose of this study is to see whether CDX-011 (glembatumumab vedotin, an antibody-drug conjugate) is effective in treating patients who have advanced Triple-Negative Breast Cancer (TNBC), and whose tumor cells make a…
- Trial name
- METRIC (NCT01997333)
- Testing
- CDX-011, Capecitabine
- Where
- 140 sites in United States, Australia and 7 more
- Volunteers
- 327 people
- Sponsor
- Celldex Therapeutics
Liver Abscess
Empirical Intravenous Beta-Lactam Plus Metronidazole Vs Oral Cefixime Plus Metronidazole for the Treatment of Liver Abscess
Liver abscess (LA) is potentially life threatening medical emergency requiring prompt medical intervention. The backbone of therapy is prompt empirical antimicrobial with or without percutaneous drainage/ aspiration of the…
- Trial name
- NCT06847126
- Testing
- Intravenous beta-lactam antimicrobial for 2 weeks Plus Intravenous Metronidazole (750 mg q 8 hourly) for 2 weeks, Tablet Cefixime (200 mg q 12 hourly) for 2 weeks Plus Tablet Metronidazole (800 mg q 8 hourly) for 2 weeks, Standard medical care
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetes Mellitus, Covid19
Individualized, Technological Interventions for Diabetes Care in the COVID-19 Ward
During the current Covid-19 pandemic, many hospitals worldwide have been overwhelmed and strategies based on new technologies have been considered to improve the outcomes in patients with diabetes and Covid-19 and to prevent…
- Trial name
- Initiator (NCT04871958)
- Testing
- Continuous glucose monitoring (CGM, Dexcom G6)
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Federico II University
Vaginosis, Bacterial
Safety and Tolerability of Metronidazole Gel 1.3%
Multicenter, open-label study to evaluate safety and tolerability of Metronidazole Vaginal Gel in females 12 to <18 years for the treatment of bacterial vaginosis.
- Trial name
- NCT02392026
- Testing
- Metronidazole Gel
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Insud Pharma
Diabetic Retinal Disease
Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes
A considerable hurdle to the development of novel, more effective therapies for diabetic retinal disease is the limited number of primary endpoints available for use in regulatory trials.
- Trial name
- AR (NCT07270133)
- Testing
- Visual Acuity, Reading Speed, Visual Field testing
- Where
- 8 sites in United States
- Volunteers
- 450 people
- Sponsor
- Jaeb Center for Health Research
Wound; Perineal Rupture, Dehiscence
Early Resuturing Versus Expectant Management Following Perineal Wound Dehiscence Among Women Who Had a Vaginal Delivery
Women who deliver their baby vaginally often suffer from a perineal wound. The wound is after being sutured sometimes dehisced after days up to a few weeks and this study will investigate whether it is better to resuture early or…
- Trial name
- NCT03806348
- Testing
- Resuturing
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Stockholm South General Hospital
Papulopustular Rosacea
CD5024 1% [Ivermectin 1%] Cream Versus Metronidazole 0.75% Cream in Papulopustular Rosacea (PPR) Study
Study objectives: To compare efficacy and safety of Ivermectin 1% cream versus metronidazole 0.75% cream in subjects with papulopustular rosacea after 16-week topical treatment.
- Trial name
- ATTRACT (NCT01493947)
- Testing
- Ivermectin 1% cream, Metronidazole 0.75% cream
- Where
- 60 sites in Bulgaria, Czechia and 8 more
- Volunteers
- 962 people
- Sponsor
- Galderma R&D
Spinal Cord Injuries (SCI)
Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord Injury
The goal of this clinical trial is to evaluate the safety and effectiveness of Epidural Electrical Stimulation (EES) combined with rehabilitation training for the reconstruction of walking in patients with chronic spinal cord…
- Trial name
- NCT07306052
- Testing
- Epidural spinal cord stimulation, Rehabilitation Therapy, positron emission tomography-computed tomography (PET-CT)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Brain Tumor, Stroke, Acute
Safety and Feasibility of the Infinity Catheter for Radial Access
The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial…
- Conditions
- Brain Tumor, Stroke, Acute, Brain Aneurysm, Intracranial Arteriovenous Malformations
- Trial name
- NCT04553549
- Testing
- Transradial approach
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
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