Clinical trials: Metronidazole
Bacterial Vaginosis
Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)
A double-blind, phase 3 study to determine the efficacy of SPL7013 Gel when administered on alternate days for 16 weeks, compared to placebo gel in preventing the recurrence of BV in women with a history of recurrent BV.
- Trial name
- NCT02236156
- Testing
- Metronidazole oral tablets 500mg, 1% SPL7013 Gel
- Where
- 30 sites in United States, Bulgaria and 4 more
- Volunteers
- 637 people
- Sponsor
- Starpharma Pty Ltd
Chronic Periodontitis, Generalized
The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients
Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?
- Trial name
- NCT03783845
- Testing
- amoxicillin 500mg and metronidazole 400mg
- Volunteers
- 44 people
- Sponsor
- Taibah University
Periodontal Disease
Periodontal Disease Treatment of a Physically Challenged Population
Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush.
- Trial name
- PDT (NCT01718912)
- Testing
- metronidazole-nystatin oral rinse
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Oravital Inc
Antibacterial Agents, Ambulatory Care
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Many clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus.
- Trial name
- NCT06144242
- Testing
- Feedback on RTD metric
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daniel Livorsi
Prostate Cancer Patients
C-Acetate PET/CT Imaging to Evaluate Treatment Changes in Prostate Cancer
Patients with castrate resistant prostate cancer (CRPCA) with osseous metastatic disease planning to undergo Ra-223 therapy may be eligible for this study.
- Trial name
- NCT02715583
- Testing
- 11C-Acetate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Neurofibromatosis Type 1
Gait in Young Children With NF1
The objective of this study is to develop office-based tools to quantify gait in young children with NF1 that reflect overall gross motor impairment and predict future gross motor difficulties.
- Trial name
- NCT07564622
- Volunteers
- 56 people
- Sponsor
- NYU Langone Health
Study Focus: Simulation and Proficiency Based Training
Proficiency Based Training in Surgery - Employing An Arthroscopic Bankart Repair
This study examines in a prospective, randomized and blinded study design the impact of a proficiency based training methodology on the acquisition of arthroscopic surgical skills employing both a dry shoulder simulator model…
- Trial name
- NCT01921621
- Testing
- Group B - Simulation Training, Group C - Proficiency Based Progression
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Arthroscopy Association of North America
Propionic Acidemia, Methylmalonic Acidemia
Carglumic Acid in Methylmalonic Acidemia and Propionic Acidemia
A Phase IIIb (Three b), Randomized Multicentre Comparative Trial to Evaluate the Long Term Effectiveness \& Safety of the use of Carglumic Acid (Carbaglu®) in Patients with Propionic Acidemia (PA) or Methylmalonic Acidemia (MMA).
- Trial name
- CAMP (NCT02426775)
- Testing
- Carglumic Acid
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 33 people
- Sponsor
- King Abdullah International Medical Research Center
Rosacea, Erythematotelangiectatic
Metronidazole SC Penetrance With Moisturizers
Topical metronidazole is a widely used first line treatment for erythemotelangiectatic and inflammatory rosacea. Commonly, a moisturizer is also used to restore the skin barrier and reduce inflammation.
- Trial name
- NCT06434519
- Testing
- Metronidazole cream, Cetaphil moisturizer, CeraVe moisturizer
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Quality Improvement
The Effect of a Novel Audit and Feedback Bundle on Inpatient Performance
This single-blinded, cluster randomized control trial will assess the effectiveness of an audit and feedback bundle on internal medicine physician performance on selected quality metrics.
- Trial name
- NCT02593253
- Testing
- Audit and Feedback Bundle, Bi-weekly audit and feedback emails
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Acute Cholecystitits
The Role of Antibiotic Treatment in Patients With Acute Mild Cholecystitis - A Prospective Randomized Controlled Trial
The treatment of acute cholecystitis includes limited oral intake, antibiotics and early or delayed surgery. To date there are no randomized trials proving the benefit of antibiotic treatment.
- Trial name
- NCT00557453
- Testing
- Antibiotic treatment, No antibiotics
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hadassah Medical Organization
Cancer, Diabetes
Monitoring Your Exercise-related Metrics Over Time Via Wearable Electronic Devices
To test the use of a continuous activity and heart rate tracker (Fitbit) and continuous glucose monitor (CGM) in monitoring daily exercise-related activities.
- Trial name
- NCT05124405
- Testing
- Fitbit, Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Peri-Implantitis
Surgical Treatment of Peri-implantitis
The aim of this randomized controlled study is to evaluate the outcome of surgical treatment of peri-implantitis with and without the use of a bone substitute graft covered by a collagen membrane.
- Trial name
- STP (NCT03163602)
- Testing
- Control group, Test group
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Relationship, Family, Well-Being, Psychological
REducing pSychological diSTress To Optimize Recovery of Elderly ICU Survivors and Caregivers (RESTORE-ICU)
This research study aims to explore whether a set of simple breathing techniques and guided meditations can improve the psychological well-being and recovery of ICU survivors and their caregivers.
- Trial name
- RESTORE-ICU (NCT06867367)
- Testing
- Isha Kriya and Naddi Shuddhi
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Appendicitis
Acute Appendicitis: Active Observation With and Without Antibiotics
This study evaluates if early provision of antibiotics is a superior treatment compared to "traditional wait and see" with regard to symptom relief for suspected acute uncomplicated appendicitis.
- Trial name
- NCT03985514
- Testing
- Antibiotic treatment (Piperacillin/Tazobactam, 4 gram x 3), followed by 8-10 days of out-hospital oral antibiotic treatment (Ciprofloxacin 500 mgx2,Flagyl 400 mgx3)., Active observation
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Göteborg University
Diabetes Mellitus, Covid19
Individualized, Technological Interventions for Diabetes Care in the COVID-19 Ward
During the current Covid-19 pandemic, many hospitals worldwide have been overwhelmed and strategies based on new technologies have been considered to improve the outcomes in patients with diabetes and Covid-19 and to prevent…
- Trial name
- Initiator (NCT04871958)
- Testing
- Continuous glucose monitoring (CGM, Dexcom G6)
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Federico II University
Cholecystitis
Effect Of Early Versus Delayed Laparoscopic Cholecystectomy In Patients With Grade II Cholecystitis
The timing ofthe cholecystectomy in patients with acute cholecystitis is still controversial. In our study, we aimed toinvestigate the effect of early and delayed cholecystectomy on difficultcholecystectomy, morbidity and…
- Trial name
- NCT05352087
- Testing
- Laparoscopic cholecystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Tepecik Training and Research Hospital
Laryngopharyngeal Reflux, Laryngopharyngitis Chronic
Method of Early Diagnosis of Laryngopharyngeal Reflux
The investigator will issue a Patient Information Consent for the participant in the study. 1.Patients will be asked to complete the Reflux Symptom Index questionnaire. Clinical survey, medical history. 2.
- Conditions
- Laryngopharyngeal Reflux, Laryngopharyngitis Chronic, Gastro Esophageal Reflux, Laryngitis
- Trial name
- LPR (NCT04771221)
- Testing
- pH metry, Filling out the questionnaire, Endoscopic laryngoscopy
- Where
- 2 sites in Kazakhstan
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Gastroparesis
GI-Challenge Study for Gastroparesis Patients and Healthy Controls
Gastroparesis Patients and Healthy Controls ages 20-49 will be asked to participate in an observational study measuring vagal activity following food ingestion in order to establish parameters of autonomic nerve/vagal function in…
- Trial name
- NCT03896126
- Testing
- Observational
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
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