Clinical trials: Morphine, completed
Premature Neonates
Optimizing the Use of Morphine in Pre-Term Neonates
The purpose of this study is to improve the dosing of morphine in critically ill premature neonates.
- Trial name
- NCT00494429
- Testing
- Morphine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- John van den Anker
Acute Pain
IV Acetaminophen as an Analgesic Adjunct
To determine the efficacy of intravenous (IV) acetaminophen as an analgesic adjunct to IV hydromorphone in the treatment of acute severe pain in the elderly Emergency Department (ED) patients.
- Trial name
- NCT02621619
- Testing
- IV acetaminophen + 0.5 mg IV hydromorphone, Normal saline + 0.5 mg IV hydromorphone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Montefiore Medical Center
Dental Pain
Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
The purpose of this study is to assess the activity of buprenorphine hydrochloride (HCl) buccal film in the treatment of dental pain.
- Trial name
- NCT00941304
- Testing
- Oxycodone, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- BioDelivery Sciences International
Neonatal Abstinence Syndrome
Buprenorphine for the Treatment of Neonatal Abstinence Syndrome
Neonatal abstinence syndrome is a disease that affects children who were exposed to opioid drugs prior to birth. Commonly used treatments at present include morphine or tincture of opium.
- Trial name
- NCT00521248
- Testing
- buprenorphine, Oral morphine solution
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Other Chronic Postoperative Pain
High Pain Intervention in Cesarean Sections
In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later.
- Trial name
- NCT01298778
- Testing
- Duramorph 150, Acetaminophen, Duramorph 300
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Wake Forest University Health Sciences
Cesarean Delivery; Neuraxial Opioids
Respiratory Rate After Cesarean Delivery
The study proposal summarizes aspects related to respiratory rate in women who undergo spinal anesthesia for cesarean delivery who receive or do not receive neuraxial opioids
- Trial name
- NCT04250233
- Testing
- Respiratory Monitor
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Postoperative
Local Anesthetic Continuous Preperitoneal Infiltration and Wound Hyperalgesia
In this multicenter, randomised, placebo-controlled, double-blind trial, hyperalgesia area around the scarce following colorectal laparoscopic surgery (piece removal) will be assessed in 3 groups of patients : group 1: continuous…
- Trial name
- CATCH (NCT01077752)
- Testing
- continuous ropivacaine preperitoneal infusion, intravenous lidocaine infusion, parenteral analgesia combining acetaminophen and morphine
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Postoperative
Cortical Modulation of Acute Post-thoracotomy Pain With Transcranial Direct Current Stimulation
The primary objective of this single center, prospective, randomized, double blind clinical trial is to evaluate the effectiveness of anodal transcranial direct current stimulation (tDCS) combined with patient controlled…
- Trial name
- CMAPTPtDCS (NCT03005548)
- Testing
- Transcranial direct current stimulation, Morphine
- Where
- Serbia
- Volunteers
- 62 people
- Sponsor
- Military Medical Academy, Belgrade, Serbia
Opioid Use
Does Altering Narcotic Prescription Methods Affect Opioid Distribution Following Select Upper Extremity Surgeries?
It has been well established that prescription opioid misuse and prescription opioid abuse is on the rise. In the late 1990's and early 2000's, there was a large push to make "pain" the fifth vital sign.
- Trial name
- NCT03570320
- Testing
- Modification of opioid prescription method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- John Yanik
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Post Operative Pain
External Oblique Intercostal Plane Block for Patients Undergoing Upper Abdominal Surgeries
Ithe study will evaluate the analgesic efficacy of external oblique intercostal block for patients undergoing upper abdominal surgeries
- Trial name
- EOINB (NCT06514417)
- Testing
- US-guided external oblique intercostal block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Postoperative Pain
Quadratus Lumborum Block for Total Abdominal Hysterectomy
Procedure specific postoperative pain management (PROSPECT) guidelines for abdominal hysterectomy published in 2006 recommended laparoscopic or vaginal hysterectomy as a preferred surgical technique.
- Trial name
- NCT05765318
- Testing
- QLB
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Clinical Center Niš
Cancer, Surgery
Anesthesia Feasibility Study With the CONCERT-CL® Station
This is a feasibility study of anesthesia in closed loop with the CONCERT-CL® station, on the effect of the hypnotic agent, measured by the bispectral index of the electroencephalogram, to maintain the hypnosis level within the…
- Trial name
- CONCERT (NCT02889718)
- Testing
- CONCERT-CL® station, Surgery
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut Cancerologie de l'Ouest
Analgesia
Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal…
- Trial name
- NCT05042817
- Testing
- 100 mcg morphine, 0.9% NaCl, 50 mg prilocaine + 2.5 mcg sufentanil
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Surgical Wound, Post-Op Complication
CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery
Major abdominal surgery is associated with significant complications which may lead to morbidity and mortality. Pain experienced after surgery affects the recovery from surgery.
- Conditions
- Surgical Wound, Post-Op Complication, Opioid Use
- Trial name
- CLoWI (NCT04503720)
- Testing
- CLoWI, PCA
- Where
- 2 sites in Singapore
- Volunteers
- 52 people
- Sponsor
- JurongHealth
Motivation, Drug Effect
How Stress Alters Opioid Drug Effects
The main objective of the study is to test the hypothesis that opioid drug effects vary as a function of pre-drug affective state.
- Conditions
- Motivation, Drug Effect, Stress Reaction, Misuse, Opioid
- Trial name
- OPIOIDREWARD (NCT06485817)
- Testing
- Oxycodone, Stress State Induction, Control State Induction
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Physical Activity
Cross Sectional Study to Evaluate Effects of Kinesiotaping on Muscle Activity During Climbing Stairs and Sport Activity
This study aims to evaluate the effects of IQ-Tape, Kinesiotaping and no Taping on muscle activity during daily activity and sport activity.
- Trial name
- NCT02802410
- Testing
- IQ-Tape, Kinesiotape, No-Tape
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Postoperative Recovery
Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score
The aim of this study is to evaluate the effects of three different postsesarean analgesia techniques, including instillation of local anesthetic into the peritoneum with infiltration into all layers of the anterior abdominal…
- Trial name
- NCT06341049
- Testing
- Intraperitoneal local anasthetic application + local anesthetic wound infiltration, Intrathecal morphine application, Quadratus lumborum block tip 1 application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Musculoskeletal Injury
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
Musculoskeletal (MSK) injuries, including limb injuries, are the most common cause for Emergency Department (ED) visits for children with pain.
- Trial name
- No OUCH (NCT03767933)
- Testing
- Ibuprofen, Acetaminophen, Hydromorphone
- Where
- 6 sites in Canada
- Volunteers
- 710 people
- Sponsor
- University of Alberta
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